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NUCLEAR RECEPTOR [1 record]

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Record 1 2010-03-18

English

Subject field(s)
  • Molecular Biology
CONT

[Nuclear receptors provide] links between signaling molecules and the transcriptional system and they use several domains with different functions. The A/B domains are receptive to transactivation. The conserved C domains with Zn [zinc] fingers bind DNA (usually after dimerization). The D domain is a flexible hinge. The E domain binds ligands (hormones, vitamin D, etc), dimerizes, and controls transcription.

French

Domaine(s)
  • Biologie moléculaire
DEF

Facteur de transcription qui dépend d'un ligand pour son activation et se fixe sur des séquences d'ADN spécifiques appelées éléments de réponse, situés à proximité des gènes qu'il régule.

Spanish

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