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POLYNUCLEOTIDE [24 records]
Record 1 - internal organization data 2013-11-15
Record 1, English
Record 1, Subject field(s)
- Genetics
Record 1, Main entry term, English
- complementary chain
1, record 1, English, complementary%20chain
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Because of specific base pairing, if the sequence of one chain(for example, TCGCAT) is known, that of its partner(AGCGTA) is also known. The opposing sequences are referred to as complementary, and the corresponding polynucleotide partners as complementary chains. Despite the relative weakness of the hydrogen bonds holding the base pairs together, each DNA molecule contains so many base pairs that the complementary chains never spontaneously separate under physiological conditions. 1, record 1, English, - complementary%20chain
Record 1, French
Record 1, Domaine(s)
- Génétique
Record 1, Main entry term, French
- chaîne complémentaire
1, record 1, French, cha%C3%AEne%20compl%C3%A9mentaire
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
La molécule ADN est composée de deux chaînes polynucléotidiques complémentaires liées par des liaisons hydrogènes, ce qui implique l'existence de ponts hydrogènes spécifiques. Lors de la réplication chaque chaîne a un rôle matriciel, ce qui implique un mode de réplication semi-conservatif. L'hypothèse de Watson et Crick suggère que la polarité des chaînes complémentaires de l'ADN est inversée et elle suppose en sus que séparation et déspiralisation des chaînes débutent d'un côté de la molécule et se poursuivent progressivement d'un bout à l'autre de la chaîne à la manière de l'ouverture d'une fermeture éclair, la synthèse au sens physique du terme se faisant donc dans une seule direction, ce qui implique que cette synthèse se fait dans des directions chimiques opposées. 2, record 1, French, - cha%C3%AEne%20compl%C3%A9mentaire
Record 1, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 2013-11-15
Record 2, English
Record 2, Subject field(s)
- Genetics
Record 2, Main entry term, English
- 5’ end
1, record 2, English, 5%26rsquo%3B%20end
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
- 5’ terminus 2, record 2, English, 5%26rsquo%3B%20terminus
correct
- 5’ tip 3, record 2, English, 5%26rsquo%3B%20tip
correct
Record 2, Textual support, English
Record number: 2, Textual support number: 1 DEF
The beginning of polynucleotide chain which has a free 5’ group. All RNA chains, as well as DNA chains, grow in the 5’-to-3’ direction. The 5’ position of one pentose ring is connected to the 3’ position of the next pentose ring via a phosphate group. 2, record 2, English, - 5%26rsquo%3B%20end
Record number: 2, Textual support number: 1 OBS
It is conventional to write nucleic acid sequences from the 5’ terminus toward the 3’ terminus. 4, record 2, English, - 5%26rsquo%3B%20end
Record 2, French
Record 2, Domaine(s)
- Génétique
Record 2, Main entry term, French
- extrémité 5'
1, record 2, French, extr%C3%A9mit%C3%A9%205%27
correct, feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 DEF
Commencement d'une chaîne de polynucléotides (dans l'ARN ou l'ADN), la polymérisation se faisant dans le sens 5'-Phosphate [...] 3'-OH (5' et 3' étant les numéros des carbones du sucre impliqués dans la liaison phosphodiester). 2, record 2, French, - extr%C3%A9mit%C3%A9%205%27
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 2013-11-15
Record 3, English
Record 3, Subject field(s)
- Genetics
Record 3, Main entry term, English
- 3’ end
1, record 3, English, 3%26rsquo%3B%20end
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
- 3’ terminus 2, record 3, English, 3%26rsquo%3B%20terminus
correct
Record 3, Textual support, English
Record number: 3, Textual support number: 1 DEF
The end of a polynucleotide chain terminating with A 3’ carbon atom. The 5’ position of one pentose ring is connected to the 3’ position of the next pentose ring via a phosphate group. All RNA chains, as well as DNA chains, grow in the 5’-to-3’ direction. 2, record 3, English, - 3%26rsquo%3B%20end
Record 3, French
Record 3, Domaine(s)
- Génétique
Record 3, Main entry term, French
- extrémité 3'
1, record 3, French, extr%C3%A9mit%C3%A9%203%27
correct, feminine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 DEF
Fin d'une chaîne de polynucléotides (dans l'ARN ou l'ADN), la polymérisation se faisant dans le sens 5'-Phosphate [...] 3'-OH (5' et 3' étant les numéros des carbones du sucre impliqués dans la liaison phosphodiester). 2, record 3, French, - extr%C3%A9mit%C3%A9%203%27
Record 3, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 2013-11-15
Record 4, English
Record 4, Subject field(s)
- Genetics
Record 4, Main entry term, English
- minus strand
1, record 4, English, minus%20strand
correct
Record 4, Abbreviations, English
Record 4, Synonyms, English
- strand 2, record 4, English, strand
correct
Record 4, Textual support, English
Record number: 4, Textual support number: 1 DEF
Complementary strand of polynucleotide formed by transcription from a specific polynucleotide(’plus’) strand. 3, record 4, English, - minus%20strand
Record 4, French
Record 4, Domaine(s)
- Génétique
Record 4, Main entry term, French
- chaîne négative
1, record 4, French, cha%C3%AEne%20n%C3%A9gative
correct, feminine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
- chaîne 2, record 4, French, cha%C3%AEne
correct, feminine noun
- brin négatif 2, record 4, French, brin%20n%C3%A9gatif
correct, masculine noun
- brin 2, record 4, French, brin
correct, masculine noun
Record 4, Textual support, French
Record number: 4, Textual support number: 1 DEF
Chaîne nucléotidique complémentaire synthétisée à partir d'une chaîne que l'on désigne par (+). 2, record 4, French, - cha%C3%AEne%20n%C3%A9gative
Record 4, Spanish
Record 4, Textual support, Spanish
Record 5 - internal organization data 2013-11-15
