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ANGIOGENIC FACTOR [2 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2001-12-10

English

Subject field(s)
  • Molecular Biology
CONT

When angiogenic growth factors are produced in excess of angiogenesis inhibitors, the balance is tipped in favor of blood vessel growth. When inhibitors are present in excess of stimulators, angiogenesis is stopped. The normal, healthy body maintains a perfect balance of angiogenesis modulators. In general, angiogenesis is "turned off" by with more inhibitors being produced than stimulators. Tumors are known to express large amounts of angiogenic growth factors to recruit their own blood supply.

French

Domaine(s)
  • Biologie moléculaire
CONT

Chez l'homme, l'injection de facteurs de croissance angiogéniques (VEGF ou VGF) recombinants ou le transfert de leurs gènes par ADN nu ou par vecteurs viraux induit une néo-angiogénèse et une meilleure tolérance de l'ischémie.

Spanish

Save record 1

Record 2 1991-07-15

English

Subject field(s)
  • Cytology
CONT

Because of the prominent noevascularization observed in the growth of brain tumors, we studies the occurrence of basic fibroblast growth factor (bFGF) a potent angiogenic factor in astrocytomas, the most aggressive of which often have marked vascular hyperplasia. Using immunohistochemical methods, we examined 21 examples of such tumors, 7 glioblastomas multiform, 7 anaplastic astrocytomas, and 7 low grade astrocytomas. Results suggest a possible role for bFGF in tumor growth and in angiogenesis in astrocytomes.

OBS

Tiré du périodique: Cancer Research, 1990, 50 (22), 7393-7398.

French

Domaine(s)
  • Cytologie
CONT

De nombreux facteurs de croissance sont susceptibles d'induire une angiogénèse in vitro et/ou in vivo. Plusieurs d'entre eux ont pu être purifiés, séquencés et clonés. (...) Nous limiterons cette revue à certains facteurs angiogéniques (...).

OBS

Parmi les facteurs angiogéniques, on distingue l'angiotropine, la vasculotropine, le TGF (transforming growth factor), la thombine alpha, le TNF alpha et le "tumor vascular permeability factor".

Spanish

Save record 2

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