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VDPV [1 record]

Record 1 2025-11-28

English

Subject field(s)
  • Microbiology and Parasitology
  • Viral Diseases
  • Immunology
CONT

What is a vaccine-derived poliovirus? A vaccine-derived poliovirus (VDPV) is a strain related to the weakened live poliovirus contained in oral polio vaccine (OPV). If allowed to circulate in under- or unimmunized populations for long enough, or replicate in an immunodeficient individual, the weakened virus can revert to a form that causes illness and paralysis.

Key term(s)
  • vaccine-derived polio virus

French

Domaine(s)
  • Microbiologie et parasitologie
  • Maladies virales
  • Immunologie
CONT

Si la souche de poliovirus présente dans le VPO [vaccin antipoliomyélitique oral] circule dans des populations à faible couverture vaccinale, ou se réplique chez un hôte immunosupprimé, elle peut subir des mutations et revenir à une forme causant une maladie paralytique qui ne se distingue pas de la polio sauvage. C'est ce qu'on appelle le poliovirus dérivé d'une souche vaccinale (PVDV).

Spanish

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