TERMIUM Plus®
The Government of Canada’s terminology and linguistic data bank.
POLYPEPTIDE SEQUENCE [16 records]
Record 1 - internal organization data 2013-11-15
Record 1, English
Record 1, Subject field(s)
- Genetics
Record 1, Main entry term, English
- colinearity
1, record 1, English, colinearity
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
In genetics, the property that describes the linear relationship between the units of triplet sequence of nucleotides in DNA(or in RNA transcribed from it) and the corresponding sequence of amino acids in the polypeptide chain. However, some stretches of DNA molecules may not code for any peptide, and the final assembly of messenger RNA and DNA in higher organisms may require a considerable amount of processing, namely, deletion and splicing of selected segments. 1, record 1, English, - colinearity
Record 1, French
Record 1, Domaine(s)
- Génétique
Record 1, Main entry term, French
- colinéarité
1, record 1, French, colin%C3%A9arit%C3%A9
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Corrélation entre la structure linéaire du gène et la structure linéaire des protéines. Les exceptions (apparentes) sont introduites par les introns et par le cas de certains virus dont les gènes se recouvrent partiellement. 2, record 1, French, - colin%C3%A9arit%C3%A9
Record 1, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 2013-09-09
Record 2, English
Record 2, Subject field(s)
- Molecular Biology
- Cytology
Record 2, Main entry term, English
- signal peptide
1, record 2, English, signal%20peptide
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
- signal sequence 2, record 2, English, signal%20sequence
correct
Record 2, Textual support, English
Record number: 2, Textual support number: 1 DEF
A 15-to 35-amino-acid-long sequence generally at the NH2 terminus of the nascent polypeptide chains of proteins that have a destination for an intraorganellar or transmembrane location. 3, record 2, English, - signal%20peptide
Record number: 2, Textual support number: 1 OBS
Signal peptides are made in eukaryotes and prokaryotes, but not all the secreted proteins possess one. 3, record 2, English, - signal%20peptide
Record number: 2, Textual support number: 2 OBS
Not to be confused with leader peptide. 4, record 2, English, - signal%20peptide
Record 2, French
Record 2, Domaine(s)
- Biologie moléculaire
- Cytologie
Record 2, Main entry term, French
- peptide signal
1, record 2, French, peptide%20signal
correct, masculine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
- séquence signal 2, record 2, French, s%C3%A9quence%20signal
correct, feminine noun
- séquence-signal 3, record 2, French, s%C3%A9quence%2Dsignal
correct, feminine noun
Record 2, Textual support, French
Record number: 2, Textual support number: 1 DEF
Chaine peptidique d'une vingtaine d'acides aminés synthétisée au début de la traduction d'un ARN messager, destinée à être détachée de la protéine correspondante après son passage dans la citerne du réticulum endoplasmique et qui constitue un signal pour la machinerie cellulaire indiquant que cette protéine est destinée à l'exportation. 2, record 2, French, - peptide%20signal
Record number: 2, Textual support number: 1 OBS
Cette séquence riche en acides aminés hydrophobes permet à la protéine de traverser la membrane du réticulum et sert de peptide d'adressage. De telles séquences sont spécifiques des protéines qui doivent être sécrétées ou insérées dans les membranes cellulaires. 2, record 2, French, - peptide%20signal
Record number: 2, Textual support number: 2 OBS
Ne pas confondre avec peptide-leader. 4, record 2, French, - peptide%20signal
Record 2, Spanish
Record 2, Campo(s) temático(s)
- Biología molecular
- Citología
Record 2, Main entry term, Spanish
- secuencia señal
1, record 2, Spanish, secuencia%20se%C3%B1al
correct, feminine noun
Record 2, Abbreviations, Spanish
Record 2, Synonyms, Spanish
Record 2, Textual support, Spanish
Record number: 2, Textual support number: 1 DEF