Record 5, English
Record 5, Subject field(s)
- Genetics
Record 5, Main entry term, English
- complementary base sequence
1, record 5, English, complementary%20base%20sequence
correct
Record 5, Abbreviations, English
Record 5, Synonyms, English
Record 5, Textual support, English
Record number: 5, Textual support number: 1 DEF
Sequence of nucleotides in a polynucleotide chain, as determined by the order of purine and pyrimidine bases of the nucleotides in the parent chain. Adenine pairs with thymine and guanine pairs with cytosine, and these pairs are complementary. 1, record 5, English, - complementary%20base%20sequence
Record 5, French
Record 5, Domaine(s)
- Génétique
Record 5, Main entry term, French
- séquence nucléotidique complémentaire
1, record 5, French, s%C3%A9quence%20nucl%C3%A9otidique%20compl%C3%A9mentaire
correct, feminine noun
Record 5, Abbreviations, French
Record 5, Synonyms, French
Record 5, Textual support, French
Record number: 5, Textual support number: 1 DEF
Séquences de polynucléotides conformes aux règles de complémentarité des bases. Où les bases A se lient sélectivement avec les bases T ou U, les bases C avec les bases G, assurant la cohésion de deux chaînes de DNA ou RNA. 2, record 5, French, - s%C3%A9quence%20nucl%C3%A9otidique%20compl%C3%A9mentaire
Record 5, Spanish
Record 5, Textual support, Spanish
Record 6 - internal organization data 2012-09-12
Record 6, English
Record 6, Subject field(s)
- Genetics
- Biochemistry
Record 6, Main entry term, English
- DNA ligase
1, record 6, English, DNA%20ligase
correct
Record 6, Abbreviations, English
Record 6, Synonyms, English
- ligase 2, record 6, English, ligase
correct
- deoxyribonucleic acid ligase 3, record 6, English, deoxyribonucleic%20acid%20ligase
correct
- DNA joinase 3, record 6, English, DNA%20joinase
correct
- DNA sealase 3, record 6, English, DNA%20sealase
correct
- sealase 3, record 6, English, sealase
correct
- joining enzyme 3, record 6, English, joining%20enzyme
correct
- polynucleotide synthetase 4, record 6, English, polynucleotide%20synthetase
correct
- synthetase 5, record 6, English, synthetase
correct
- polydeoxyribonculeotide synthetase 6, record 6, English, polydeoxyribonculeotide%20synthetase
correct
- polynucleotide ligase 3, record 6, English, polynucleotide%20ligase
correct
Record 6, Textual support, English
Record number: 6, Textual support number: 1 DEF
An enzyme that creates a phosphodiester bond between the 3" end of one DNA segment and the 5" end of another, while they are base-paired to a template strand. 7, record 6, English, - DNA%20ligase
Record 6, French
Record 6, Domaine(s)
- Génétique
- Biochimie
Record 6, Main entry term, French
- ligase
1, record 6, French, ligase
correct, feminine noun, standardized
Record 6, Abbreviations, French
Record 6, Synonyms, French
- ADN ligase 2, record 6, French, ADN%20ligase
correct, feminine noun
- polynucléotide ligase 3, record 6, French, polynucl%C3%A9otide%20ligase
correct, feminine noun
- ADN-ligase 3, record 6, French, ADN%2Dligase
correct, feminine noun
- synthétase 4, record 6, French, synth%C3%A9tase
correct, feminine noun
Record 6, Textual support, French
Record number: 6, Textual support number: 1 DEF
Enzyme catalysant la liaison covalente entre les bases azotées de deux polynucléotides adjacents. [Définition normalisée par l'AFNOR et reproduite avec son autorisation.] 5, record 6, French, - ligase
Record number: 6, Textual support number: 1 OBS
ligase : terme normalisé par l'AFNOR. 6, record 6, French, - ligase
Record 6, Spanish
Record 6, Campo(s) temático(s)
- Genética
- Bioquímica
Record 6, Main entry term, Spanish
- ligasa
1, record 6, Spanish, ligasa
correct, feminine noun
Record 6, Abbreviations, Spanish
Record 6, Synonyms, Spanish
- ADN ligasa 2, record 6, Spanish, ADN%20ligasa
correct, feminine noun
- sintetasa 3, record 6, Spanish, sintetasa
correct, feminine noun
Record 6, Textual support, Spanish
Record number: 6, Textual support number: 1 DEF
Enzima que cataliza la reacción que une dos moléculas de ADN [ácido desoxirribonucleico] a través de la formación de un enlace fosfodiéster entre el extremo 3'-hidroxilo de una y el 5'-fosfato de la otra; su cometido natural es por lo tanto la reparación y replicación del ADN. 2, record 6, Spanish, - ligasa
Record number: 6, Textual support number: 1 OBS
En la tecnología del ADN [ácido desoxirribonucleico] recombinante constituye una herramienta imprescindible, ya que permite la incorporación del ADN exógeno en los vectores de clonación. 2, record 6, Spanish, - ligasa
Record 7 - internal organization data 2012-09-10
Record 7, English
Record 7, Subject field(s)
- Genetics
Record 7, Main entry term, English
- restriction fragment
1, record 7, English, restriction%20fragment
correct
Record 7, Abbreviations, English
Record 7, Synonyms, English
Record 7, Textual support, English
Record number: 7, Textual support number: 1 DEF
Any of the individual polynucleotide sequences produced by digestion of deoxyribonucleic acid with a restriction endonuclease. 2, record 7, English, - restriction%20fragment
Record 7, French
Record 7, Domaine(s)
- Génétique
Record 7, Main entry term, French
- fragment de restriction
1, record 7, French, fragment%20de%20restriction
correct, masculine noun
Record 7, Abbreviations, French
Record 7, Synonyms, French
Record 7, Textual support, French
Record number: 7, Textual support number: 1 CONT
Nos sujets sont la caractérisation de polymorphismes de fragment de restriction de l'ADN (RFLP) associés au phénotype de troubles affectifs bipolaires, l'identification du gène responsable du glaucome juvénile à angle ouvert, l'identification de l'enzyme responsable dans la dystrophie myotonique de Steinert, tout comme l'hybridation «in situ» chromosomique pour des fins diagnostiques et de recherche [...] 2, record 7, French, - fragment%20de%20restriction
