TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

LAMININ [1 record]

Record 1 1999-10-22

English

Subject field(s)
  • Genetics
CONT

The basal lamina proteins laminin and type IV collagen possess unique biological activities that play a central role in cell proliferation, cell differentiation and tissue development. These large heterogeneous molecules are composed of three protein chains intertwined to form complex triple-helical structures containing numerous receptor binding domains. BioStratum has developed recombinant methods and clones to produced full length, biologically active, type IV collagen hains and heterotrimer laminin molecules, a major scientific advancement for such large and complex matrix molecules.

French

Domaine(s)
  • Génétique
CONT

Cinq intégrines partagent la même chaîne, [jouent un rôle dans la formation des vaisseaux],lient des ligands de la matrice extracellulaire (MEC), comme la fibronectine, l'ostéopontine, la tenascine ou encore la laminine et le collagène de type IV.

OBS

Essais cliniques en thérapie génique.

Spanish

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