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HINGE REGION [1 record]
Record 1 - internal organization data 2006-05-08
Record 1, English
Record 1, Subject field(s)
- Immunology
Record 1, Main entry term, English
Record 1, Abbreviations, English
Record 1, Synonyms, English
- hinge region 2, record 1, English, hinge%20region
- joining region 3, record 1, English, joining%20region
- J region 3, record 1, English, J%20region
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
The portion of an immunoglobulin heavy chain between the Fc and Fab regions, which permits flexibility within the molecule and allows the two combining sites to operate independently. The hinge region is usually encoded by a separate exon. 1, record 1, English, - hinge
Record number: 1, Textual support number: 2 DEF
hinge region: a region in the immunoglobulin molecule particularly exposed to the action of proteinases. In immunoglobulin G, it is in the heavy chains close to the attachment of the light chains. There is flexibility in this region, and the Fab region, which binds antigens, can move such as fixation of complement. 4, record 1, English, - hinge
Record 1, French
Record 1, Domaine(s)
- Immunologie
Record 1, Main entry term, French
- charnière
1, record 1, French, charni%C3%A8re
feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- région charnière 2, record 1, French, r%C3%A9gion%20charni%C3%A8re
feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Partie de la chaîne lourde d'immunoglobuline entre le Fc et le Fab. La région charnière permet la flexibilité de la molécule et permet aux deux sites de liaison de l'immunoglobuline d'agir indépendamment. La région charnière est habituellement codée par un exon particulier. 1, record 1, French, - charni%C3%A8re
Record number: 1, Textual support number: 1 CONT
Il existe, proche du milieu des chaînes lourdes, un court segment d'environ 15 aminoacides, où se situent tous les résidus cystéine impliqués dans la formation des ponts S-S reliant les chaînes lourdes. Ce segment, appelé région charnière, ne présente pas d'homologie avec les autres domaines. 3, record 1, French, - charni%C3%A8re
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Inmunología
Record 1, Main entry term, Spanish
- región bisagra
1, record 1, Spanish, regi%C3%B3n%20bisagra
correct, feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
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