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TARGET EFFECTIVENESS [11 records]

Record 1 2023-05-01

English

Subject field(s)
  • Medication
  • Urinary Tract
CONT

Proximal convoluted tubule diuretics. The proximal convoluted tubule is the primary site for NA+ [sodium ion] reabsorption and seems a likely site for effective diuretic action. However, the number of downstream reabsorption sites limits the effectiveness of any diuretic targeting this region. Carbonic anhydrase inhibitors are the only commonly used diuretics that particularly target this region although they are rarely used primarily as diuretics. They work by blocking the enzyme carbonic anhydrase, which acts to help reabsorb bicarbonate in the proximal tubule.

OBS

Acetazolamide is an example of a proximal diuretic.

French

Domaine(s)
  • Médicaments
  • Appareil urinaire
CONT

Les diurétiques proximaux : ce sont les inhibiteurs de l'anhydrase carbonique (acétazolamide) et les substances osmotiques (mannitol).

Spanish

Save record 1

Record 2 2023-04-21

English

Subject field(s)
  • Pharmacodynamics
CONT

Nanomedicines help to improve the biodistribution and target accumulation of chemotherapy drugs, which allows them to better balance the effectiveness and toxicity of the treatment.

Key term(s)
  • bio-distribution
  • bio-dissemination

French

Domaine(s)
  • Pharmacodynamie
DEF

Distribution in vivo d'un médicament ou d'un produit à visée diagnostique après son administration.

Key term(s)
  • bio-distribution

Spanish

Save record 2

Record 3 2021-08-31

English

Subject field(s)
  • Weapon Systems
  • Energy (Physics)
CONT

To penetrate a target, KE projectiles rely on velocity and not an explosive charge.... Historical research indicates that KE projectiles are responsible for forty percent of tanks knocked out in battle. Because KE projectiles are normally fired at very high velocity, they have a very flat trajectory(flight path), a decreased time of flight, and increased hit probability. The effectiveness of KE projectiles decreases at longer ranges, since the projectiles slow down during long flights.

OBS

kinetic energy projectile; KE proj: designations officially approved by the Department of National Defence and the Canadian Forces.

French

Domaine(s)
  • Systèmes d'armes
  • Énergie (Physique)
OBS

projectile à énergie cinétique : désignation uniformisée par le Comité de terminologie française du Conseil de doctrine et de tactique de l'Armée de terre.

OBS

projectile à énergie cinétique; proj EC : désignations uniformisées par le ministère de la Défense nationale et les Forces canadiennes.

Spanish

Save record 3

Record 4 2018-09-21

English

Subject field(s)
  • Publication Titles (Armed Forces)
  • Combined Forces (Military)
  • Weapon Systems
OBS

The Joint Munitions Effectiveness Manual(JMEM) is a key reference for choosing the appropriate aircraft and weapons for a specific target and mission effect.

French

Domaine(s)
  • Titres de publications (Forces armées)
  • Interarmées
  • Systèmes d'armes
OBS

Le Manuel interarmées sur les effets des munitions est une référence clé dans la sélection des aéronefs et des armes appropriés pour une cible et un effet de mission précis.

Spanish

Save record 4

Record 5 2015-11-06

English

Subject field(s)
  • IT Security
DEF

An aspect of the assessment of the effectiveness of a target of evaluation, namely the ability of its security enforcing functions and mechanisms to work together in a way which is mutually supportive and provides and integrated and effective whole.

French

Domaine(s)
  • Sécurité des TI
DEF

Aspect de l'estimation de l'efficacité d'une cible d'évaluation qui recouvre la mesure dans laquelle les fonctions de sécurité de la cible d'évaluation coopèrent d'une manière qui les fait se soutenir mutuellement pour fournir un ensemble intégré et efficace. [Définition reproduite avec l'autorisation de l'AFNOR.]

Spanish

Save record 5

Record 6 2000-11-06

English

Subject field(s)
  • Aircraft Piloting and Navigation
  • Helicopters (Military)
CONT

TADS/PNVS comprises two independently-functioning subsystems : the TADS(Target Acquisition and Designation Sight), to enhance the battle effectiveness of the AAH helicopter, and Pilot Night-Vision Sensor(PNVS), to allow the pilot to navigate at night. It provides the helicopter crew with advanced electro-optical hardware to search out, recognize and engage enemy targets at standoff ranges during day or night and in limited adverse weather.

