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CLASS I ANTIGEN [1 record]
Record 1 - internal organization data 1993-03-02
Record 1, English
Record 1, Subject field(s)
- Immunology
Record 1, Main entry term, English
- class I antigen
1, record 1, English, class%20I%20antigen
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- class I MHC molecule 2, record 1, English, class%20I%20MHC%20molecule
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
(Each of) major histocompatibility antigens found on virtually every cell, human erythrocytes being the only notable exception; they are found on molecules consisting of two noncovalently bound chains. One on 44,000-dalton polymorphic glycoprotein partially embedded in the cell membrane, is determined by an MHC gene(HLA-A, -B, or -C in humans); the other, [beta]2-microglobulin, a 12,000-dalton nonopolymorphic protein, is determined by a non-MHC gene. Class I antigens are the classic histocompatibility antigens recognized during graft rejection.... 3, record 1, English, - class%20I%20antigen
Record number: 1, Textual support number: 2 DEF
Histocompatibility antigen composed of two non-covalently associated, glycosylated polypeptides: a heavy chain of M. Wt. 44 000 and beta squared-microglobulin, M. Wt. 12 000. 4, record 1, English, - class%20I%20antigen
Record 1, French
Record 1, Domaine(s)
- Immunologie
Record 1, Main entry term, French
- antigène de classe I
1, record 1, French, antig%C3%A8ne%20de%20classe%20I
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- CMH de classe I 2, record 1, French, CMH%20de%20classe%20I
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Différentes approches ont permis de définir deux catégories d'antigènes d'histocompatibilité : les antigènes de classe I qui stimulent puis qui sont la cible de la réaction de lymphocytotoxicité due aux cellules T et les antigènes de classe II (...). (...) Les antigènes de classe I ont une distribution tissulaire ubiquitaire sur les cellules diploïdes (...). Les antigènes de classe I sont composés d'une chaîne lourde polymorphe (45 kDa) codée dans le CMH, associée à la [bêta]2-microglobuline non polymorphe qui est codée en dehors du CMH. 3, record 1, French, - antig%C3%A8ne%20de%20classe%20I
Record number: 1, Textual support number: 2 CONT
(...) la plupart des cellules cytotoxiques reconnaissent les antigènes viraux en association avec les antigènes de classe I ce qui conforte cette hypothèse, puisque ces antigènes sont présents sur la majorité des cellules. 4, record 1, French, - antig%C3%A8ne%20de%20classe%20I
Record 1, Spanish
Record 1, Textual support, Spanish
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