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VINCA ALKALOID [5 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2011-02-09

English

Subject field(s)
  • Medication
Universal entry(ies)
C48H58N4O14
formula, see observation
125317-39-7
CAS number
CONT

Vinorelbine tartrate is a semi-synthetic vinca alkaloid with antitumor activity.

OBS

Active ingredient sold under the name Navelbine (Glaxo Wellcome).

OBS

Chemical formula: C48H58N4O14

French

Domaine(s)
  • Médicaments
Entrée(s) universelle(s)
C48H58N4O14
formula, see observation
125317-39-7
CAS number
CONT

Tartrate de vinorelbine. Mécanismes d'action principal. Agent cytostatique dérivé des vinca-alcaloïdes, inhibant la polymérisation de la tubuline. N'affecte les microtubules neuronaux qu'à forte concentration. Bloque la mitose en phase G2 + M.

OBS

Principe actif commercialisé sous le nom Navelbine (Glaxo Wellcome).

OBS

Formule chimique : C48H58N4O14

Spanish

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Record 2 2011-01-31

English

Subject field(s)
  • Medication
Universal entry(ies)
C46H58N4O9·H2SO4
correct, formula, see observation
DEF

The sulfate salt of a vinca alkaloid extracted from Vinca rosea L.(Apocynaceae), C46H58N4O9. H2SO4; used as an antineoplastic in the palliative treatment of lymphomas, including generalized Hodgkins’ disease, lymphosarcoma, reticulum-cell sarcoma, and advanced mycosis fungoides, and of neuroblastoma, Letterer-Siwe disease, choriocarcinoma resistant to other agents, breast carcinoma resistant to other agents, and embryonal carcinoma of the testis. Administered intraveinously. Major side effects are nausea, vomiting, and bone marrow depression.

OBS

Other names: Kyocristine; Leurocristine sulfate; Leurocristine sulfate (1:1); Leurocristine sulfate (1:1) (salt); Leurocristine, sulfate; Leurocristine, sulfate (1:1) (salt) (8CI); Lilly 37231; LCR; LEUROCRISTINE; NSC 67574; NSC67674; Oncovin; Onkovin; Vincaleukoblastine, 22-oxo-, sulfate (1:1) (salt) (9CI); Vincristine sulfate (USAN); Vincristine Sulfate (USAN); Vincristine, sulfate; Vincrisul; VCR sulfate; VINCRISTINE; 37231.

OBS

Chemical formula: C46H58N4O9·H2SO4

Key term(s)
  • vinkaleukoblastine sulfate

French

Domaine(s)
  • Médicaments
Entrée(s) universelle(s)
C46H58N4O9·H2SO4
correct, formula, see observation
DEF

Alcaloïde indolique dimère extrait de la pervenche rose (Vinca rosea) utilisé à l'état de sulfate dans le traitement d'affections néoplasiques malignes (D'après les sources b et c).

OBS

Formule chimique : C46H58N4O9·H2SO4

Spanish

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Record 3 1997-03-12

English

Subject field(s)
  • Chemical Elements and Compounds
  • Medication
DEF

The sulfate salt of a vinca alcaloid extracted from Vinca rosea (apocynaceae), C66H56N4O10.H2So4, used as an antineoplastic agent. [From DOMED,1988,1836]

OBS

Names : Vincristine sulfate. Alkaloid extracted from Vinca rosea Linn. Kyocristine; Leurocristine sulfate; Leurocristine sulfate(1 : 1) ;Leurocristine sulfate(1 : 1)(salt) ;Leurocristine, sulfate; Leurocristine, sulfate(1 : 1)(salt)(8CI) ;Lilly 37231; LCR; LEUROCRISTINE; NSC 67574; NSC67674; Oncovin; Onkovin; Vincaleukoblastine, 22-oxo-, sulfate(1 : 1)(salt)(9CI) ;Vincristine sulfate(USAN) ;Vincristine Sulfate(USAN) ;Vincristine, sulfate; Vincrisul; VCR sulfate; VINCRISTINE; 37231

French

Domaine(s)
  • Éléments et composés chimiques
  • Médicaments
OBS

Nom commercial: Vincasar PFS. Source: Pharmacia. Ingrédients médicinaux: Vincristine (Sulfate de). Commentaires: LIQ (1 mg/mL) IV. Date: 1994-03-16. DIN: 02065711. Classific. thérap.: Antinéoplasique. Nom commercial: Vincristine Sulphate. Source: Novopharm Ltd. Ingrédients médicinaux: Vincristine (Sulphate de) Commentaires: LIQ (1 mg/mL) IV Date: 1994-11-25. DIN: 02143305. Classific. thérap.: Antinéoplasique.

Spanish

Save record 3

Record 4 1993-06-30

English

Subject field(s)
  • Medication
  • Chemistry
CONT

Acute shortness of breath and severe bronchospasm have been reported following the administration of vinca alkaloids. These reactions have been encountered most frequently when the vinca alkaloid was used in combination with mitomycin-C.

French

Domaine(s)
  • Médicaments
  • Chimie
CONT

On a rapporté des réactions graves de difficultés respiratoires et de brochospasme à la suite de l'administration d'alcaloïdes de la pervenche; elles sont produites le plus fréquemment lorsque l'alcaloïde de la pervenche était utilisé avec la mitomycine-C.

Spanish

Save record 4

Record 5 1987-05-25

English

Subject field(s)
  • Medication

French

Domaine(s)
  • Médicaments

Spanish

Save record 5

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