TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 CONT

For proteins from sources not known to be allergenic, and which do not exhibit sequence homology to a known allergen, targeted serum screening may be considered.  2, record 1, English, - targeted%20serum%20screening

Record number: 1, Textual support number: 2 CONT

In targeted serum screening, human blood serum is obtained from individuals who are allergic to materials that are broadly related to the source of the gene.  3, record 1, English, - targeted%20serum%20screening

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 CONT

Pour les protéines provenant de sources non connues pour être allergéniques et qui ne présentent pas d'homologie de séquence avec un allergène connu, un criblage ciblé de sérum peut être envisagé.  1, record 1, French, - criblage%20cibl%C3%A9%20de%20s%C3%A9rum

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 DEF

The sequential correspondence of nucleotide triplets in a nucleic acid molecule which permits nucleic acid hybridization.  1, record 2, English, - sequence%20homology

Record number: 2, Textual support number: 1 CONT

Sequence homology is important in the study of mechanisms of oncogenesis and also as an indication of the evolutionary relatedness of different organisms. The concept includes viral homology.  1, record 2, English, - sequence%20homology

Record 2,  Textual support,  French

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 DEF

Recombination between specific pairs of sequences. It is responsible for the integration of phage genomes into the bacterial chromosome. The recombination event involves a specific sequence of the phage DNA and a specific sequence of the bacterial DNA. Within these sequences, there is only a short stretch of homology, necessary for the recombination event, but not sufficient for it. The enzymes involved in this event cannot recombine other pairs of(homologous or nonhomologous) sequences, but act only on the particular pair of phage and bacterial sequences.  2, record 3, English, - site%2Dspecific%20recombination

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 DEF

Recombinaison de fragments cohésifs d'ADN engendrés par des coupures nucléasiques à des sites très spécifiques. Un exemple est l'insertion d'une molécule circulaire d'ADN de lambda dans le site récepteur du chromosome d'E. coli.  2, record 3, French, - recombinaison%20%C3%A0%20des%20sites%20sp%C3%A9cifiques

Record 3,  Textual support,  Spanish

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 DEF

A collection of computer files containing the operational data of an organization.  3, record 4, English, - database

Record number: 4, Textual support number: 1 CONT

In the absence of a suitable crystal structure, computer methods must predict protein conformation from sequence. The most powerful approaches for structure prediction are based on sequence homology or a more general analogy with known crystal structures. Improvements in these methods will require access to data bases containing the basic motifs of protein architecture... The database will also enable us to extract and store tertiary motifs... These motifs can then be slotted into a model-building study when, for example, predicting the conformation of an homologous protein.  2, record 4, English, - database

Record number: 4, Textual support number: 1 OBS

The system includes not only the stored information but also the data sublanguage (DSL), a group of subroutines used to retrieve, update, insert, and delete information; and the administrator, the person responsible for the integrity of the data and programs.  3, record 4, English, - database

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 DEF

Ensemble de données automatisées, renvoyant à des unités documentaires primaires.  1, record 4, French, - base%20de%20donn%C3%A9es

Record number: 4, Textual support number: 1 CONT

L'ensemble des banques de données (séquences d'acides nucléiques, protéines, bibliographiques) actuellement en cours de développement est absolument hors de portée de microsystèmes distribués dans les laboratoires de recherche où la compétence informatique est généralement absente. [...] Des efforts importants sont en cours pour optimiser la structure des bases de données et rendre leur interrogation plus aisée et plus performante à terme.  2, record 4, French, - base%20de%20donn%C3%A9es

Record 4,  Textual support,  Spanish

Record number: 4, Textual support number: 1 DEF

Compilación ordenada de información, usualmente contenida en un sistema de computación.  2, record 4, Spanish, - base%20de%20datos

Record 5,  Textual support,  English

Record number: 5, Textual support number: 1 DEF

The site on messenger RNA at which ribosomes initiate protein synthesis.  1, record 5, English, - ribosome%20binding%20site

Record number: 5, Textual support number: 1 OBS

Very little sequence homology exists between the binding sites of different bacterial mRNAs. In fact, the only common feature is the presence of a short sequence that is complementary to part of the region close to the 3’ end of the 16S rRNA. This polypurine stretch is often known as the Shine-Dalgarno sequence.  1, record 5, English, - ribosome%20binding%20site