Tramo de 15 a 30 residuos de aminoácidos en el extremo N-terminal de una proteína, que la capacita para ser secretada (es decir, para atravesar la membrana celular). 1, record 2, Spanish, - secuencia%20se%C3%B1al
Record number: 2, Textual support number: 1 CONT
La secuencia señal se elimina cuando la proteína se secreta. 1, record 2, Spanish, - secuencia%20se%C3%B1al
Record 3 - internal organization data 2013-01-22
Record 3, English
Record 3, Subject field(s)
- Biochemistry
Record 3, Main entry term, English
- secondary structure
1, record 3, English, secondary%20structure
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 DEF
The folding of part of a polypeptide chain into an ordered structure such as a α-helix [alpha-helix] or ß-pleated [beta-pleated] sheet; it is the result of hydrogen bonding between adjacent segments of the chain. 2, record 3, English, - secondary%20structure
Record number: 3, Textual support number: 1 CONT
Secondary structure prediction has been a reasonably successful approach in polypeptide design. Choice of amino acid sequence was aimed at achieving the proposed folding and to form a sufficient number of specific non-covalent bonds with a particular ligand. 2, record 3, English, - secondary%20structure
Record number: 3, Textual support number: 1 OBS
Although the term usually is applied to proteins, it can be applied to other polymers, e.g., the cloverleaf structure of transfer RNA. 1, record 3, English, - secondary%20structure
Record number: 3, Textual support number: 2 OBS
The distinction between secondary and tertiary structure is somewhat arbitrary. 2, record 3, English, - secondary%20structure
Record 3, French
Record 3, Domaine(s)
- Biochimie
Record 3, Main entry term, French
- structure secondaire
1, record 3, French, structure%20secondaire
correct, feminine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 DEF
Élément structural d'une chaîne polypeptidique, qui peut adopter deux conformations principales, hélice α et feuillet ß, stabilisées par des liaisons hydrogène entre l'oxygène d'un carbonyle et l'hydrogène d'un amide, de même qu'entre les chaînes latérales des aminoacides. 2, record 3, French, - structure%20secondaire
Record number: 3, Textual support number: 1 CONT
Les protéines globulaires sont, en moyenne, formées d'environ 350 acides aminés et leur chaîne principale peut se replier d'innombrables façons. Le nombre de niveaux de structure différents montre à quel point la variété règne. Tout d'abord, les interactions locales entre des acides aminés voisins sont à l'origine de la formation des hélices alpha, des feuillets bêta ou d'autres types de structures secondaires; ces structures, formant des blocs assez bien définis, s'organisent en domaines; enfin la disposition des domaines les uns par rapport aux autres produit la structure tertiaire. L'existence des mêmes structures secondaires et des mêmes domaines, dans de nombreuses protéines différentes, prouve que [...] toutes ces structures semblent jouer un rôle fondamental dans l'évolution et la diversification des protéines. 3, record 3, French, - structure%20secondaire
Record 3, Spanish
Record 3, Campo(s) temático(s)
- Bioquímica
Record 3, Main entry term, Spanish
- estructura secundaria
1, record 3, Spanish, estructura%20secundaria
correct, feminine noun
Record 3, Abbreviations, Spanish
Record 3, Synonyms, Spanish
Record 3, Textual support, Spanish
Record number: 3, Textual support number: 1 DEF
Conformación tridimensional que adoptan las macromoléculas, en particular los ácidos nucleicos y los polipéptidos. 1, record 3, Spanish, - estructura%20secundaria
Record number: 3, Textual support number: 1 OBS
Su formación resulta de la acción de fuerzas no covalentes generadas por interacciones entre residuos próximos. Algunos ejemplos son la hélice alfa y la hoja plegada beta de las proteínas y los bucles en horquilla de los ácidos nucleicos. 1, record 3, Spanish, - estructura%20secundaria
Record 4 - internal organization data 2012-08-08
Record 4, English
Record 4, Subject field(s)
- Biochemistry
Record 4, Main entry term, English
- primary structure
