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ALARMONE [1 record]

Record 1 2011-05-17

English

Subject field(s)
  • Biochemistry
  • Microbiology and Parasitology
  • Molecular Biology
CONT

We view ppGpp [guanosine 5'-diphosphate 3'-diphosphate] as a signal molecule which indicates to the cell an imbalance or deficiency in amino-acid supply. It is thus analogous in function to cAMP which indicates to the cell a deficiency in "fuel" availability. This type of signal molecule, which we call an alarmone (...) serves to reorient the cell's economy in response to stress in a particular area of metabolism.

French

Domaine(s)
  • Biochimie
  • Microbiologie et parasitologie
  • Biologie moléculaire
DEF

Signal biochimique hormonal qu'un organisme élabore pour répondre à une agression.

CONT

Pour Ames, un système de ce type aurait un effet général sur tous les acides aminés et jouerait le rôle d'un super-signal permettant de rétablir l'équilibre métabolique de la cellule. C'est à ce type de signal élaboré en réponse à un stress qu'il donne le nom d'alarmone.

Spanish

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