Record 7, Spanish
Record 7, Campo(s) temático(s)
- Genética
Record 7, Main entry term, Spanish
- fragmento de restricción
1, record 7, Spanish, fragmento%20de%20restricci%C3%B3n
correct, masculine noun
Record 7, Abbreviations, Spanish
Record 7, Synonyms, Spanish
Record 7, Textual support, Spanish
Record number: 7, Textual support number: 1 DEF
Molécula acortada de ADN generada por la rotura de una molécula mayor por la acción de una o más endonucleasas de restricción. 1, record 7, Spanish, - fragmento%20de%20restricci%C3%B3n
Record 8 - internal organization data 2012-08-06
Record 8, English
Record 8, Subject field(s)
- Genetics
Record 8, Main entry term, English
- deoxyribonuclease
1, record 8, English, deoxyribonuclease
correct
Record 8, Abbreviations, English
Record 8, Synonyms, English
- DNAse 2, record 8, English, DNAse
correct
- DNase 2, record 8, English, DNase
correct
Record 8, Textual support, English
Record number: 8, Textual support number: 1 DEF
One of a group of enzymes, endodeoxyribonucleases, found in bacterial, yeast, and mammalian tissues, that catalyze the degradation of deoxyribonucleic acid (DNA). 3, record 8, English, - deoxyribonuclease
Record number: 8, Textual support number: 1 OBS
The enzymes are important in the repair of defective DNA, acting by catalyzing the hydrolytic cleavage of a continuous polynucleotide chain near a site of distortion. 3, record 8, English, - deoxyribonuclease
Record 8, French
Record 8, Domaine(s)
- Génétique
Record 8, Main entry term, French
- désoxyribonucléase
1, record 8, French, d%C3%A9soxyribonucl%C3%A9ase
correct, feminine noun
Record 8, Abbreviations, French
Record 8, Synonyms, French
- DNase 2, record 8, French, DNase
correct
- ADN-ase 2, record 8, French, ADN%2Dase
correct
Record 8, Textual support, French
Record number: 8, Textual support number: 1 DEF
Enzyme qui catalyse l'hydrolyse des acides désoxyribonucléiques en nucléotides ou polynucléotides. 3, record 8, French, - d%C3%A9soxyribonucl%C3%A9ase
Record 8, Spanish
Record 8, Campo(s) temático(s)
- Genética
Record 8, Main entry term, Spanish
- desoxirribonucleasa
1, record 8, Spanish, desoxirribonucleasa
correct, feminine noun
Record 8, Abbreviations, Spanish
Record 8, Synonyms, Spanish
- ADNasa 2, record 8, Spanish, ADNasa
correct, feminine noun
- dornasa 3, record 8, Spanish, dornasa
correct, feminine noun
Record 8, Textual support, Spanish
Record number: 8, Textual support number: 1 DEF
Cualquier enzima que cataliza la rotura de los enlaces fosfodiéster del ADN. 2, record 8, Spanish, - desoxirribonucleasa
Record number: 8, Textual support number: 1 CONT
La ADNasa I es una endonucleasa digestiva secretada por el páncreas, que degrada el ADN en fragmentos más cortos. Existen otras muchas endonucleasas y exonucleasas que están implicadas en la reparación y la replicación del ADN. 2, record 8, Spanish, - desoxirribonucleasa
Record number: 8, Textual support number: 1 OBS
Dornasa es un término abreviado para desoxirribonucleasa. 4, record 8, Spanish, - desoxirribonucleasa
Record 9 - internal organization data 2012-05-01
Record 9, English
Record 9, Subject field(s)
- Genetics
- Molecular Biology
Record 9, Main entry term, English
- polynucleotide kinase
1, record 9, English, polynucleotide%20kinase
correct
Record 9, Abbreviations, English
Record 9, Synonyms, English
Record 9, Textual support, English
Record number: 9, Textual support number: 1 DEF
Enzyme that catalyzes the transfer of the [gamma] -phosphate of ATP to a 5’-OH terminus in DNA or RNA. 2, record 9, English, - polynucleotide%20kinase
Record number: 9, Textual support number: 1 OBS
It is used for labeling 5’ termini in DNA for sequencing by the Maxam-Gilbert technique. 2, record 9, English, - polynucleotide%20kinase
Record 9, French
Record 9, Domaine(s)
- Génétique
- Biologie moléculaire
Record 9, Main entry term, French
- polynucléotide kinase
1, record 9, French, polynucl%C3%A9otide%20kinase
correct, masculine noun, standardized
Record 9, Abbreviations, French
Record 9, Synonyms, French
Record 9, Textual support, French
Record number: 9, Textual support number: 1 DEF
Enzyme phosphorylant la partie terminale d'un polynucléotide. [Définition normalisée par l'AFNOR et reproduite avec son autorisation.] 2, record 9, French, - polynucl%C3%A9otide%20kinase
Record number: 9, Textual support number: 1 OBS
polynucléotide kinase : terme normalisé par l'AFNOR et publié au Journal officiel de la République française le 22 septembre 2000. 3, record 9, French, - polynucl%C3%A9otide%20kinase
Record 9, Spanish
Record 9, Textual support, Spanish
Record 10 - internal organization data 2012-03-16
Record 10, English
Record 10, Subject field(s)
- Genetics
Record 10, Main entry term, English
- codon
1, record 10, English, codon
correct
Record 10, Abbreviations, English
Record 10, Synonyms, English
- coding unit 2, record 10, English, coding%20unit
correct
- code word 3, record 10, English, code%20word
correct
- coding triplet 3, record 10, English, coding%20triplet
correct
Record 10, Textual support, English
Record number: 10, Textual support number: 1 DEF
A series of three adjacent nucleotides in one polynucleotide chain of a DNA or RNA molecule, which directs the insertion of a specific amino acid in the growing polypeptide chain during protein synthesis. 4, record 10, English, - codon
Record number: 10, Textual support number: 1 CONT
The genetic code has four elements (bases or letters), rather than the two of the binary system. The bases are grouped together in threes, known as codons, rather than the eight-bit bytes of computing. 5, record 10, English, - codon
Record 10, French
Record 10, Domaine(s)
- Génétique
Record 10, Main entry term, French
- codon
1, record 10, French, codon
correct, masculine noun, standardized
Record 10, Abbreviations, French
Record 10, Synonyms, French