Record 5,  Textual support,  French

Record number: 5, Textual support number: 1 DEF

Site sur l'ARN messager dont la fonction principale est d'aligner correctement la molécule d'ARNm sur le ribosome de manière à ce que la lecture des codons se fasse en phase.  1, record 5, French, - site%20d%27attachement%20du%20ribosome

Record number: 5, Textual support number: 1 OBS

Les séquences d'attachement de ce site peuvent être déchiffrées en traitant le ribosome fixé à un ARNm par la ribonucléase qui dégrade toutes les séquences sauf celles protégées par le ribosome.  1, record 5, French, - site%20d%27attachement%20du%20ribosome

Record 5,  Textual support,  Spanish

Record number: 5, Textual support number: 1 DEF

Secuencia de nucleótidos próxima al extremo 5' de una molécula de ARNm [ácido ribonucleico mensajero] bacteriano que facilita la unión del ARNm a la subunidad ribosómica pequeña.  1, record 5, Spanish, - sitio%20de%20uni%C3%B3n%20al%20ribosoma

Record 6,  Textual support,  English

Record number: 6, Textual support number: 1 DEF

Family of small (30 - 35 residue) cysteine-rich cationic proteins found in vertebrate phagocytes (notably the azurophil granules of neutrophils) and active against bacteria, fungi and enveloped viruses.  1, record 6, English, - defensin

Record number: 6, Textual support number: 1 OBS

May constitute up to 5% of the total protein. Insect defensins have some sequence homology with the vertebrate forms.  1, record 6, English, - defensin

Record number: 6, Textual support number: 2 OBS

Usually in plural.  2, record 6, English, - defensin

Record 6,  Textual support,  French

Record number: 6, Textual support number: 1 CONT

Chez les insectes [...] en dehors de la phagocytose et de l'encapsulation, l'immunité cellulaire est réduite, les pigments respiratoires le plus souvent absents, et la défense est fondée essentiellement sur une panoplie très élaborée de peptides antibactériens (les défensines).  1, record 6, French, - d%C3%A9fensine

Record 6,  Textual support,  Spanish

Record 7,  Textual support,  English

Record number: 7, Textual support number: 1 CONT

Zinc metalloendoproteases are widely involved in the intracellular processing and degradation of proteins. Vallee and Auld showed that these enzymes isolated from bacteria of Bacillus species share the consensus amino acid sequence, HEXXH, in their active sites and that the two histidine residues in the sequence ligate the catalytic zinc ion(1, 2). According to the sequence homology, Jiang and Bond grouped known 40 amino acid sequences of zinc endoproteases into five distinct subfamilies(astacin, serratia, matrixin, snake venom, and thermolysin).  1, record 7, English, - matrixin

Record 7,  Textual support,  French

Record number: 7, Textual support number: 1 CONT

En comparant la séquence des métalloprotéinases à zinc ainsi que l'organisation topologique de leurs structures secondaires, quatre sous-familles de Metzincines ont été décrites : les matrixines[...], les astacines [...], les reprolysines-adamalysines [...] et les serralysines.  1, record 7, French, - matrixine

Record number: 7, Textual support number: 1 OBS

Sous-famille qui regroupe des protéases à zinc capables globalement de dégrader la quasi-totalité des protéines de la matrice extracellulaire (collagène, élastine, fibronectine, laminine, protéoglycane).  2, record 7, French, - matrixine

Record 7,  Textual support,  Spanish

Record 8,  Textual support,  English

Record number: 8, Textual support number: 1 CONT

Optimal application of protein engineering technology will require understanding how the amino acid sequence of a polypeptide chain specifies its spatial conformation. It is now clear that polypeptide chain folding and subunit assembly proceeds through sequential pathways involving defined intermediates. The critical amino acid instructions directing these pathways appear to be dispersed through the sequence... Very similar patterns of chain folding and domain structure can arise from different amino acid sequences that show little or no homology. The immunoglobulins are a prime example of conservation of structure despite extensive differences in amino acid sequence.  3, record 8, English, - chain%20folding

