TERMIUM Plus®

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HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE [1 record]

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Record 1 1991-09-12

English

Subject field(s)
  • Biochemistry
  • Biophysics
DEF

An enzyme of the transferase class that catalyzes the reaction hypoxanthine (of guanine) + 5 - phospho - alpha - Delta - ribose I - disphosphate = inosine 5' - monophosphate (or guanasine 5' - monoiphosphate) + pyrophosphate.

French

Domaine(s)
  • Biochimie
  • Biophysique
CONT

Une modification directe du gène Hprt (hypoxanthine phosphoribosyltransférase), pour lequel il est possible de sélectionner les cellules possédant cette fonction (avec le milieu HAT : hypoxanthine-aminoptérine-thymidine) ou au contraire les cellules qui l'ont perdue (avec la 6-TG : 6-thioguanine) peut aussi être obtenue.

Spanish

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