- unité de codage 2, record 10, French, unit%C3%A9%20de%20codage
correct, feminine noun
Record 10, Textual support, French
Record number: 10, Textual support number: 1 DEF
Triplet de nucléotides de l'ARNm. [Définition normalisée par l'AFNOR et reproduite avec son autorisation.] 3, record 10, French, - codon
Record number: 10, Textual support number: 1 OBS
L'appariement codon-anticodon permet le positionnement de l'acide aminé dans une chaîne polypeptique en voie de synthèse. [Observation reproduite avec l'autorisation de l'AFNOR.] 3, record 10, French, - codon
Record number: 10, Textual support number: 2 OBS
codon : terme normalisé par l'AFNOR. 4, record 10, French, - codon
Record 10, Spanish
Record 10, Campo(s) temático(s)
- Genética
Record 10, Main entry term, Spanish
- codón
1, record 10, Spanish, cod%C3%B3n
correct, masculine noun
Record 10, Abbreviations, Spanish
Record 10, Synonyms, Spanish
Record 10, Textual support, Spanish
Record number: 10, Textual support number: 1 DEF
Secuencia de tres nucleótidos en una cadena ADN o ARN que constituye información codificada para un aminoácido específico. 2, record 10, Spanish, - cod%C3%B3n
Record 11 - internal organization data 2011-10-17
Record 11, English
Record 11, Subject field(s)
- Biochemistry
- Genetics
Record 11, Main entry term, English
- base sequence
1, record 11, English, base%20sequence
correct
Record 11, Abbreviations, English
Record 11, Synonyms, English
- nucleotide sequence 2, record 11, English, nucleotide%20sequence
correct
Record 11, Textual support, English
Record number: 11, Textual support number: 1 DEF
The specific order and identities of component nucleotides in a polynucleotide denoted by the purine and pyrimidine bases they contain and expressed by the single letter abbreviations used for the nucleotides. 3, record 11, English, - base%20sequence
Record number: 11, Textual support number: 1 CONT
Many base sequences for small RNA molecules are known. Base sequence for DNA species have been determined by various techniques. 3, record 11, English, - base%20sequence
Record 11, French
Record 11, Domaine(s)
- Biochimie
- Génétique
Record 11, Main entry term, French
- séquence des bases
1, record 11, French, s%C3%A9quence%20des%20bases
correct, feminine noun
Record 11, Abbreviations, French
Record 11, Synonyms, French
- séquence des nucléotides 2, record 11, French, s%C3%A9quence%20des%20nucl%C3%A9otides
correct, feminine noun
- séquence nucléotidique 3, record 11, French, s%C3%A9quence%20nucl%C3%A9otidique
correct, feminine noun
Record 11, Textual support, French
Record number: 11, Textual support number: 1 DEF
Séquence des différents nucléotides au sein d'un acide nucléique. 3, record 11, French, - s%C3%A9quence%20des%20bases
Record 11, Spanish
Record 11, Campo(s) temático(s)
- Bioquímica
- Genética
Record 11, Main entry term, Spanish
- secuencia de nucleótidos
1, record 11, Spanish, secuencia%20de%20nucle%C3%B3tidos
correct, feminine noun
Record 11, Abbreviations, Spanish
Record 11, Synonyms, Spanish
Record 11, Textual support, Spanish
Record 12 - internal organization data 2011-06-06
Record 12, English
Record 12, Subject field(s)
- Genetics
Record 12, Main entry term, English
- base pairing
1, record 12, English, base%20pairing
correct
Record 12, Abbreviations, English
Record 12, Synonyms, English
Record 12, Textual support, English
Record number: 12, Textual support number: 1 DEF
The pairing of nitrogenous bases in the polynucleotide chains by hydrogen bonds in a specific manner 1, record 12, English, - base%20pairing
Record 12, French
Record 12, Domaine(s)
- Génétique
Record 12, Main entry term, French
- appariement des bases
1, record 12, French, appariement%20des%20bases
correct, masculine noun
Record 12, Abbreviations, French
Record 12, Synonyms, French
Record 12, Textual support, French
Record number: 12, Textual support number: 1 DEF
Association par liaisons hydrogènes de deux bases dites complémentaires d'un acide nucléique, soit une base purique et une base pyrimidique. 2, record 12, French, - appariement%20des%20bases
Record 12, Spanish
Record 12, Textual support, Spanish
Record 13 - internal organization data 2010-04-29
Record 13, English
Record 13, Subject field(s)
- Genetics
- Molecular Biology
- Biochemistry
Record 13, Main entry term, English
- double-stranded DNA
1, record 13, English, double%2Dstranded%20DNA
correct
Record 13, Abbreviations, English
- dsDNA 2, record 13, English, dsDNA
correct
Record 13, Synonyms, English
- double-strand DNA 3, record 13, English, double%2Dstrand%20DNA
correct
- duplex DNA 2, record 13, English, duplex%20DNA
correct
Record 13, Textual support, English
Record number: 13, Textual support number: 1 DEF
A DNA in which two parallel, complementary polynucleotide chains are maintained in a double-helical conformation by the base pairing of nucleotides on opposite chains. 1, record 13, English, - double%2Dstranded%20DNA
Record 13, Key term(s)
- double stranded DNA, double strand DNA
Record 13, French
Record 13, Domaine(s)
- Génétique
- Biologie moléculaire
- Biochimie
Record 13, Main entry term, French
- ADN double brin
1, record 13, French, ADN%20double%20brin
correct, masculine noun
Record 13, Abbreviations, French
- ADNdb 2, record 13, French, ADNdb
correct, masculine noun
Record 13, Synonyms, French
- ADN à double brin 3, record 13, French, ADN%20%C3%A0%20double%20brin
correct, masculine noun
- ADN bicaténaire 4, record 13, French, ADN%20bicat%C3%A9naire
correct, masculine noun
- DNA bicaténaire 4, record 13, French, DNA%20bicat%C3%A9naire
avoid, masculine noun
Record 13, Textual support, French
Record number: 13, Textual support number: 1 DEF
Structure normale de l'ADN en hélice, formée par l'appariement de deux brins complémentaires. 2, record 13, French, - ADN%20double%20brin
Record number: 13, Textual support number: 1 CONT
