TERMIUM Plus^®

Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 CONT

One of the most important and practical applications of the emerging understanding of the role of cycles in biology is the treatment of diseases. The abnormalities associated with virtually every disease - from allergy, arthritis and asthma to cardiovascular disease and cancer - are themselves organized cyclically and, in particular, along circadian lines. The treatment of such illnesses according to daily rhythms is commonly referred to as chronotherapy. ... A growing body of evidence suggests that therapy could be improved and toxicity reduced by administering drugs at carefully selected times of day.  2, record 1, English, - chronotherapy

Record number: 1, Textual support number: 2 CONT

Chronotherapy offers a new perspective for the non-surgical treatment of breast carcinomata since it takes into account any (synchronized) rhythmic changes in the neoplastic tissue (e.g. circadian on the one hand, and also rhythms in the host’s tolerance of treatment, e.g. x-radiation, on the other.  3, record 1, English, - chronotherapy

Record number: 1, Textual support number: 3 CONT

Toward a chronotherapy of ovarian cancer with taxol. I : Basic background.  4, record 1, English, - chronotherapy

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 DEF

Traitement appliqué en fonction de la synchronisation du médicament et des rythmes de l'organisme.  2, record 1, French, - chronoth%C3%A9rapie

Record number: 1, Textual support number: 1 CONT

[Les recherches nouvelles] portent [...] sur la chronothérapie. Celle-ci peut avoir plusieurs objectifs: restaurer les rythmes biologiques altérés par la maladie (heure correcte d'administration du cortisol dans l'insuffisance corticosurrénalienne [...] par exemple); optimiser l'utilisation d'un médicament, c'est-à-dire augmenter les effets désirés et réduire les effets non désirés en jouant sur sa distribution temporelle.  3, record 1, French, - chronoth%C3%A9rapie

Record number: 1, Textual support number: 2 CONT

Conception d'une pompe programmable pour chronothérapie appliquée à la chimiothérapie.  4, record 1, French, - chronoth%C3%A9rapie

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 CONT

Paclitaxel(Taxol) is a compound originally isolated from the bark of the Pacific yew tree(Taxus brevifolia). It has been approved by the U. S. Food and Drug Administration(FDA) for treating breast and ovarian cancers as well as lung cancer and AIDS-related Kaposi's sarcoma.  1, record 2, English, - paclitaxel

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 CONT

La solution micellaire de paclitaxel est une version reformulée de l'ingrédient actif de Taxol md, médicament couramment employé contre le cancer.  1, record 2, French, - paclitaxel

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 CONT

Taxotere, an analog of taxol, is an inhibitor of depolymerisation of microtubules and is currently in Phase 1 clinical trials.(Information found in Pascal Database).  1, record 3, English, - taxotere

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 DEF

molécule d'hémisynthèse [...] apparentée au taxol et "présentant" un large spectre d'activité in vitro "qui" permet de bloquer la multiplication des cellules en stabilisant les microtubules impliqués dans la division cellulaire. Elle est synthétisée à partir d'un taxane, présent dans les aiguilles d'if européen.  1, record 3, French, - taxot%C3%A8re

Record 3,  Textual support,  Spanish