TERMIUM Plus®
The Government of Canada’s terminology and linguistic data bank.
CHAIN TERMINATION [1 record]
Record 1 - internal organization data 2013-11-15
Record 1, English
Record 1, Subject field(s)
- Genetics
Record 1, Main entry term, English
- polypeptide chain termination
1, record 1, English, polypeptide%20chain%20termination
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- termination of the polypeptide chain 2, record 1, English, termination%20of%20the%20polypeptide%20chain
correct
- chain termination 2, record 1, English, chain%20termination
correct
- termination 3, record 1, English, termination
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
The last step in translation, i.e. the release of the completed polypeptide from the polyribosome and disengagement of ribosomes from mRNA. It is directed by specific terminator codons (UAA, UAG and UGA) in mRNA which are recognized by special release factors. When translocation places one of the terminator codons in the ribosomal A site, the ribosome does not bind an aminoacyl tRNA-elongation factor-GTP complex. Instead it binds a release factor which activates peptidyl transferase, which then hydrolyzes the bond joining the polypeptide to tRNA in the ribosomal P site. 2, record 1, English, - polypeptide%20chain%20termination
Record 1, French
Record 1, Domaine(s)
- Génétique
Record 1, Main entry term, French
- terminaison
1, record 1, French, terminaison
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- terminaison de la chaîne peptidique 2, record 1, French, terminaison%20de%20la%20cha%C3%AEne%20peptidique
correct, feminine noun
- terminaison de la chaîne protéique 2, record 1, French, terminaison%20de%20la%20cha%C3%AEne%20prot%C3%A9ique
correct, feminine noun
- terminaison de la chaîne 2, record 1, French, terminaison%20de%20la%20cha%C3%AEne
correct, feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Dernière étape de la biosynthèse des protéines. Elle succède à l'initiation et à l'élongation. Il existe sur le mRNA 3 codons différents chargés de signaler cette terminaison UAA, UAG, et UGA. Trois protéines spécifiques appelées facteurs de libération permettent la libération du polypeptidyl-tRNA du ribosome. Ils se lient au ribosome et provoquent un déplacement du polypeptidyl-tRNA du site A sur le site P. La liaison ester entre la chaîne polypeptidique et le dernier tRNA est ensuite hydrolysée, vraisemblablement par la peptidyl transférase, dont l'action catalytique semble modifiée par la fixation des facteurs de libération. 2, record 1, French, - terminaison
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Genética
Record 1, Main entry term, Spanish
- terminación
1, record 1, Spanish, terminaci%C3%B3n
feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Copyright notice for the TERMIUM Plus® data bank
© Public Services and Procurement Canada, 2024
TERMIUM Plus®, the Government of Canada's terminology and linguistic data bank
A product of the Translation Bureau
Features
Language Portal of Canada
Access a collection of Canadian resources on all aspects of English and French, including quizzes.
Writing tools
The Language Portal’s writing tools have a new look! Easy to consult, they give you access to a wealth of information that will help you write better in English and French.
Glossaries and vocabularies
Access Translation Bureau glossaries and vocabularies.
- Date Modified: