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BURST-PROMOTING ACTIVATOR [1 record]

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Record 1 1991-09-30

English

Subject field(s)
  • Biochemistry
DEF

Activator: a substance that renders some other substance more active, especially one that combines with an enzyme to increase its catalytic activity.

CONT

Assay of multipotent stem cells in vitro showed that the more enlarged spleens contained an increased number and concentration of mixed colony-forming units (CFU-mix) (at maximum, 11 times higher than the control). When the supernatant of cultured spleen cells was added to a serum-free bone marrow cell culture with or without erythropoietin (Epo) for detection of burst-promoting activity (BPA), it enhanced erythroid mixed colony (E-mix) formation only in the presence of Epo (p less than 0,05).

OBS

Extrait de "Acta Pathology", April 1991, 41(4), pp. 259-64.

French

Domaine(s)
  • Biochimie

Spanish

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