TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

ACUTE TOXICITY ASSAY [1 record]

Record 1 2020-09-01

English

Subject field(s)
  • Toxicology
DEF

[A test] used to identify hazard potential resulting from very short exposures.

CONT

In most acute toxicity tests, each test animal is administered a single (relatively high) dose of the test substance, observed for 1 or 2 weeks for signs of treatment-related effects, then necropsied. Some acute toxicity tests (such as the "classical" LD50 [lethal dose 50] test) are designed to determine the mean lethal dose of the test substance.

CONT

Acute toxicity assay by using microbes as bioindicators is an effective tool for reflecting the impact of water pollution on organisms.

French

Domaine(s)
  • Toxicologie
CONT

Les résultats de l'essai de toxicité aigüe permettent : [d'évaluer de façon quantitative] la dose létale[, de déterminer] la nature des effets toxiques aigus[, de prévoir] les signes cliniques observés en cas de surdosage aigu chez l'homme[, de choisir] les doses à utiliser pour les épreuves de toxicité par administration répétées [et de déterminer] l'index thérapeutique [...]

Spanish

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