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61825-94-3 [1 record]
Record 1 - internal organization data 2014-09-25
Record 1, English
Record 1, Subject field(s)
- Medication
Universal entry(ies) Record 1
Record 1, Main entry term, English
- oxaliplatin
1, record 1, English, oxaliplatin
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Oxaliplatin is a platinum-based chemotherapy drug in the same family as cisplatin and carboplatin. It is typically administered in combination with fluorouracil and leucovorin in a combination known as Folfox for the treatment of colorectal cancer. Compared to cisplatin the two amine groups are replaced by cyclohexyldiamine for improved antitumour activity. The chlorine ligands are replaced by the oxalato bidentate derived from oxalic acid in order to improve water solubility. 2, record 1, English, - oxaliplatin
Record number: 1, Textual support number: 1 OBS
Active ingredient sold under a large number of commercial (trade) names, among which: Exolatin. 3, record 1, English, - oxaliplatin
Record 1, French
Record 1, Domaine(s)
- Médicaments
Entrée(s) universelle(s) Record 1
Record 1, Main entry term, French
- oxaliplatine
1, record 1, French, oxaliplatine
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
L'oxaliplatine appartient au groupe de médicaments qui combattent le cancer et que l'on appelle antinéoplasiques; elle se classe plus précisément dans le groupe d'antinéoplasiques désignés composés de platine. L'oxaliplatine prévient la croissance des cellules cancéreuses en parasitant l'action du matériel génétique (ADN) qui est nécessaire à leur reproduction. 2, record 1, French, - oxaliplatine
Record number: 1, Textual support number: 1 OBS
Principe actif commercialisé, entre autres, sous les noms de Exolatin et Exolatine. 3, record 1, French, - oxaliplatine
Record 1, Spanish
Record 1, Textual support, Spanish
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