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PRION [1 record]
Record 1 - internal organization data 2005-11-03
Record 1, English
Record 1, Subject field(s)
- Microbiology and Parasitology
Record 1, Main entry term, English
- proteinaceous infectious particle
1, record 1, English, proteinaceous%20infectious%20particle
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- prion 2, record 1, English, prion
correct
- PrP 3, record 1, English, PrP
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
The smallest known infectious particle, a tiny virus-like entity highly resistant to inactivation, composed entirely of a hydrophobic protein and containing no DNA or NRA. 1, record 1, English, - proteinaceous%20infectious%20particle
Record number: 1, Textual support number: 1 CONT
Its molecular weight is 50.000 or less. Isolated in 1983 from brain tissue of sheep with scrapie, prions are postulated to be the agents of scrapie and possibly of certain slow central nervous system infections of man which resemble scrapie, especially kuru and Creutzfeldt-Jakob disease. It is not known whether prions can reproduce themselves. 1, record 1, English, - proteinaceous%20infectious%20particle
Record 1, French
Record 1, Domaine(s)
- Microbiologie et parasitologie
Record 1, Main entry term, French
- prion
1, record 1, French, prion
correct, masculine noun
Record 1, Abbreviations, French
- PrP 2, record 1, French, PrP
correct, masculine noun
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Constituant principal d'une particule protéique infectieuse jouant un rôle essentiel dans la genèse de certaines maladies et ne possédant ni ARN ou ADN. 3, record 1, French, - prion
Record number: 1, Textual support number: 1 CONT
Baptisé «prion» (anagramme anglo-saxon abrégé de «particule protéique infectieuse»), le microorganisme «non conventionnel» devenait ainsi, soudainement, un véritable hérétique face au dogme sacro-saint de la biologie moléculaire, pour lequel aucune forme de vie reproductible n'est concevable sans acides nucléiques. 4, record 1, French, - prion
Record number: 1, Textual support number: 1 OBS
Comme maladie à prions, on reconnaît la tremblante du mouton ou scrapie, et chez l'humain deux maladies rares, le kuru et la maladie de Creutzfeldt-Jakob. 5, record 1, French, - prion
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Microbiología y parasitología
Record 1, Main entry term, Spanish
- prión
1, record 1, Spanish, pri%C3%B3n
correct, masculine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 OBS
De acuerdo con la hipótesis de Stanley B. Prusiner según la cual algunas proteínas pueden comportarse como agentes infecciosos. 2, record 1, Spanish, - pri%C3%B3n
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