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Record 1,  Textual support,  English

Record number: 1, Textual support number: 1 OBS

This is a system comprised of two enzymatic activities: one a restriction endonuclease that cuts DNA and the other, a methylase that modifies DNA at the same sequence. The idea being that the bacteria's own DNA is modified at the proper sites and hence is protected from the action of the restriction enzyme. However if foreign DNA enters the cell, such as by transformation or by a virus, that DNA is "foreign" and not correctly modified, hence it is a substrate for the restriction enzyme and is cut up into small pieces.  5, record 1, English, - restriction%2Dmodification%20system

Record number: 1, Textual support number: 2 OBS

This "enzyme system" if only found in prokaryotes.  6, record 1, English, - restriction%2Dmodification%20system

Record 1,  Textual support,  French

Record number: 1, Textual support number: 1 DEF

Système de défense des bactéries contre l'infection des bactériophages qui met en jeu deux types d'enzymes, des méthylases (enzymes de modification) et des endonucléases (enzymes de restriction).  3, record 1, French, - syst%C3%A8me%20de%20restriction%2Dmodification

Record number: 1, Textual support number: 1 OBS

Lorsque l'ADN d'un phage pénètre dans une bactérie, il est susceptible de rencontrer deux enzymes, une endonucléase (ou enzyme de restriction) et une méthylase (ou enzyme de modification). La plupart du temps c'est l'endonucléase qui agit en premier et coupe l'ADN étranger, qui se trouve ainsi détruit et devient inactif. La bactérie s'est ainsi protégée de l'infection virale.  1, record 1, French, - syst%C3%A8me%20de%20restriction%2Dmodification

Record 1,  Textual support,  Spanish

Record 2,  Textual support,  English

Record number: 2, Textual support number: 1 DEF

In bacteria, enzyme systems that determine the acceptance or rejection (restriction) of foreign DNA which has entered the cell.  2, record 2, English, - modification%2Drestriction%20system

Record number: 2, Textual support number: 1 CONT

Investigation has shown that this restriction was due to bacterial enzymes that recognize specific sites on a "foreign" viral DNA and cleave that DNA. To protect its own DNA the bacterial cell makes a modification enzyme that adds methyl groups to nucleotides constituting the recognition sites for the restriction endonuclease, making them resistant to cleavage (modification-restriction system).  2, record 2, English, - modification%2Drestriction%20system

Record 2,  Textual support,  French

Record number: 2, Textual support number: 1 DEF

Système enzymatique qui détermine si de l'ADN sera accepté ou rejeté par la cellule.  2, record 2, French, - syst%C3%A8me%20de%20restriction%2Dmodification

Record number: 2, Textual support number: 1 CONT

Il existe chez la plupart des bactéries un système dit de "restriction-modification" codé par le chromosome bactérien, des plasmides, ou même certains bactériophages.  2, record 2, French, - syst%C3%A8me%20de%20restriction%2Dmodification

Record 2,  Textual support,  Spanish