1, record 4, English, primary%20structure
correct
Record 4, Abbreviations, English
Record 4, Synonyms, English
Record 4, Textual support, English
Record number: 4, Textual support number: 1 DEF
Sequence of amino acid residues along a polypeptide chain in a protein. 2, record 4, English, - primary%20structure
Record number: 4, Textual support number: 1 CONT
Today, the relative ease of gene sequencing is leading to an explosion in the derivation of protein primary structure by direct gene translation. This information is being stored in DNA databanks. The current problem with the design of enzymes is that we are still unable to predict reliably the three-dimensional structure adopted by a known primary structure (amino acid sequence) ... Minor changes in primary structure can result in the formation of additional intramolecular intersubunit electrostatic or hydrophobic bonds. Even a small number of these bonds can drastically increase the stability of subunit enzymes against dissociative inactivation. 3, record 4, English, - primary%20structure
Record number: 4, Textual support number: 1 OBS
It completely determines the secondary, tertiary, and quaternary structures. 2, record 4, English, - primary%20structure
Record 4, French
Record 4, Domaine(s)
- Biochimie
Record 4, Main entry term, French
- structure primaire
1, record 4, French, structure%20primaire
correct, feminine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
Record 4, Textual support, French
Record number: 4, Textual support number: 1 DEF
Dans une chaîne polypeptidique, arrangement séquentiel des acides aminés dont l'enchaînement est assuré par des liaisons peptidiques covalentes. 2, record 4, French, - structure%20primaire
Record number: 4, Textual support number: 1 CONT
La structure primaire de la molécule protéique [...] est la structure la plus importante et la plus spécifique : elle détermine les structures secondaire et tertiaire. [...] Les protéines thermostables, une fois déterminées leurs structures primaire et tertiaire, serviraient de modèles pour la construction d'enzymes qui pourraient alors être produites par génie génétique. Car si nous comprenions les principes qui donnent leur stabilité aux protéines, nous pourrions ne modifier que quelques résidus d'acides aminés de protéines connues pour les rendre stables. 2, record 4, French, - structure%20primaire
Record 4, Spanish
Record 4, Campo(s) temático(s)
- Bioquímica
Record 4, Main entry term, Spanish
- estructura primaria
1, record 4, Spanish, estructura%20primaria
correct, feminine noun
Record 4, Abbreviations, Spanish
Record 4, Synonyms, Spanish
Record 4, Textual support, Spanish
Record number: 4, Textual support number: 1 DEF
Secuencia lineal de residuos que forman un polímero, como por ejemplo, ácidos nucleicos, polisacáridos o proteínas. 2, record 4, Spanish, - estructura%20primaria
Record 5 - internal organization data 2012-04-18
Record 5, English
Record 5, Subject field(s)
- Genetics
- Molecular Biology
- Biochemistry
Record 5, Main entry term, English
- transfer RNA
1, record 5, English, transfer%20RNA
correct
Record 5, Abbreviations, English
- tRNA 1, record 5, English, tRNA
correct
Record 5, Synonyms, English
- soluble RNA 2, record 5, English, soluble%20RNA
correct
- sRNA 3, record 5, English, sRNA
correct
- sRNA 3, record 5, English, sRNA
Record 5, Textual support, English
Record number: 5, Textual support number: 1 CONT
transfer RNA. A class of small RNA's, each containing about 80 nucleotides. A tRNA molecules has two functional sites. At one of these sites, an activating enzyme adds a specific amino acid. The other functional site carries the anticodon specific for that amino acid. Each type of tRNA transfers one particular amino acid to a growing polypeptide chain as specified by the nucleotide sequence of the messenger RNA being translated. 4, record 5, English, - transfer%20RNA
Record 5, French
Record 5, Domaine(s)
- Génétique
- Biologie moléculaire
- Biochimie
Record 5, Main entry term, French
- ARN de transfert
1, record 5, French, ARN%20de%20transfert