La synthèse d'un ADN double brin aboutit à la formation de deux molécules hybrides constituées d'une chaîne parentale et d'une chaîne complémentaire; ces deux molécules hybrides sont identiques l'une à l'autre et à la molécule parentale. Lors du processus de réplication, la double chaîne parentale se sépare en deux brins et chaque brin sert alors de modèle pour la synthèse du brin complémentaire. L'appariement strict de A à T et de G à C garantit une reproduction fidèle. 1, record 13, French, - ADN%20double%20brin
Record number: 13, Textual support number: 1 OBS
S'oppose à «ADN simple brin». 5, record 13, French, - ADN%20double%20brin
Record 13, Spanish
Record 13, Campo(s) temático(s)
- Genética
- Biología molecular
- Bioquímica
Record 13, Main entry term, Spanish
- ADN bicatenario
1, record 13, Spanish, ADN%20bicatenario
correct, masculine noun
Record 13, Abbreviations, Spanish
Record 13, Synonyms, Spanish
- ADN de cadena doble 1, record 13, Spanish, ADN%20de%20cadena%20doble
correct, masculine noun
Record 13, Textual support, Spanish
Record 14 - internal organization data 2010-03-26
Record 14, English
Record 14, Subject field(s)
- Biochemistry
- Molecular Biology
Record 14, Main entry term, English
- polynucleotide
1, record 14, English, polynucleotide
correct
Record 14, Abbreviations, English
Record 14, Synonyms, English
Record 14, Textual support, English
Record number: 14, Textual support number: 1 DEF
A linear sequence of nucleotides, in which the 5’ linked phosphate on one sugar group is covalently linked to the 3’ position on the adjacent sugars. 2, record 14, English, - polynucleotide
Record number: 14, Textual support number: 1 OBS
In the polynucleotide DNA the sugar is deoxyribose and in RNA, ribose. They may be double stranded or single stranded with varying amounts of internal folding. 2, record 14, English, - polynucleotide
Record 14, French
Record 14, Domaine(s)
- Biochimie
- Biologie moléculaire
Record 14, Main entry term, French
- polynucléotide
1, record 14, French, polynucl%C3%A9otide
correct, masculine noun
Record 14, Abbreviations, French
Record 14, Synonyms, French
Record 14, Textual support, French
Record number: 14, Textual support number: 1 DEF
Substance constituée par l'union d'un grand nombre de nucléotides et représentée par les acides ribonucléiques et désoxyribonucléiques. 2, record 14, French, - polynucl%C3%A9otide
Record 14, Spanish
Record 14, Campo(s) temático(s)
- Bioquímica
- Biología molecular
Record 14, Main entry term, Spanish
- polinucleótido
1, record 14, Spanish, polinucle%C3%B3tido
correct, masculine noun
Record 14, Abbreviations, Spanish
Record 14, Synonyms, Spanish
Record 14, Textual support, Spanish
Record 15 - internal organization data 2009-08-18
Record 15, English
Record 15, Subject field(s)
- Biochemistry
Record 15, Main entry term, English
- deoxyribonuclease
1, record 15, English, deoxyribonuclease
correct
Record 15, Abbreviations, English
- DNAse 1, record 15, English, DNAse
correct
- DNase 1, record 15, English, DNase
correct
Record 15, Synonyms, English
- deoxyribonuclease (Pancreatic) 2, record 15, English, deoxyribonuclease%20%28Pancreatic%29
correct
- desoxyribonuclease (pancreatic) 2, record 15, English, desoxyribonuclease%20%28pancreatic%29
correct
- panecreatic desoxyribonuclease 2, record 15, English, panecreatic%20desoxyribonuclease
correct
- pancreatic dornase 2, record 15, English, pancreatic%20dornase
correct
- Deanase 3, record 15, English, Deanase
correct, trademark
- Dinase 3, record 15, English, Dinase
correct, trademark
- Dornavac 2, record 15, English, Dornavac
correct, trademark
- dornase 4, record 15, English, dornase
avoid, see observation
Record 15, Textual support, English
Record number: 15, Textual support number: 1 DEF
One of a group of enzymes, endodeoxyribonucleases(EC 3. 1. 21 and 3. 1. 22), found in bacterial, yeast, and mammalian tissues, that catalyze the degradation of deoxyribonucleic acid(DNA). The enzymes are important in the repair of defective DNA, acting by catalyzing the hydrolytic cleavage of a continuous polynucleotide chain near a site of distortion. 1, record 15, English, - deoxyribonuclease
Record number: 15, Textual support number: 1 OBS
Dornase : Synonym not recommended. 1, record 15, English, - deoxyribonuclease
Record 15, French
Record 15, Domaine(s)
- Biochimie
Record 15, Main entry term, French
- désoxyribonucléase
1, record 15, French, d%C3%A9soxyribonucl%C3%A9ase
correct, feminine noun
Record 15, Abbreviations, French
- ADN-ase 1, record 15, French, ADN%2Dase
correct
Record 15, Synonyms, French
- Deanase 2, record 15, French, Deanase
correct, trademark
- Dinase 2, record 15, French, Dinase
correct, trademark
- Dornavac 2, record 15, French, Dornavac
correct, trademark
- dormase 3, record 15, French, dormase
feminine noun
Record 15, Textual support, French
Record number: 15, Textual support number: 1 DEF
Enzyme qui catalyse l'hydrolyse des acides désoxyribonucléiques en nucléotides ou polynucléotides. 1, record 15, French, - d%C3%A9soxyribonucl%C3%A9ase
Record number: 15, Textual support number: 1 CONT
La désoxyribonucléase I (ADN-ase I, 3.1.4.5) est une enzyme pancréatique qui hydrolyse l'ADN en oligodésoxyribonucléotides : elle rompt les liaisons esters entre l'acide phosphorique et le carbone 3' du ribose du nucléotide précédent; elle est considérée comme l'un des stimulants de la croissance et semble prendre part au mécanisme de la mitose. 1, record 15, French, - d%C3%A9soxyribonucl%C3%A9ase
Record 15, Spanish
Record 15, Campo(s) temático(s)
- Bioquímica
Record 15, Main entry term, Spanish
- desoxirribonucleasa pancreática
1, record 15, Spanish, desoxirribonucleasa%20pancre%C3%A1tica
correct, feminine noun
Record 15, Abbreviations, Spanish
Record 15, Synonyms, Spanish
- dornasa pancreática 2, record 15, Spanish, dornasa%20pancre%C3%A1tica
correct, feminine noun
- dornasa 3, record 15, Spanish, dornasa
