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The Government of Canada’s terminology and linguistic data bank.
TARGET-PROTEIN [1 record]
Record 1 - internal organization data 2011-02-08
Record 1, English
Record 1, Subject field(s)
- Biochemistry
- Pharmacology
- Biotechnology
Record 1, Main entry term, English
- target protein
1, record 1, English, target%20protein
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- target-protein 2, record 1, English, target%2Dprotein
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Nearly every drug molecule works through a structural interaction with a "target" or "receptor" molecule or protein that plays key roles in all biological processes. In the most common model for this interaction, the drug molecule inserts itself into a functionally important crevice of its target protein, like a key in a lock. The molecule then binds there and either induces or, more commonly, inhibits the protein's normal function. This universal drug-target scheme suggests a powerful alternative approach to drug discovery: if it were possible to identify, in advance, the appropriate protein target for a given therapeutic need and if enough were known about the distinguishing structure of that target protein, it ought to be feasible to design the structure of an ideal drug to interact with it. 2, record 1, English, - target%20protein
Record 1, French
Record 1, Domaine(s)
- Biochimie
- Pharmacologie
- Biotechnologie
Record 1, Main entry term, French
- protéine-cible
1, record 1, French, prot%C3%A9ine%2Dcible
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
La discipline [...] «Bio-informatique du médicament» recouvre les activités suivantes : analyser et exploiter les génomes pour identifier les classes structurales et fonctionnelles d'intérêt thérapeutique; [...] modéliser les protéines-cibles dont la structure n'est pas accessible expérimentalement [...] 1, record 1, French, - prot%C3%A9ine%2Dcible
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Bioquímica
- Farmacología
- Biotecnología
Record 1, Main entry term, Spanish
- proteína diana
1, record 1, Spanish, prote%C3%ADna%20diana
correct, feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
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