TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

MYOCARDIAL CELL [4 records]

Record 1 2014-11-05

English

Subject field(s)
  • Cytology
  • The Heart
DEF

A general term for cells contributing to heart muscle.

CONT

One important type of cell that can be developed is the cardiomyocyte, the heart muscle cell that contracts to eject the blood out of the heart’s main pumping chamber (the ventricule).

Key term(s)
  • cardio-myocyte

French

Domaine(s)
  • Cytologie
  • Cœur
DEF

Cellule musculaire cardiaque.

CONT

Le muscle cardiaque est constitué de cellules, les cardiomyocytes, liés les uns aux autres par des disques intercalaires. Les embranchements des cardiomyocytes forment un réseau complexe tridimensionnel. Tous les cardiomyocytes sont capables de dépolarisations rythmiques spontanées.

Spanish

Save record 1

Record 2 2010-11-16

English

Subject field(s)
  • Chemical Elements and Compounds
  • Medication
Universal entry(ies)
63675-72-9
CAS number
C20H24N2O6
formula, see observation
CONT

Nisoldipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal' s variant angina. Nisoldipine is similar to other peripheral vasodilators. Nisoldipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum.

OBS

Active ingredient commonly sold under the name Sular.

OBS

Chemical formula: C20H24N2O6

French

Domaine(s)
  • Éléments et composés chimiques
  • Médicaments
Entrée(s) universelle(s)
63675-72-9
CAS number
C20H24N2O6
formula, see observation
CONT

Des canaux calciques potentiel-dépendants ont récemment été découverts dans des cellules de Kupffer isolées [...], et la nisoldipine, un inhibiteur calcique, diminue la phagocytose des particules dans le foie de rat conservé [...]

OBS

Principe actif couramment commercialisé sous le nom de Sular.

OBS

Formule chimique : C20H24N2O6

Spanish

Save record 2

Record 3 2002-03-08

English

Subject field(s)
  • Biochemistry
CONT

Selectines facilitate the initial adhesion of leukocytes on the surface of vascular endothelium. This initial adhesion is considered to be the first step in the development of the atherosclerotic plaque. Adhered leukocytes migrate into the subendothelial space and form the so-called "foam" cells at a later stage. Three different selectine molecule have been identified : L-selectine is expressed on the leucocyte membrane, E-selectine is expressed on the "activated" endothelial cell membrane and P-selectine is expressed on both platelet and "activated" endothelial cell surface. P-selectine seems to play a role in the development of acute coronary syndromes. Increased serum levels of P-selectine have been found in both acute myocardial infarction and unstable angina.

French

Domaine(s)
  • Biochimie
CONT

Par ailleurs, une cascade inflammatoire maintenant classique est activée lors de la CEC : neutrophiles, système du complément, IL1, IL6 en particulier. La thrombine est une enzyme multifonctionnelle qui possède une action inflammatoire avec expression de P-sélectine, de PAF [platelet activating factor], et de facteur de chemotactisme. Directement sur les cellules c'est un facteur mitogène sur les plaquettes par le TGF [transforming growth factor] beta et le PDGF [platelet derived growth factor] ainsi que sur l'endothélium.

Spanish

Save record 3

Record 4 2001-03-01

English

Subject field(s)
  • The Heart
CONT

Acute ischemia results in a spectrum of deleterious effects, ranging from transient depression of contractile function(myocardial "stunning" and "hibernation") to severe abnormalities, such as reperfusion-induced lethal arrhythmias and accelerated myocardial cell death(both necrosis and apoptosis).

Key term(s)
  • stunning

French

Domaine(s)
  • Cœur
CONT

Il existe quatre formes reconnues de lésions de reperfusion («reperfusion injury» des anglo-saxons) [...] : les arythmies de reperfusion, les dommages vasculaires et le phénomène de «no-reflow», la sidération myocardique («myocardial stunning»), et la nécrose de reperfusion.

Key term(s)
  • sidération

Spanish

Save record 4

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