TERMIUM Plus®

From: Translation Bureau

On social media

Consult the Government of Canada’s terminology data bank.

TARGET ORGAN EFFECT [3 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2019-10-09

English

Subject field(s)
  • Pharmacodynamics
DEF

[The process by which] a drug molecule [accumulates] in the target organ or tissue selectively such that the concentration of the drug at the disease site is high, while its concentration in nontarget organs and tissues is low, preferably below a certain minimal level, so as to prevent any toxic effect.

French

Domaine(s)
  • Pharmacodynamie
DEF

Action qui consiste à augmenter, à l'aide d'un vecteur, la concentration d'une substance pharmacologiquement active au sein d'un site particulier de l'organisme, l'organe cible, tout en réduisant ses concentrations au sein d'autres sites.

Spanish

Campo(s) temático(s)
  • Farmacodinámica
CONT

[…] entre las aplicaciones más importantes para el uso de las nanopartículas se encuentra la vectorización de medicamentos hacia el cerebro, […] lo cual puede ayudar en el tratamiento de enfermedades como el Alzheimer o el mal de Parkinson.

OBS

[…] tradicionalmente [la tarea de] llevar una substancia activa a su diana terapéutica se adjudica a un transportador como la sangre, que tiene [el inconveniente de distribuirla] por todas partes, [debido a que] no elige a sus destinatarios. La idea de la vectorización [consiste en utilizar] la sangre como transporte [e] incluir el fármaco en unas estructuras que, al alcanzar la diana terapéutica, liberan el fármaco que contienen […]

OBS

Diana terapéutica. Sustancia localizada en cualquier parte de la célula como la membrana celular, el citoplasma o el núcleo, capaz de reconocer un fármaco y producir una respuesta celular […]

OBS

La vectorización permite la liberación controlada del principio activo y con ello se mantiene una mayor duración de las concentraciones terapéuticas, disminución de sus efectos adversos y menor dosificación del fármaco […]

Save record 1

Record 2 2012-10-15

English

Subject field(s)
  • Environmental Studies and Analyses
  • Analytical Chemistry
  • Toxicology
  • Occupational Health and Safety
DEF

A marking on material safety data sheets regarding the chemically caused effects from exposure to a material on specifically listed organs and systems such as the liver, kidneys, nervous system, lungs, skin, and eyes.

Key term(s)
  • target organ effects

French

Domaine(s)
  • Études et analyses environnementales
  • Chimie analytique
  • Toxicologie
  • Santé et sécurité au travail
OBS

Normalement employé au pluriel, en raison du contexte des fiches signalétiques (il y a manifestation de plus d'un effet).

OBS

organe cible : VABIO, 1978; MOMEC-F, 1985, vol. 40, no. 10, p. OP23.

Spanish

Campo(s) temático(s)
  • Estudios y análisis del medio ambiente
  • Química analítica
  • Toxicología
  • Salud y seguridad en el trabajo
Save record 2

Record 3 2004-09-21

English

Subject field(s)
  • Hormones
  • Biochemistry
DEF

A chemical substance released into the blood by a special group of cells in a gland to cause changes in other distant cells of the body.

OBS

Originally the term was applied to substances secreted by various endocrine glands and transported in the blood stream to the target organ on which their effect was produced; later it was applied to various substances not produced by special glands but having similar action.

French

Domaine(s)
  • Hormones
  • Biochimie
DEF

Nom générique des produits de sécrétion des glandes vasculaires sanguines, véhiculées par le sang, capables de déclencher dans les régions traversées par ce liquide, une action morphologique ou physiologique.

OBS

Au point de vue chimique, les hormones se distinguent en trois groupes : 1) celles qui dérivent du noyau stérolique (hormones sexuelles mâles et femelles, corticosurrénales); 2) celles qui sont de nature protidique ou polypeptidique (insuline, glucagon, hormones hypophysaires, parathyroïdiennes); 3) celles qui dérivent d'aminoacides (thyroxine, adrénaline).

Spanish

Campo(s) temático(s)
  • Hormonas
  • Bioquímica
DEF

Sustancia segregada por determinados órganos y transportada por la sangre hacia otros órganos para regular actividades fisiológicas tales como el crecimiento, la reproducción o el metabolismo.

Save record 3

Copyright notice for the TERMIUM Plus® data bank

© Public Services and Procurement Canada, 2026
TERMIUM Plus®, the Government of Canada's terminology and linguistic data bank
A product of the Translation Bureau

Display options

Change the order of display of the official languages of Canada
Option to display the non-official languages (Spanish or Portuguese)
Display definitions, contexts, etc., on records

Features

GCtranslate (available on the Government of Canada network only)

Use this artificial intelligence prototype to translate Government of Canada content up to and including Protected B. Available to employees of selected departments and agencies only.

Writing tools

The Language Portal’s writing tools have a new look! Easy to consult, they give you access to a wealth of information that will help you write better in English and French.

Glossaries and vocabularies

Access Translation Bureau glossaries and vocabularies.

Date Modified: