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CALICHEAMICIN [1 record]

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Record 1 2014-07-21

English

Subject field(s)
  • Medication
CONT

[Researchers] noted that the new compound called calicheamicin worked by destroying the DNA of cancer cells. Its mechanism of action is based on a strong reaction when it gets in contact with DNA. This reaction, known as the Bergman cyclization, results in cleaving the DNA and thus destroying the cancer cell.

French

Domaine(s)
  • Médicaments
CONT

La calichéamycine et l'espéramycine [...] sont des antibiotiques antitumoraux qui contiennent l'entité enediyne et dont l'activité pharmacologique est impressionnante (4000 fois plus actifs qu'un médicament appelé adriamycine).

Spanish

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