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TCLO [2 records]

Record 1 2002-02-11

English

Subject field(s)
  • Environmental Studies and Analyses
  • Toxicology
  • Air Pollution
DEF

The lowest concentration of a substance in air to which humans or animals have been exposed for any given period of time that has produced any toxic effect in humans or produced a carcinogenic, neoplastigenic or teratogenic effect in animals or humans (RTECS).

OBS

The lowest ... exposure that induces measurable toxic effects.

OBS

TC [subscript]LO.

French

Domaine(s)
  • Études et analyses environnementales
  • Toxicologie
  • Pollution de l'air
DEF

La plus faible teneur de l'air en une substance à laquelle des personnes ou des animaux ont été exposés [...] sans qu'il y ait eu d'effet toxique chez les personnes ou d'effets carcinogènes, néoplastogènes ou tératogènes chez les animaux ou les personnes.

OBS

«Teneur» a été préféré à «concentration» pour les cahiers de la collection «Enviroguide» d'Environnement Canada.

OBS

CTmin..

Spanish

Campo(s) temático(s)
  • Estudios y análisis del medio ambiente
  • Toxicología
  • Contaminación del aire
Save record 1

Record 2 1998-08-20

English

Subject field(s)
  • Toxicology
  • Occupational Health and Safety
  • Environmental Studies and Analyses
CONT

The next step, the quantitative dose-response analysis ..., includes determining the no-observed-adverse-effect-level (NOAEL) and/or the lowest-observed-adverse-effect-level (LOAEL) for each study and type of effect. Because of the limitations associated with the use of the NOAEL, the Agency is beginning to use an additional approach, the benchmark dose approach ... If the data are considered sufficient for risk assessment, and if reproductive toxicity occurs at the lowest toxic dose level (i.e., the critical effect), an RfD or RfC, based on adverse reproductive effects, could be derived.

OBS

TDL : toxic dose level. This is sometimes also abbreviated as TDLo or TCLo. [See these other records in TERMIUM, which correspond to the related concepts "toxic dose low" and to "toxic concentration low". ]

French

Domaine(s)
  • Toxicologie
  • Santé et sécurité au travail
  • Études et analyses environnementales

Spanish

Campo(s) temático(s)
  • Toxicología
  • Salud y seguridad en el trabajo
  • Estudios y análisis del medio ambiente
Save record 2

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