TERMIUM Plus®
The Government of Canada’s terminology and linguistic data bank.
TRANSFORMING GENE [3 records]
Record 1 - internal organization data 2014-09-29
Record 1, English
Record 1, Subject field(s)
- Cytology
Record 1, Main entry term, English
- epidermal growth factor receptor
1, record 1, English, epidermal%20growth%20factor%20receptor
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
The protein called EGF-R sets off the chain reaction that activates the mucous gene. It binds with two molecules :transforming growth factor alpha and epidermal growth factor, which occur when tissues are inflamed by cigarette smoke, or some viruses and bacteria. 1, record 1, English, - epidermal%20growth%20factor%20receptor
Record 1, French
Record 1, Domaine(s)
- Cytologie
Record 1, Main entry term, French
- récepteur du facteur de croissance épidermique
1, record 1, French, r%C3%A9cepteur%20du%20facteur%20de%20croissance%20%C3%A9pidermique
correct, masculine noun
Record 1, Abbreviations, French
- R-EGF 1, record 1, French, R%2DEGF
correct, masculine noun
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
[...] anticorps monoclonaux qui ciblent le récepteur du facteur de croissance épidermique (R-EGF) présent à la surface d’une cellule cancéreuse. Le R-EGF envoie des signaux qui favorisent la croissance et la survie des cellules cancéreuses. 1, record 1, French, - r%C3%A9cepteur%20du%20facteur%20de%20croissance%20%C3%A9pidermique
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Citología
Record 1, Main entry term, Spanish
- receptor de factor de crecimiento epidérmico
1, record 1, Spanish, receptor%20de%20factor%20de%20crecimiento%20epid%C3%A9rmico
correct, masculine noun
Record 1, Abbreviations, Spanish
- EFGR 1, record 1, Spanish, EFGR
correct, masculine noun
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 CONT
Muchas células cancerosas tienen una proteína, conocida como receptor del factor de crecimiento epidérmico (EFGR), en su superficie, mientras que las células sanas no expresan esta proteína tan fuertemente. Conjugando, o uniendo las nanopartículas de oro a un anticuerpo contra el EFGR, llamado anti-EFGR, los investigadores pueden lograr que se unan a las células cancerígenas. 1, record 1, Spanish, - receptor%20de%20factor%20de%20crecimiento%20epid%C3%A9rmico
Record number: 1, Textual support number: 1 OBS
EFGR por sus siglas en inglés. 2, record 1, Spanish, - receptor%20de%20factor%20de%20crecimiento%20epid%C3%A9rmico
Record number: 1, Textual support number: 2 OBS
Ficha realizada en colaboración con los estudiantes del Certificado en Traducción español-inglés del Glendon College, York University, Toronto, Canada. 2, record 1, Spanish, - receptor%20de%20factor%20de%20crecimiento%20epid%C3%A9rmico
Record 2 - internal organization data 2004-02-23
Record 2, English
Record 2, Subject field(s)
- Molecular Biology
- Cancers and Oncology
Record 2, Main entry term, English
- Src
1, record 2, English, Src
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 DEF
The transforming(sarcoma inducing) gene of Rous sarcoma virus. 1, record 2, English, - Src
Record number: 2, Textual support number: 1 CONT
A strong link between Src activity and the progression of breast cancer has been established. This work should prove very useful in defining the signaling pathways through which hyperactive Src signaling leads to cancerous transformations. It will also help to identify new targets for molecular therapeutics designed to inhibit the tumor-producing effects of altered Src kinase activity. 2, record 2, English, - Src
Record number: 2, Textual support number: 1 PHR
Src activity, signaling. 2, record 2, English, - Src
Record 2, French
Record 2, Domaine(s)
- Biologie moléculaire
- Cancers et oncologie
Record 2, Main entry term, French
- src
1, record 2, French, src
correct, masculine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
On distingue les oncogènes par un symbole à trois lettres s'inspirant du type de tumeur produite ou du nom du virus, par exemple src pour sarcome, abl pour virus d'Abelson. 2, record 2, French, - src
Record number: 2, Textual support number: 2 CONT
Des études préliminaires effectuées en laboratoire ont apporté la démonstration du rôle de certaines molécules de signalisation (Src, MAPK et RAC) dans l'induction de la transition épithélium-mésenchyme (TEM). 3, record 2, French, - src
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 2002-05-16
Record 3, English
Record 3, Subject field(s)
- Genetics
- Human Diseases
Record 3, Main entry term, English
- transforming gene
1, record 3, English, transforming%20gene
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 DEF
The [gene] in a virus that is responsible for the virus’s ability to transform a cell it infects. 1, record 3, English, - transforming%20gene
Record 3, French
Record 3, Domaine(s)
- Génétique
- Maladies humaines
Record 3, Main entry term, French
- gène transformant
1, record 3, French, g%C3%A8ne%20transformant
correct, masculine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 CONT
Les gènes transformants codés par ces virus jouent avant tout un rôle essentiel dans la réplication et la multiplication virale. Ce sont de véritables gènes viraux qui n'ont pas d'homologues cellulaires, par opposition à ce que l'on rencontre chez certains oncorétrovirus d'animaux. Les mécanismes mis en jeu dans la transformation ne sont donc que le prolongement de différentes fonctions nécessaires au cycle de multiplication virale. 1, record 3, French, - g%C3%A8ne%20transformant
Record 3, Spanish
Record 3, Textual support, Spanish
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