correct, feminine noun
Record 15, Textual support, Spanish
Record number: 15, Textual support number: 1 OBS
Dornasa es un término abreviado para desoxirribonucleasa. 4, record 15, Spanish, - desoxirribonucleasa%20pancre%C3%A1tica
Record 16 - internal organization data 2004-12-03
Record 16, English
Record 16, Subject field(s)
- Genetics
- Biochemistry
Record 16, Main entry term, English
- polymerase
1, record 16, English, polymerase
correct
Record 16, Abbreviations, English
Record 16, Synonyms, English
Record 16, Textual support, English
Record number: 16, Textual support number: 1 DEF
Nucleotidyltransferases which catalyse the template-dependent synthesis of polynucleotide chains from ribonucleoside or deoxyribonucleoside 5’-triphosphates. 2, record 16, English, - polymerase
Record 16, French
Record 16, Domaine(s)
- Génétique
- Biochimie
Record 16, Main entry term, French
- polymérase
1, record 16, French, polym%C3%A9rase
correct, feminine noun
Record 16, Abbreviations, French
Record 16, Synonyms, French
Record 16, Textual support, French
Record number: 16, Textual support number: 1 DEF
Enzyme catalysant la liaison des nucléotides entre eux pour former des acides nucléiques à partir de matrices d'ADN ou d'ARN lors des processus de transcription et de réplication. 2, record 16, French, - polym%C3%A9rase
Record 16, Spanish
Record 16, Campo(s) temático(s)
- Genética
- Bioquímica
Record 16, Main entry term, Spanish
- polimerasa
1, record 16, Spanish, polimerasa
correct, feminine noun
Record 16, Abbreviations, Spanish
Record 16, Synonyms, Spanish
Record 16, Textual support, Spanish
Record number: 16, Textual support number: 1 DEF
Enzima que parece catalizar la formación del [ADN o ARN] en la célula. 2, record 16, Spanish, - polimerasa
Record number: 16, Textual support number: 1 CONT
Las glicosilasas y polimerasas rellenan los huecos que dejan las exonucleasas y endonucleasas. 3, record 16, Spanish, - polimerasa
Record 17 - internal organization data 2004-10-20
Record 17, English
Record 17, Subject field(s)
- Chemical Engineering
- Bioengineering
Record 17, Main entry term, English
- polymerization
1, record 17, English, polymerization
correct
Record 17, Abbreviations, English
Record 17, Synonyms, English
Record 17, Textual support, English
Record number: 17, Textual support number: 1 DEF
Reaction in which a molecular weight is produced by successive additions to or condensations of a simpler compound; e. g., polystyrene may be produced from styrene, or rubber from isoprene, or a polynucleotide from a mononucleotides. 2, record 17, English, - polymerization
Record number: 17, Textual support number: 1 CONT
Any of the various components of the type of mixture necessary to gel-entrap an enzyme by polymerization have the potential to denature the enzyme... The monomer, typically comprising 20 to 60% of the polymerization reaction mixture, is more likely to damage the enzyme than are the reaction initiating free radicals, which are present in low concentrations, usually 10-6M or less. While lowering the monomer concentration may result in less damage to the enzyme, it also frequently weakens the gel and decreases the amount of protein entrapped. 3, record 17, English, - polymerization
Record 17, French
Record 17, Domaine(s)
- Génie chimique
- Technique biologique
Record 17, Main entry term, French
- polymérisation
1, record 17, French, polym%C3%A9risation
correct, feminine noun
Record 17, Abbreviations, French
Record 17, Synonyms, French
Record 17, Textual support, French
Record number: 17, Textual support number: 1 DEF
Réaction chimique au cours de laquelle un nombre plus ou moins grand de molécules de faible poids moléculaire (monomères) possédant, au moins, deux groupes fonctionnels, s'unissent pour former des composés de poids moléculaire élevé (polymères). 2, record 17, French, - polym%C3%A9risation
Record number: 17, Textual support number: 1 CONT
Avec des rayonnements ionisants, il faut, pour obtenir une inactivation totale des enzymes, appliquer des doses élevées, [...] bien supérieures aux doses permettant d'obtenir une stérilisation ou radappertisation. [...] Cette propriété permet d'utiliser les radiations ionisantes (rayons gamma ou rayons cathodiques) pour stériliser des préparations enzymatiques ou encore pour accélérer certaines réactions de polymérisation dans la préparation des enzymes immobilisées. 3, record 17, French, - polym%C3%A9risation
Record 17, Spanish
Record 17, Campo(s) temático(s)
- Ingenieria química
- Bioingeniería
Record 17, Main entry term, Spanish
- polimerización
1, record 17, Spanish, polimerizaci%C3%B3n
correct, feminine noun
Record 17, Abbreviations, Spanish
Record 17, Synonyms, Spanish
Record 17, Textual support, Spanish
Record number: 17, Textual support number: 1 DEF
Reacción o serie de reacciones mediante las cuales numerosas moléculas pequeñas de un monómero son soldadas y forman moléculas gigantes de un polímero. 2, record 17, Spanish, - polimerizaci%C3%B3n
Record 18 - internal organization data 1997-03-20
Record 18, English
Record 18, Subject field(s)
- Genetics
Record 18, Main entry term, English
- DNA synthesizer
1, record 18, English, DNA%20synthesizer
correct
Record 18, Abbreviations, English
Record 18, Synonyms, English
- oligonucleotide synthesizer 1, record 18, English, oligonucleotide%20synthesizer
correct
- automated DNA synthesizer 2, record 18, English, automated%20DNA%20synthesizer
correct
Record 18, Textual support, English
Record number: 18, Textual support number: 1 DEF
An automated machine designed to synthesize short polynucleotide chains(oligonucleotides) a similar in structure to DNA. 1, record 18, English, - DNA%20synthesizer
Record number: 18, Textual support number: 1 OBS
