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50-76-0 [1 record]
Record 1 - internal organization data 2011-04-21
Record 1, English
Record 1, Subject field(s)
- Chemical Elements and Compounds
- Medication
Universal entry(ies) Record 1
Record 1, Main entry term, English
- dactinomycin
1, record 1, English, dactinomycin
correct, see observation
Record 1, Abbreviations, English
Record 1, Synonyms, English
- actinomycin D 1, record 1, English, actinomycin%20D
correct
- Cosmegen 2, record 1, English, Cosmegen
correct
- Meractinomycin 2, record 1, English, Meractinomycin
correct
- Oncostatin K 2, record 1, English, Oncostatin%20K
correct
- dilactone actinomycin D acid 2, record 1, English, dilactone%20actinomycin%20D%20acid
avoid
- dilactone actinomycindioic D acid 2, record 1, English, dilactone%20actinomycindioic%20D%20acid
avoid
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
An antibiotic produced by Steptomyces chrysomallus that inhibits the transcription of DNA to RNA by binding to DNA and that also has immunosuppressive activity. 3, record 1, English, - dactinomycin
Record number: 1, Textual support number: 1 CONT
Because actinomycin D inhibits RNA elongation in intact cells, as well as in cell extracts, it has become a very useful diagnostic tool for [the] identification of cell processes that depend upon RNA synthesis. 4, record 1, English, - dactinomycin
Record number: 1, Textual support number: 1 OBS
dactinomycin: International nonproprietary name (INN) of the World Health Organization (WHO). 5, record 1, English, - dactinomycin
Record number: 1, Textual support number: 2 OBS
Chemical formula: C62H86N12O16 6, record 1, English, - dactinomycin
Record 1, French
Record 1, Domaine(s)
- Éléments et composés chimiques
- Médicaments
Entrée(s) universelle(s) Record 1
Record 1, Main entry term, French
- dactinomycine
1, record 1, French, dactinomycine
correct, see observation, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- actinomycine D 2, record 1, French, actinomycine%20D
correct, feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Antibiotique antinéoplastique agissant par fixation sur la guanine du DNA, inhibant ainsi l'action de la DNA polymérase, administré par voie veineuse. 3, record 1, French, - dactinomycine
Record number: 1, Textual support number: 1 OBS
[La] forte toxicité [de la dactinomycine] pour le tissu hématopoïétique et l'épithélium digestif fait réserver son utilisation au traitement du néphroblastome, du choriocarcinome et de certains sarcomes. 3, record 1, French, - dactinomycine
Record number: 1, Textual support number: 2 OBS
dactinomycine : Dénomination commune internationale (DCI) de l'Organisation mondiale de la santé (OMS). 4, record 1, French, - dactinomycine
Record number: 1, Textual support number: 3 OBS
Formule chimique : C62H86N12O16 5, record 1, French, - dactinomycine
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Elementos y compuestos químicos
- Medicamentos
Entrada(s) universal(es) Record 1
Record 1, Main entry term, Spanish
- actinomicina D
1, record 1, Spanish, actinomicina%20D
correct, feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
- dactinomicina 2, record 1, Spanish, dactinomicina
feminine noun
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
Fármaco antibiótico antineoplásico. 3, record 1, Spanish, - actinomicina%20D
Record number: 1, Textual support number: 1 OBS
[...] utilizado en el tratamiento de tumores germinales, tumor del Wilms, sarcoma de Ewing, rabdomiosarcoma embrionario, enfermedad trofoblástica gestacional y sarcoma de Kaposi. 3, record 1, Spanish, - actinomicina%20D
Record number: 1, Textual support number: 2 OBS
Fórmula química: C62H86N12O16 4, record 1, Spanish, - actinomicina%20D
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