correct, masculine noun, standardized
Record 5, Abbreviations, French
- ARNt 2, record 5, French, ARNt
correct, masculine noun, standardized
Record 5, Synonyms, French
- acide ribonucléique de transfert 3, record 5, French, acide%20ribonucl%C3%A9ique%20de%20transfert
correct, masculine noun
- ARN soluble 4, record 5, French, ARN%20soluble
correct, masculine noun, standardized
Record 5, Textual support, French
Record number: 5, Textual support number: 1 DEF
Acide ribonucléique de petite dimension comportant 70 à 90 nucléotides, dont la fonction consiste à porter un acide aminé spécifique pour la traduction d'un ARN messager au niveau des ribosomes. 5, record 5, French, - ARN%20de%20transfert
Record number: 5, Textual support number: 1 OBS
Chaque ARNt est spécifique d'un acide aminé. [Observation reproduite avec l'autorisation de l'AFNOR.] 6, record 5, French, - ARN%20de%20transfert
Record number: 5, Textual support number: 2 OBS
ARN de transfert; ARN soluble; ARNt : termes et abréviation normalisés par l'AFNOR. 7, record 5, French, - ARN%20de%20transfert
Record 5, Spanish
Record 5, Campo(s) temático(s)
- Genética
- Biología molecular
- Bioquímica
Record 5, Main entry term, Spanish
- ácido ribonucleico de transferencia
1, record 5, Spanish, %C3%A1cido%20ribonucleico%20de%20transferencia
correct, masculine noun
Record 5, Abbreviations, Spanish
- ARNt 1, record 5, Spanish, ARNt
correct, masculine noun
Record 5, Synonyms, Spanish
Record 5, Textual support, Spanish
Record number: 5, Textual support number: 1 DEF
Tipo de ARN cuyas moléculas son pequeñas, contienen de 80-100 nucleótidos, [...] formado por una sola cadena de ribonucleótidos que está doblada, [su] función es la de captar aminoácidos en el citoplasma y transportarlos a los ribosomas, colocándolos según indica la secuencia del ARNm [ácido ribonucleico mensajero] para sintetizar las proteínas. 1, record 5, Spanish, - %C3%A1cido%20ribonucleico%20de%20transferencia
Record 6 - internal organization data 2012-03-16
Record 6, English
Record 6, Subject field(s)
- Genetics
Record 6, Main entry term, English
- initiation codon
1, record 6, English, initiation%20codon
correct
Record 6, Abbreviations, English
Record 6, Synonyms, English
- start codon 2, record 6, English, start%20codon
correct
- initiator codon 3, record 6, English, initiator%20codon
correct
- chain-initiation codon 3, record 6, English, chain%2Dinitiation%20codon
correct
- chain-initiating codon 3, record 6, English, chain%2Dinitiating%20codon
correct
Record 6, Textual support, English
Record number: 6, Textual support number: 1 DEF
A codon that codes for the first amino acid in a polypeptide sequence. 3, record 6, English, - initiation%20codon
Record number: 6, Textual support number: 1 CONT
A special transfer RNA (tRNA) recognizes this codon (AUG, or rarely, GUG) and starts the chain with the amino acid methionine (met) or rarely, valine, in the cytosol of eukaryotes or with N-formyl methionine (F-met) in prokaryotes, mitochondria, and chloroplasts. A different tRNA reads AUG as met in the middle of a chain. 3, record 6, English, - initiation%20codon
Record 6, French
Record 6, Domaine(s)
- Génétique
Record 6, Main entry term, French
- codon initiateur
1, record 6, French, codon%20initiateur
correct, masculine noun
Record 6, Abbreviations, French
Record 6, Synonyms, French
- triplet d'initiation 2, record 6, French, triplet%20d%27initiation
correct, masculine noun
- codon de départ 2, record 6, French, codon%20de%20d%C3%A9part
correct, masculine noun
- codon d'initiation 3, record 6, French, codon%20d%27initiation
correct, masculine noun, standardized
Record 6, Textual support, French
Record number: 6, Textual support number: 1 DEF
Triplet qui signale le début du message génétique sur un ARNm. [Définition normalisée par l'AFNOR et reproduite avec son autorisation.] 4, record 6, French, - codon%20initiateur
Record number: 6, Textual support number: 1 OBS
La traduction de l'ARNm en protéine commence au codon d'initiation. [Observation reproduite avec l'autorisation de l'AFNOR.] 4, record 6, French, - codon%20initiateur