Record 8,  Textual support,  French

Record number: 8, Textual support number: 1 CONT

La structure tertiaire est due aux repliements des chaînes polypeptidiques, conférant à la molécule protéinique la forme globuleuse. (...) Les protéines contiennent des régions formées d'hélices [alpha], des feuillets [bêta], des régions sans structure rigide, des repliements souvent dus à la présence de proline. (...) Un aspect particulièrement critique de l'enroulement des chaînes polypeptidiques en leur conformation native est la très grande vitesse à laquelle elle se produit biologiquement.  3, record 8, French, - repliement%20des%20cha%C3%AEnes

Record 8,  Textual support,  Spanish

Record 9,  Textual support,  English

Record number: 9, Textual support number: 1 DEF

An HIV species related to HIV-1 but carrying different antigenic components and with differing nucleic acid composition.  1, record 9, English, - human%20T%2Dlymphotropic%20virus%20type%20IV

Record number: 9, Textual support number: 1 OBS

It shares serologic reactivity and sequence homology with simian Lentivirus SIV and infects on T4-lymphocytes expressing the CD4 phenotypic marker.  1, record 9, English, - human%20T%2Dlymphotropic%20virus%20type%20IV

Record 9,  Textual support,  French

Record 9,  Textual support,  Spanish

Record number: 9, Textual support number: 1 OBS

HTLV por sus siglas en inglés Human T-Cell Lymphotropic Virus - IV.  1, record 9, Spanish, - virus%20linfotr%C3%B3pico%20humano%20tipo%20cuatro

Record 10,  Textual support,  English

Record number: 10, Textual support number: 1 CONT

Human endozepine, an 86 amino acid polypeptide, was originally isolated from human brain tissue as a putative ligand of the benzodiazepine receptor. Complete amino acid sequencing of the human and bovine proteins revealed significant homology with the partial sequence of diazepam binding inhibitor(DBI), a protein from rat brain. Both endozepine and DBI have been shown to elicit behavioral effects, suggesting that they function as pharmacologically-active ligands of the GABA.  2, record 10, English, - endozepine

Record 10,  Textual support,  French

Record number: 10, Textual support number: 1 CONT

Compte tenu de la présence potentielle du (DBI) [diazapam-binding inhibitor] et des peptides qui lui sont apparentés (habituellement désignés sous le nom d'endozépines), on s'attendait à ce que ces peptides suscitent un grand nombre d'études neurochimiques et comportementales, à l'instar des ligands endogènes des récepteurs des opiacés.  1, record 10, French, - endoz%C3%A9pine

Record 10,  Textual support,  Spanish

Record 11,  Textual support,  English

Record number: 11, Textual support number: 1 CONT

We describe here the cloning and characterization of a cDNA encoding a protein kinase that has high sequence homology to members of the mitogen-activated protein kinase(MAPK) kinase kinase(MAPKKK or MEKK) family; this cDNA is named cATMEKK1(Arabidopsis thaliana MAP kinase or ERK kinase kinase 1).  4, record 11, English, - MAP%20kinase%2Fextracellular%20signal%2Dregulated%20kinase%2Fkinase

Record number: 11, Textual support number: 1 OBS

Proceedings of the National Academy of Sciences Volume 93, Number 02; Pages: 765-769 Plant Biology.  5, record 11, English, - MAP%20kinase%2Fextracellular%20signal%2Dregulated%20kinase%2Fkinase

Record 11,  Textual support,  French

Record 11,  Textual support,  Spanish

Record 12,  Textual support,  English

Record number: 12, Textual support number: 1 CONT

We describe here the cloning and characterization of a cDNA encoding a protein kinase that has high sequence homology to members of the mitogen-activated protein kinase(MAPK) kinase kinase(MAPKKK or MEKK) family; this cDNA is named cATMEKK1 Arabidopsis thaliana MAP kinase or ERK kinase kinase.  1, record 12, English, - mitogen%2Dactivated%20protein%20kinase%20kinase%20kinase

Record number: 12, Textual support number: 1 OBS

Proceedings of the National Academy of Sciences Volume 93, Number 02; Pages: 765-769 Plant Biology. A gene encoding a mitogen-activated protein kinase.  3, record 12, English, - mitogen%2Dactivated%20protein%20kinase%20kinase%20kinase

Record 12,  Textual support,  French

Record 12,  Textual support,  Spanish