These machines use solid-phase synthesis in which one nucleotide at a time is added on to a growing oligonucleotide chain. Each nucleotide is added using the same sequence of chemical reactions with an appropriate derivatized purine or pyrimidine base. 1, record 18, English, - DNA%20synthesizer
Record 18, French
Record 18, Domaine(s)
- Génétique
Record 18, Main entry term, French
- synthétiseur d'ADN
1, record 18, French, synth%C3%A9tiseur%20d%27ADN
correct, masculine noun
Record 18, Abbreviations, French
Record 18, Synonyms, French
Record 18, Textual support, French
Record number: 18, Textual support number: 1 DEF
Machine automatique qui permet la synthèse de polydésoxynucléotides, par additions successives, sur une chaîne en croissance, de désoxynucléotides activés chimiquement. 1, record 18, French, - synth%C3%A9tiseur%20d%27ADN
Record 18, Spanish
Record 18, Textual support, Spanish
Record 19 - internal organization data 1991-06-06
Record 19, English
Record 19, Subject field(s)
- Molecular Biology
- Biochemistry
Record 19, Main entry term, English
- unusual base
1, record 19, English, unusual%20base
correct
Record 19, Abbreviations, English
Record 19, Synonyms, English
- rare nucleotide 1, record 19, English, rare%20nucleotide
correct
Record 19, Textual support, English
Record number: 19, Textual support number: 1 CONT
("Unusual" means a base other than A, G, C, or U.) Many of the unusual bases differ from normal bases by the presence of one or more methyl(-CH3) groups. Most, if not all, of the methyl groups are enzymatically added after the nucleotides are linked together by 3’-5’ phosphodiester linkages. Very probably, the other unusual bases also arise by the enzymatic modification of a preexisting polynucleotide. The function of the unusual bases is not yet clear. They are not limited to alanine tRNA but occur in varying proportions in all tRNA molecules. Our only hint of their role is the fact that several unusual bases cannot form conventional base pairs. Some of the unusual bases may thus have the function of disruption double-helical hairpin regions, thereby exposing free keto and amino groups which can then form secondary bonds. Depending upon the specific bases, the free groups may form secondary bonds to template RNA, to a ribosome, or to the enzyme needed to attach a specific amino acid to its specific tRNA molecule. [Examples of those rare nucleotides are : Inosine, 1-methylinosine, N2-dimethylguanosine, 1-methylguanosine, Ribothymidine, Dihydrouridine and Pseudouridine]. 1, record 19, English, - unusual%20base
Record 19, French
Record 19, Domaine(s)
- Biologie moléculaire
- Biochimie
Record 19, Main entry term, French
- base rare
1, record 19, French, base%20rare
correct, feminine noun
Record 19, Abbreviations, French
Record 19, Synonyms, French
- nucléotide inhabituel 1, record 19, French, nucl%C3%A9otide%20inhabituel
correct, masculine noun
- base atypique 1, record 19, French, base%20atypique
correct, feminine noun
Record 19, Textual support, French
Record number: 19, Textual support number: 1 CONT
Les deux classes de bases trouvées dans tous les mononucléotides sont dérivées de corps aromatiques hétérocycliques appelés purine et pyrimidine. La purine dérive elle-même de la pyrimidine par la fusion d'un cycle pyrimidine et imidazole. Les trois bases pyrimidiques les plus communes sont : l'uracile, la thymine et la cytosine, désignées couramment par U, T et C respectivement. Les bases puriques intervenant le plus souvent comme composantes des mononucléotides sont l'adénine et la guanine, respectivement désignées par A et G. Il existe [aussi] de nombreuses bases rares, telles que la 5-méthylcytosine, ou la 5-hydroxyméthyl-cytosine, [l'ionosine, la pseudouridine, etc...] Le rôle de ces bases rares n'est pas clair pour l'instant. Elles (...) existent en proportions variables dans toutes les molécules de tARN. Seul indice connu sur leur rôle possible, ces bases rares ne peuvent pas s'apparier de la manière habituelle. Certaines de ces bases rares pourraient donc avoir pour fonction de provoquer l'ouverture de quelques régions en épingle à cheveux de la double hélice, exposant ainsi des groupements cétones et aminés libres susceptibles de former des liaisons secondaires. Selon la nature des bases exposées, ces groupements libres pourraient former des liaisons secondaires avec la matrice d'ARN, avec le ribosome ou avec l'enzyme qui attache l'acide aminé à son tARN spécifique. 1, record 19, French, - base%20rare
Record 19, Spanish
Record 19, Textual support, Spanish
Record 20 - internal organization data 1990-03-02
Record 20, English
Record 20, Subject field(s)
- Genetics
Record 20, Main entry term, English
- open-circle DNA
1, record 20, English, open%2Dcircle%20DNA
correct
Record 20, Abbreviations, English
Record 20, Synonyms, English
- relaxed circular DNA 2, record 20, English, relaxed%20circular%20DNA
correct
- open circle 2, record 20, English, open%20circle
correct
Record 20, Textual support, English
Record number: 20, Textual support number: 1 DEF
A covalently joined polynucleotide double-stranded ring structure occurring in bacterial cells in which one strand is ’nicked’, so that the circle of that strand is broken. 1, record 20, English, - open%2Dcircle%20DNA
Record 20, French
Record 20, Domaine(s)
- Génétique
Record 20, Main entry term, French
- molécule circulaire déroulée
1, record 20, French, mol%C3%A9cule%20circulaire%20d%C3%A9roul%C3%A9e
correct, feminine noun
Record 20, Abbreviations, French
Record 20, Synonyms, French
Record 20, Textual support, French
Record number: 20, Textual support number: 1 CONT