Record number: 6, Textual support number: 2 OBS
codon d'initiation : terme normalisé par l'AFNOR. 5, record 6, French, - codon%20initiateur
Record 6, Spanish
Record 6, Campo(s) temático(s)
- Genética
Record 6, Main entry term, Spanish
- codón iniciador
1, record 6, Spanish, cod%C3%B3n%20iniciador
masculine noun
Record 6, Abbreviations, Spanish
Record 6, Synonyms, Spanish
Record 6, Textual support, Spanish
Record 7 - internal organization data 2011-10-21
Record 7, English
Record 7, Subject field(s)
- Biological Sciences
Record 7, Main entry term, English
- chain folding
1, record 7, English, chain%20folding
correct
Record 7, Abbreviations, English
Record 7, Synonyms, English
- folding 2, record 7, English, folding
correct
Record 7, Textual support, English
Record number: 7, Textual support number: 1 CONT
Optimal application of protein engineering technology will require understanding how the amino acid sequence of a polypeptide chain specifies its spatial conformation. It is now clear that polypeptide chain folding and subunit assembly proceeds through sequential pathways involving defined intermediates. The critical amino acid instructions directing these pathways appear to be dispersed through the sequence... Very similar patterns of chain folding and domain structure can arise from different amino acid sequences that show little or no homology. The immunoglobulins are a prime example of conservation of structure despite extensive differences in amino acid sequence. 3, record 7, English, - chain%20folding
Record 7, French
Record 7, Domaine(s)
- Sciences biologiques
Record 7, Main entry term, French
- repliement des chaînes
1, record 7, French, repliement%20des%20cha%C3%AEnes
correct, masculine noun
Record 7, Abbreviations, French
Record 7, Synonyms, French
- pliage de la chaîne 2, record 7, French, pliage%20de%20la%20cha%C3%AEne
correct, masculine noun
Record 7, Textual support, French
Record number: 7, Textual support number: 1 CONT
La structure tertiaire est due aux repliements des chaînes polypeptidiques, conférant à la molécule protéinique la forme globuleuse. (...) Les protéines contiennent des régions formées d'hélices [alpha], des feuillets [bêta], des régions sans structure rigide, des repliements souvent dus à la présence de proline. (...) Un aspect particulièrement critique de l'enroulement des chaînes polypeptidiques en leur conformation native est la très grande vitesse à laquelle elle se produit biologiquement. 3, record 7, French, - repliement%20des%20cha%C3%AEnes
Record 7, Spanish
Record 7, Textual support, Spanish
Record 8 - internal organization data 2011-01-12
Record 8, English
Record 8, Subject field(s)
- Biological Sciences
- Biotechnology
Record 8, Main entry term, English
- polypeptide
1, record 8, English, polypeptide
correct
Record 8, Abbreviations, English
Record 8, Synonyms, English
Record 8, Textual support, English
Record number: 8, Textual support number: 1 DEF
Linear polymer of more than 10 amino acids that are linked by means of peptide bonds. 2, record 8, English, - polypeptide
Record number: 8, Textual support number: 1 CONT
The properties of a polypeptide are determined by the type and sequence of its constituent amino acids. 3, record 8, English, - polypeptide
Record 8, French
Record 8, Domaine(s)
- Sciences biologiques
- Biotechnologie
Record 8, Main entry term, French
- polypeptide
1, record 8, French, polypeptide
correct, masculine noun
Record 8, Abbreviations, French
Record 8, Synonyms, French
Record 8, Textual support, French
Record number: 8, Textual support number: 1 DEF
Molécule constituée par la combinaison d'amino-acides entre eux par des liaisons peptidiques et renferment plus de 10 amino-acides. 2, record 8, French, - polypeptide
Record number: 8, Textual support number: 1 CONT
