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POLYGENIC OBESITY [2 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2024-09-23

English

Subject field(s)
  • Hygiene and Health
  • Genetics
CONT

... rare forms of monogenic obesity distinguish themselves from polygenic obesity, which is the most common clinical situation... In polygenic obesity, each susceptibility gene, taken individually, would only have a slight effect on weight. Furthermore, the cumulative contribution of these genes would become significant only in an obesogenic environment(such as overfeeding, sedentary living, stress, etc.).

French

Domaine(s)
  • Hygiène et santé
  • Génétique
CONT

Comme pour toutes les maladies multifactorielles, la contribution de l'hérédité à l'obésité peut être schématisée : - par mutations rares des gènes à fort impact sur l'obésité [...] - soit par l'interaction de plusieurs variants géniques avec un environnement permissif (obésité polygénique). Chaque gène de susceptibilité pris individuellement a de faibles effets sur le poids, et la contribution cumulative de ces gènes ne devient significative qu'en interaction avec des facteurs environnementaux prédisposant à leur expression phénotypique.

Spanish

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Record 2 2024-08-19

English

Subject field(s)
  • Hygiene and Health
  • Genetics
CONT

Genetic obesity is categorized into several types based on the way genes are involved... Monogenic obesity : Excessive weight caused by a mutation in a single gene.... Polygenic obesity : Variations in multiple genes contribute to the susceptibility to obesity in small ways.... Syndromic obesity : Genetic changes in specific diseases, like Prader-Willi syndrome, can directly lead to obesity.

French

Domaine(s)
  • Hygiène et santé
  • Génétique

Spanish

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