La réplication de l'ADN circulaire commence par la croissance d'une très petite bulle de réplication dans l'ADN complètement fermé de façon covalente. Dans cette minuscule bulle, l'élongation provoque un superenroulement et se poursuit jusqu'à ce que la croissance s'arrête par suite de l'impossibilité stérique d'avoir davantage d'enroulements. Ces bulles ainsi arrêtées ne peuvent recommencer leur croissance que lorsqu'une enzyme spécifique (gyrase ou swivelase) produit une coupure dans un des brins, coupure qui relâche la molécule superenroulée en une molécule circulaire déroulée. Une fois la coupure réparée, la chaîne continue à croître, produisant à nouveau des superenroulements qui sont à leur tour relâchés par l'action de l'enzyme. 1, record 20, French, - mol%C3%A9cule%20circulaire%20d%C3%A9roul%C3%A9e
Record 20, Spanish
Record 20, Textual support, Spanish
Record 21 - internal organization data 1979-07-09
Record 21, English
Record 21, Subject field(s)
- Molecular Biology
Record 21, Main entry term, English
- polypeptide sequence 1, record 21, English, polypeptide%20sequence
Record 21, Abbreviations, English
Record 21, Synonyms, English
Record 21, Textual support, English
Record number: 21, Textual support number: 1 CONT
The ribosome is an intricate piece of molecular machinery designed to help translate the polynucleotide sequence of messenger RNA into the polypeptide sequence of protein. 1, record 21, English, - polypeptide%20sequence
Record 21, French
Record 21, Domaine(s)
- Biologie moléculaire
Record 21, Main entry term, French
- séquence polypeptidique 1, record 21, French, s%C3%A9quence%20polypeptidique
Record 21, Abbreviations, French
Record 21, Synonyms, French
Record 21, Textual support, French
Record number: 21, Textual support number: 1 CONT
Le ribosome est un élément complexe de la machine moléculaire dont le rôle est d'aider à la traduction de la séquence polynucléotidique de l'ARN messager en une séquence polypeptidique de protéines. 1, record 21, French, - s%C3%A9quence%20polypeptidique
Record 21, Spanish
Record 21, Textual support, Spanish
Record 22 - internal organization data 1979-07-09
Record 22, English
Record 22, Subject field(s)
- Molecular Biology
Record 22, Main entry term, English
- polynucleotide sequence 1, record 22, English, polynucleotide%20sequence
Record 22, Abbreviations, English
Record 22, Synonyms, English
Record 22, Textual support, English
Record number: 22, Textual support number: 1 CONT
The ribosome is an intricate piece of molecular machinery designed to help translate the polynucleotide sequence of messenger RNA into the polypeptide sequence of protein. 1, record 22, English, - polynucleotide%20sequence
Record 22, French
Record 22, Domaine(s)
- Biologie moléculaire
Record 22, Main entry term, French
- séquence polynucléotidique 1, record 22, French, s%C3%A9quence%20polynucl%C3%A9otidique
Record 22, Abbreviations, French
Record 22, Synonyms, French
Record 22, Textual support, French
Record number: 22, Textual support number: 1 CONT
Le ribosome est un élément complexe de la machinerie moléculaire dont le rôle est d'aider à la traduction de la séquence polynucléotidique de l'ARN messager en une séquence polypeptidique de protéines. 1, record 22, French, - s%C3%A9quence%20polynucl%C3%A9otidique
Record 22, Spanish
Record 22, Textual support, Spanish
Record 23 - internal organization data 1979-07-09
Record 23, English
Record 23, Subject field(s)
- Microbiology and Parasitology
Record 23, Main entry term, English
- fibrous polynucleotide chain 1, record 23, English, fibrous%20polynucleotide%20chain
Record 23, Abbreviations, English
Record 23, Synonyms, English
Record 23, Textual support, English
Record number: 23, Textual support number: 1 CONT
The molecules of transfer RNA form a class of small globular polynucleotide chains(as distinct from fibrous polynucleotide chains such as DNA and mRNA) about 75 to 90 nucleotides long. 1, record 23, English, - fibrous%20polynucleotide%20chain
Record 23, French
Record 23, Domaine(s)
- Microbiologie et parasitologie
Record 23, Main entry term, French
- chaîne polynucléotidique allongée 1, record 23, French, cha%C3%AEne%20polynucl%C3%A9otidique%20allong%C3%A9e
Record 23, Abbreviations, French
Record 23, Synonyms, French
Record 23, Textual support, French
Record number: 23, Textual support number: 1 CONT
Les molécules d'ARN de transfert forment une classe de petites chaînes polynucléotidiques globulaires (différant en cela des chaînes polynucléotidiques allongées que sont IADN ou le mARN) comprenant de 75 à 90 nucléotides. 1, record 23, French, - cha%C3%AEne%20polynucl%C3%A9otidique%20allong%C3%A9e
Record 23, Spanish
Record 23, Textual support, Spanish
Record 24 - internal organization data 1979-07-09
Record 24, English
Record 24, Subject field(s)
- Microbiology and Parasitology
Record 24, Main entry term, English
- globular polynucleotide chain 1, record 24, English, globular%20polynucleotide%20chain
Record 24, Abbreviations, English
Record 24, Synonyms, English
Record 24, Textual support, English
Record number: 24, Textual support number: 1 CONT
The molecules of transfer RNA form a class of small globular polynucleotide chains(...) about 75 to 90 nucleotides long. They act as vehicles for transferring amino acids from the free state inside the cell into the assembled chain of the protein. 1, record 24, English, - globular%20polynucleotide%20chain
Record 24, French
Record 24, Domaine(s)
- Microbiologie et parasitologie
Record 24, Main entry term, French
- chaîne polynucléotidique globulaire 1, record 24, French, cha%C3%AEne%20polynucl%C3%A9otidique%20globulaire
Record 24, Abbreviations, French
Record 24, Synonyms, French
Record 24, Textual support, French
Record number: 24, Textual support number: 1 CONT
Les molécules d'ARN de transfert forment une classe de petites chaînes polynucléotidiques globulaires (...) comprenant de 75 à 90 nucléotides. Ces TARN jouent le rôle de véhicules permettant le passage des acides aminés de l'état libre dans la cellule à l'état de chaîne protéique assemblée. 1, record 24, French, - cha%C3%AEne%20polynucl%C3%A9otidique%20globulaire
Record 24, Spanish
Record 24, Textual support, Spanish
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