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Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 CONT

The activated partial thromboplastin time(APTT) is a commonly performed laboratory procedure which is used for multiple purposes including monitoring of heparin therapy, detection of coagulation factor deficiency, and detection of lupus anticoagulants. Among the hereditary coagulation deficiencies, factor VIII and factor IX are the most common. APTT reagents differ widely in both their sensitivity to factor VIII and factor IX deficiencies as well as their responsiveness.  1, record 1, English, - activated%20partial%20thromboplastin%20time%20reagent

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 OBS

Réactif utilisé pour déterminer le temps de coagulation du plasma sanguin.  2, record 1, French, - r%C3%A9actif%20pour%20la%20d%C3%A9termination%20du%20temps%20de%20thromboplastine%20partielle%20activ%C3%A9e

Record 1,  Textual support,  Spanish

Record number: 1, Textual support number: 1 OBS

Reactivo utilizado para medir el tiempo de coagulación extrínseco del plasma.  4, record 1, Spanish, - reactivo%20de%20tiempo%20de%20tromboplastina%20parcial%20activado

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 OBS

Term(s) taken from a Canadian laboratory-equipment company’s catalogue.  1, record 2, English, - thromboplastin%20IS

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 OBS

Terme(s) tiré(s) du catalogue d'une compagnie canadienne d'équipement de laboratoire.  1, record 2, French, - thromboplastine%20IS

Record 2,  Textual support,  Spanish

Record 3,  Textual support,  English

Record number: 3, Textual support number: 1 DEF

An enzyme with proteolytic activity that catalyzes the conversion of fibrinogen to fibrin during the clotting of blood. It is formed from an inactive precursor, prothrombin, in the presence of blood platelets, calcium ions and thromboplastin.  2, record 3, English, - thrombin

Record number: 3, Textual support number: 1 CONT

Under the action of thrombin, which splits off a small peptide from fibrinogen, fibrinogen is activated and starts to interact with other monomers. The end-to-end association forms long fibrin fibrils, but apparently there is also some lateral staggering and cross-linking with other fibers to form a network. As clotting progresses, aided by the blood platelets, fibrin retracts, squeezing out the serum, and the blood clot is completed.  2, record 3, English, - thrombin

Record number: 3, Textual support number: 1 OBS

Fibrinogenase and thrombase are obsolete terms.  3, record 3, English, - thrombin

Record 3,  Textual support,  French

Record number: 3, Textual support number: 1 DEF

Enzyme catalysant l'hydrolyse de la fibrinogène en fibrine, provoquant ainsi la coagulation du sang.  2, record 3, French, - thrombine

Record number: 3, Textual support number: 1 CONT

L'ensemble du processus de coagulation du sang est fort complexe. Il met en jeu des ions calcium et une dizaine de facteurs protéiques qui font l'objet d'une activation en cascade, le plus souvent par des réactions de protéolyse partielle. C'est ainsi que la thrombine, qui transforme le fibrinogène, provient elle-même de l'activation d'une glycoprotéine plasmatique, la prothrombine.  3, record 3, French, - thrombine

Record number: 3, Textual support number: 1 OBS

Thrombose, plasmase, thrombosine et fibrine-ferment sont des termes vieillis à éviter.  2, record 3, French, - thrombine

Record 3,  Textual support,  Spanish

Record number: 3, Textual support number: 1 DEF

Enzima proteolítica que hidroliza específicamente enlaces peptídicos con L-arginina. Convierte fibrinógeno en fibrina y se forma a partir del precursor inactivo protrombina.  2, record 3, Spanish, - trombina

Record 4,  Textual support,  English

Record number: 4, Textual support number: 1 CONT

A system of standardizing the PT [prothrombin time] in oral anticoagulant control was introduced by the World Health Organization in 1983. It is based upon the determination of an International Normalized Ratio(INR) which provides a common basis for communications of PT results and interpretations of therapeutic ranges. The INR is derived from calibrations of commercial thromboplastin reagents against a sensitive human brain thromboplastin, the International Reference Preparation(IRP).  1, record 4, English, - International%20Normalized%20Ratio

Record 4,  Textual support,  French

Record number: 4, Textual support number: 1 CONT

Un système de standardisation des temps de prothrombine en anticoagulothérapie par voie orale a été institué par l'Organisation mondiale de la santé en 1983. Il est fondé sur la détermination d'un Rapport international normalisé (RIN) qui fournit un système étalon pour communiquer les résultats du temps de prothrombine et l'interprétation des échelles thérapeutiques. Le RIN est établi par calibrations des thromboplastines commerciales avec une thromboplastine sensible de cerveau humain, la Préparation internationale de référence (PIR).  1, record 4, French, - Rapport%20international%20normalis%C3%A9

Record 4,  Textual support,  Spanish