L'évolution de la structure des enzymes a suivi bien des chemins, mais ils sont tous marqués par un point commun : quand une structure est efficace, elle est conservée. Et, apparemment, il n'y a pas une multitude de conformations qui permette à un site protéique d'être "actif" pour une fonction donnée, ce qui fait que le résultat final de l'évolution est le même, quelque soit le point de départ. La physico-chimie nous rappelle qu'il n'y a pas lieu d'en être trop étonnés : de multiples contraintes s'exercent aussi bien au niveau des polypeptides (enzymes) qu'au niveau des polynucléotides (leurs gènes de structure), et le respect de ces contraintes bride l'évolution. 3, record 8, French, - polypeptide
Record 8, Spanish
Record 8, Campo(s) temático(s)
- Ciencias biológicas
- Biotecnología
Record 8, Main entry term, Spanish
- polipéptido
1, record 8, Spanish, polip%C3%A9ptido
correct, masculine noun
Record 8, Abbreviations, Spanish
Record 8, Synonyms, Spanish
Record 8, Textual support, Spanish
Record number: 8, Textual support number: 1 DEF
Polímero de aminoácidos, formado de cadenas que constan de restos de aminoácidos. 2, record 8, Spanish, - polip%C3%A9ptido
Record 9 - internal organization data 1997-11-06
Record 9, English
Record 9, Subject field(s)
- Biochemistry
Record 9, Main entry term, English
- endozepine
1, record 9, English, endozepine
correct
Record 9, Abbreviations, English
Record 9, Synonyms, English
Record 9, Textual support, English
Record number: 9, Textual support number: 1 CONT
Human endozepine, an 86 amino acid polypeptide, was originally isolated from human brain tissue as a putative ligand of the benzodiazepine receptor. Complete amino acid sequencing of the human and bovine proteins revealed significant homology with the partial sequence of diazepam binding inhibitor(DBI), a protein from rat brain. Both endozepine and DBI have been shown to elicit behavioral effects, suggesting that they function as pharmacologically-active ligands of the GABA. 2, record 9, English, - endozepine
Record 9, French
Record 9, Domaine(s)
- Biochimie
Record 9, Main entry term, French
- endozépine
1, record 9, French, endoz%C3%A9pine
correct, feminine noun
Record 9, Abbreviations, French
Record 9, Synonyms, French
Record 9, Textual support, French
Record number: 9, Textual support number: 1 CONT
Compte tenu de la présence potentielle du (DBI) [diazapam-binding inhibitor] et des peptides qui lui sont apparentés (habituellement désignés sous le nom d'endozépines), on s'attendait à ce que ces peptides suscitent un grand nombre d'études neurochimiques et comportementales, à l'instar des ligands endogènes des récepteurs des opiacés. 1, record 9, French, - endoz%C3%A9pine
Record 9, Spanish
Record 9, Textual support, Spanish
Record 10 - internal organization data 1996-09-10
Record 10, English
Record 10, Subject field(s)
- Genetics
Record 10, Main entry term, English
- domain
1, record 10, English, domain
correct
Record 10, Abbreviations, English
Record 10, Synonyms, English
Record 10, Textual support, English
Record number: 10, Textual support number: 1 DEF
Any discrete, continuous part of a polypeptide sequence that can be equated with a particular function. 2, record 10, English, - domain
Record 10, French
Record 10, Domaine(s)
- Génétique
Record 10, Main entry term, French
- domaine
1, record 10, French, domaine
correct, masculine noun
Record 10, Abbreviations, French
Record 10, Synonyms, French
Record 10, Textual support, French
Record number: 10, Textual support number: 1 DEF
Région d'une séquence polypeptidique ou d'une séquence d'acide nucléique distincte d'une autre par sa structure ou sa fonction. 1, record 10, French, - domaine
Record 10, Spanish
Record 10, Textual support, Spanish
Record 11 - internal organization data 1996-05-15
Record 11, English
Record 11, Subject field(s)
- Genetics
Record 11, Main entry term, English
- DNA template
1, record 11, English, DNA%20template
correct
Record 11, Abbreviations, English
Record 11, Synonyms, English
Record 11, Textual support, English
Record number: 11, Textual support number: 1 DEF
A single-stranded DNA molecule that specifies the nucleotide sequence of a stand synthesized by a polymerase molecule. 2, record 11, English, - DNA%20template
