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BI-SPECIFIC ANTIBODY [1 record]

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Record 1 2014-09-24

English

Subject field(s)
  • Immunology
DEF

An antibody composed of two different binding specificities, one directed to a tumor antigen, the other to a hapten.

Key term(s)
  • bi-specific antibody

French

Domaine(s)
  • Immunologie
CONT

Bien que l'intérêt d'un anticorps ayant une spécificité différente sur chacun de ses bras soit immédiatement apparu aux chercheurs, les faibles niveaux de production, l'hétérogénéité des molécules sécrétées et les difficultés de purification ont été des freins très importants qui ont retardé le développement des anticorps bispécifiques pendant plus de 20 ans.

Key term(s)
  • anticorps bi-spécifique

Spanish

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