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APPARENT VOLUME DISTRIBUTION [2 records]

Record 1 1988-04-20

English

Subject field(s)
  • Pharmacodynamics
CONT

The apparent volume of distribution may be defined as that volume of body which would be required to contain the amount of drug in the body if it wore uniformly present in the same concentration in which it is in the blood.

OBS

There has been considerable confusion concerning the estimation and meaning of the apparent volume of distribution of a drug a principal cause of this confusion is the fact that there is no obvious relationship between the apparent and real volume of distribution of a drug. The real volume of distribution of a drug is related to body water and cannot exceed total body water ...

French

Domaine(s)
  • Pharmacodynamie
CONT

Le volume de distribution apparent est une constante de proportionnalité entre la quantité de médicament dans l'organisme et la concentration plasmatique observée à un temps donné.

OBS

Le volume de distribution ne correspond pas à la même notion que le volume de distribution apparent. Le volume de distribution apparent correspond à une constante et peut excéder le volume total d'eau corporelle tandis que le volume de distribution ne peut jamais excéder le volume total d'eau corporelle.

Spanish

Save record 1

Record 2 1984-09-25

English

Subject field(s)
  • Pharmacodynamics

French

Domaine(s)
  • Pharmacodynamie
DEF

volume virtuel dans lequel on considère un principe actif comme uniformément réparti.

OBS

Un volume de distribution identique pour deux substances ne signifie pas systématiquement une identité dans leur distribution.

Spanish

Save record 2

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