Record number: 11, Textual support number: 1 CONT
The amino acid sequence in a polypeptide chain is determined by the DNA template that directs its synthesis via a messenger RNA intermediate. 3, record 11, English, - DNA%20template
Record 11, French
Record 11, Domaine(s)
- Génétique
Record 11, Main entry term, French
- matrice d'ADN
1, record 11, French, matrice%20d%27ADN
correct, feminine noun
Record 11, Abbreviations, French
Record 11, Synonyms, French
- matrice de DNA 2, record 11, French, matrice%20de%20DNA
correct, feminine noun
Record 11, Textual support, French
Record number: 11, Textual support number: 1 DEF
brin servant de modèle pour la synthèse d'un brin complémentaire 3, record 11, French, - matrice%20d%27ADN
Record number: 11, Textual support number: 1 CONT
Cette ADN polymérase de grande pureté se révéla incapable de produire, à partir d'une matrice d'ADN bactérien, un ADN biologiquement actif. Cet échec s'explique par le fait que l'ADN extrait d'une bactérie telle que B. subtilis constitue une matrice médiocre pour cette enzyme. Une bonne matrice serait, par exemple, le chromosome naturel ayant la forme d'une boucle à double brin d'environ un millimètre de circonférence. 1, record 11, French, - matrice%20d%27ADN
Record 11, Spanish
Record 11, Textual support, Spanish
Record 12 - internal organization data 1989-06-16
Record 12, English
Record 12, Subject field(s)
- Translation (General)
- Biochemistry
Record 12, Main entry term, English
- acid blob
1, record 12, English, acid%20blob
correct
Record 12, Abbreviations, English
Record 12, Synonyms, English
- negative noodle 1, record 12, English, negative%20noodle
correct
Record 12, Textual support, English
Record number: 12, Textual support number: 1 CONT
The DNA-binding domains appear to have well-defined structural motifs : by contrast, mutational studies of the activator domains suggest a disquieting picture of a conformationally ill-defined polypeptide that can function almost irrespective of sequence, provided only that there is a sufficient excess of acidic residues clustered or peppered about. Thus, the elegant molecular machinery that so reliably controls expression of eukaryotic polymerase II-transcribed genes relies on nearly shapeless molecular components dubbed "acid blobs" or perhaps more aptly "negative noodles". 1, record 12, English, - acid%20blob
Record 12, French
Record 12, Domaine(s)
- Traduction (Généralités)
- Biochimie
Record 12, Main entry term, French
- boule acide
1, record 12, French, boule%20acide
proposal, feminine noun
Record 12, Abbreviations, French
Record 12, Synonyms, French
- résidu acide 1, record 12, French, r%C3%A9sidu%20acide
proposal, masculine noun
- agglomérat acide 1, record 12, French, agglom%C3%A9rat%20acide
proposal, masculine noun
Record 12, Textual support, French
Record 12, Spanish
Record 12, Textual support, Spanish
Record 13 - internal organization data 1988-12-08
Record 13, English
Record 13, Subject field(s)
- Translation (General)
- Biochemistry
Record 13, Main entry term, English
- negative noodle
1, record 13, English, negative%20noodle
correct
Record 13, Abbreviations, English
Record 13, Synonyms, English
Record 13, Textual support, English
Record number: 13, Textual support number: 1 CONT
... ill-defined polypeptide that can function almost irrespective of sequence, provided only that there is a sufficient excess of acidic residues clustered or peppered about. Thus, the elegant molecular machinery... relies on nearly shapeless molecular components dubbed "acid blobs" or perhaps more aptly "negative noodles". 1, record 13, English, - negative%20noodle
Record 13, French
Record 13, Domaine(s)
- Traduction (Généralités)
- Biochimie
Record 13, Main entry term, French
- pâté négatif
1, record 13, French, p%C3%A2t%C3%A9%20n%C3%A9gatif
proposal, masculine noun
Record 13, Abbreviations, French
Record 13, Synonyms, French
- nouille négative 1, record 13, French, nouille%20n%C3%A9gative
proposal, feminine noun
- résidu acide 1, record 13, French, r%C3%A9sidu%20acide
proposal, masculine noun