French

Domaine(s)
  • Pilotage et navigation aérienne
  • Hélicoptères (Militaire)
CONT

Le système d'acquisition et de désignation des cibles comprend un système de visualisation infrarouge (FLIR), une caméra TV, un système de poursuite de tache laser et un télémètre/désignateur laser; il sert aussi de capteur de vision nocturne de secours pour le pilotage. Quant au détecteur de vision nocturne du pilote, c'est un système de visualisation infrarouge articulé qui permet le vol de nuit en rase-mottes grâce à une imagerie thermique dans le viseur monoculaire du pilote.

Spanish

Save record 6

Record 7 2000-11-06

English

Subject field(s)
  • Flight Instruments and Equipment (Aeroindustry)
  • Helicopters (Military)
CONT

TADS/PNVS comprises two independently-functioning subsystems : the TADS(Target Acquisition and Designation Sight), to enhance the battle effectiveness of the AAH helicopter, and Pilot Night-Vision Sensor(PNVS), to allow the pilot to navigate at night. It provides the helicopter crew with advanced electro-optical hardware to search out, recognize and engage enemy targets at standoff ranges during day or night and in limited adverse weather.

French

Domaine(s)
  • Instruments et équipement de bord (Constructions aéronautiques)
  • Hélicoptères (Militaire)

Spanish

Save record 7

Record 8 2000-07-25

English

Subject field(s)
  • Types of Aircraft
  • Air Forces
CONT

[The] B-2 Spirit originally started as Project Senior CJ and [was] later renamed as ATB(Advance Tactical Bomber). The B-2 uses four F-118 Turbofans.... The turbofan has intake and exhaust at the top of the aircraft to prevent ground control to spot them. The pilot and co-pilot are seated side by side in a zero-zero vertically ejecting ACES II seats.... a B-2 can get updates for GPS satellites to avoid ground firing while the pilot spots the target. Once the target is found, the pilot will turn on special radar, which only scan the target area and once spotted the B-2 will launch its nuclear ordnance or SRAM II missiles.... the B-2 provides the penetrating flexibility and effectiveness inherent in manned bombers. Its low-observable, or "stealth, "characteristics give it the unique ability to penetrate an enemy's most sophisticated defenses and threaten its most-valued, and heavily defended targets. Its unrefueled range is approximately 6, 000 nautical miles(9, 600 kilometers). The B-2's low observability is derived from a combination of reduced infrared, acoustic, electromagnetic, visual and radar signatures.

French

Domaine(s)
  • Types d'aéronefs
  • Forces aériennes
CONT

Investir dans des forces aériennes de longue portée: B-2 [...]

Spanish

Save record 8

Record 9 1998-03-25

English

Subject field(s)
  • Marketing
DEF

The fraction of the target market that the firm is capable of achieving given the effectiveness of its overall marketing effort in relation to those of its current competitors, and any new competitive entrants, and in relation to the effectiveness of substitute products in competing for market share. This relationship is expressed by the fundamental theorem of market share determination.

French

Domaine(s)
  • Commercialisation

Spanish

Save record 9

Record 10 1993-12-09

English

Subject field(s)
  • Medication
  • Bioengineering
CONT

As microcapsule carriers of drugs and biological products, liposomes effectively target drugs to specific sites, reduce toxicity in drugs, increase effectiveness in vaccines, and serve as carriers for artificial blood.

French

Domaine(s)
  • Médicaments
  • Technique biologique
CONT

Les liposomes sont des particules artificielles minuscules possédant la propriété de traverser les membranes cellulaires. En les utilisant comme transporteurs de médicaments anticancéreux, une équipe de Los Angeles vient d'obtenir des résultats encourageants dans le traitement d'une tumeur redoutable observée principalement chez les malades atteints du sida : le sarcome de Kaposi. (The Lancet, 15 mai 1993).

Spanish

Save record 10

Record 11 1993-07-30

English

Subject field(s)
  • Organization Planning
  • Productivity and Profitability

French

Domaine(s)
  • Planification d'organisation
  • Productivité et rentabilité

Spanish

Save record 11

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