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TDLO [2 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2012-11-02

English

Subject field(s)
  • Environmental Studies and Analyses
  • Toxicology
  • Environmental Economics
DEF

The lowest dose of a substance, introduced by any route other than inhalation, over any given period of time and reported to produce any toxic effect in humans or to produce carcinogenic, neoplastigenic or teratogenic effects in animals or humans (RTECS).

OBS

TDLO.

Key term(s)
  • minimal toxic dose

French

Domaine(s)
  • Études et analyses environnementales
  • Toxicologie
  • Économie environnementale
DEF

La plus faible dose d'une substance, introduite par toute autre voie que l'inhalation, pendant quelque période [...] que ce soit, dont l'absorption a été signalée comme cause d'effet toxique chez des personnes ou comme cause d'effets carcinogènes, néoplastogènes ou tératogènes chez les animaux ou les personnes.

Spanish

Campo(s) temático(s)
  • Estudios y análisis del medio ambiente
  • Toxicología
  • Economía del medio ambiente
Save record 1

Record 2 1998-08-20

English

Subject field(s)
  • Toxicology
  • Occupational Health and Safety
  • Environmental Studies and Analyses
CONT

The next step, the quantitative dose-response analysis ..., includes determining the no-observed-adverse-effect-level (NOAEL) and/or the lowest-observed-adverse-effect-level (LOAEL) for each study and type of effect. Because of the limitations associated with the use of the NOAEL, the Agency is beginning to use an additional approach, the benchmark dose approach ... If the data are considered sufficient for risk assessment, and if reproductive toxicity occurs at the lowest toxic dose level (i.e., the critical effect), an RfD or RfC, based on adverse reproductive effects, could be derived.

OBS

TDL : toxic dose level. This is sometimes also abbreviated as TDLo or TCLo. [See these other records in TERMIUM, which correspond to the related concepts "toxic dose low" and to "toxic concentration low". ]

French

Domaine(s)
  • Toxicologie
  • Santé et sécurité au travail
  • Études et analyses environnementales

Spanish

Campo(s) temático(s)
  • Toxicología
  • Salud y seguridad en el trabajo
  • Estudios y análisis del medio ambiente
Save record 2

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