- agglomérat acide 1, record 13, French, agglom%C3%A9rat%20acide
proposal, masculine noun
Record 13, Textual support, French
Record 13, Spanish
Record 13, Textual support, Spanish
Record 14 - internal organization data 1988-03-25
Record 14, English
Record 14, Subject field(s)
- Genetics
Record 14, Main entry term, English
- ochre codon
1, record 14, English, ochre%20codon
correct
Record 14, Abbreviations, English
Record 14, Synonyms, English
- ochre codon 1, record 14, English, ochre%20codon
correct
Record 14, Textual support, English
Record number: 14, Textual support number: 1 DEF
The UAA sequence in mRNA. Like the amber codon, it signals the end of protein biosynthesis. The synthesized polypeptide chain is released after the incorporation of the amino acid encoded immediately before the ochre codon. Ochre is probably the natural termination codon, and the one most widely employed by all living systems. 2, record 14, English, - ochre%20codon
Record 14, French
Record 14, Domaine(s)
- Génétique
Record 14, Main entry term, French
- codon ochre
1, record 14, French, codon%20ochre
correct, masculine noun
Record 14, Abbreviations, French
Record 14, Synonyms, French
- codon ocre 2, record 14, French, codon%20ocre
correct, masculine noun
Record 14, Textual support, French
Record number: 14, Textual support number: 1 DEF
Séquence UAA de l'ARN messager qui indique la fin de la synthèse de la chaîne polypeptidique. 3, record 14, French, - codon%20ochre
Record 14, Spanish
Record 14, Textual support, Spanish
Record 15 - internal organization data 1979-07-09
Record 15, English
Record 15, Subject field(s)
- Molecular Biology
Record 15, Main entry term, English
- polypeptide sequence 1, record 15, English, polypeptide%20sequence
Record 15, Abbreviations, English
Record 15, Synonyms, English
Record 15, Textual support, English
Record number: 15, Textual support number: 1 CONT
The ribosome is an intricate piece of molecular machinery designed to help translate the polynucleotide sequence of messenger RNA into the polypeptide sequence of protein. 1, record 15, English, - polypeptide%20sequence
Record 15, French
Record 15, Domaine(s)
- Biologie moléculaire
Record 15, Main entry term, French
- séquence polypeptidique 1, record 15, French, s%C3%A9quence%20polypeptidique
Record 15, Abbreviations, French
Record 15, Synonyms, French
Record 15, Textual support, French
Record number: 15, Textual support number: 1 CONT
Le ribosome est un élément complexe de la machine moléculaire dont le rôle est d'aider à la traduction de la séquence polynucléotidique de l'ARN messager en une séquence polypeptidique de protéines. 1, record 15, French, - s%C3%A9quence%20polypeptidique
Record 15, Spanish
Record 15, Textual support, Spanish
Record 16 - internal organization data 1979-07-09
Record 16, English
Record 16, Subject field(s)
- Molecular Biology
Record 16, Main entry term, English
- polynucleotide sequence 1, record 16, English, polynucleotide%20sequence
Record 16, Abbreviations, English
Record 16, Synonyms, English
Record 16, Textual support, English
Record number: 16, Textual support number: 1 CONT
The ribosome is an intricate piece of molecular machinery designed to help translate the polynucleotide sequence of messenger RNA into the polypeptide sequence of protein. 1, record 16, English, - polynucleotide%20sequence
Record 16, French
Record 16, Domaine(s)
- Biologie moléculaire
Record 16, Main entry term, French
- séquence polynucléotidique 1, record 16, French, s%C3%A9quence%20polynucl%C3%A9otidique
Record 16, Abbreviations, French
Record 16, Synonyms, French
Record 16, Textual support, French
Record number: 16, Textual support number: 1 CONT
Le ribosome est un élément complexe de la machinerie moléculaire dont le rôle est d'aider à la traduction de la séquence polynucléotidique de l'ARN messager en une séquence polypeptidique de protéines. 1, record 16, French, - s%C3%A9quence%20polynucl%C3%A9otidique
Record 16, Spanish
Record 16, Textual support, Spanish
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