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ANTISENSE [9 records]
Record 1 - internal organization data 2016-10-26
Record 1, English
Record 1, Subject field(s)
- Biotechnology
- Genetics
Record 1, Main entry term, English
- antisense technique
1, record 1, English, antisense%20technique
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 OBS
antisense technique: term extracted from the “Glossaire de l’agriculture” and reproduced with permission of the Organisation for Economic Co-operation and Development. 2, record 1, English, - antisense%20technique
Record 1, French
Record 1, Domaine(s)
- Biotechnologie
- Génétique
Record 1, Main entry term, French
- technique antisens
1, record 1, French, technique%20antisens
feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 OBS
technique antisens : terme extrait du «Glossaire de l’agriculture» et reproduit avec l’autorisation de l’Organisation de coopération et de développement économiques. 2, record 1, French, - technique%20antisens
Record 1, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 2016-10-26
Record 2, English
Record 2, Subject field(s)
- Genetics
Record 2, Main entry term, English
- antisense gene
1, record 2, English, antisense%20gene
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 OBS
antisense gene: term extracted from the “Glossaire de l’agriculture” and reproduced with permission of the Organisation for Economic Co-operation and Development. 2, record 2, English, - antisense%20gene
Record 2, French
Record 2, Domaine(s)
- Génétique
Record 2, Main entry term, French
- gène antisens
1, record 2, French, g%C3%A8ne%20antisens
masculine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 DEF
Gène synthétique construit à partir d'un ARN [acide ribonucléique] antisens. 1, record 2, French, - g%C3%A8ne%20antisens
Record number: 2, Textual support number: 1 OBS
gène antisens : terme extrait du «Glossaire de l’agriculture» et reproduit avec l’autorisation de l’Organisation de coopération et de développement économiques. 2, record 2, French, - g%C3%A8ne%20antisens
Record 2, Spanish
Record 2, Campo(s) temático(s)
- Genética
Record 2, Main entry term, Spanish
- gen antisentido
1, record 2, Spanish, gen%20antisentido
correct, masculine noun
Record 2, Abbreviations, Spanish
Record 2, Synonyms, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 2012-11-23
Record 3, English
Record 3, Subject field(s)
- Genetics
- Molecular Biology
Record 3, Main entry term, English
- antisense RNA
1, record 3, English, antisense%20RNA
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 CONT
The strand is called the antisense strand because its sequence of nucleotides is the complement of message sense. When mRNA [messenger ribonucleic acid] forms a duplex with a complementary antisense RNA sequence, translation is blocked. 2, record 3, English, - antisense%20RNA
Record 3, Key term(s)
- anti-sense RNA
Record 3, French
Record 3, Domaine(s)
- Génétique
- Biologie moléculaire
Record 3, Main entry term, French
- ARN antisens
1, record 3, French, ARN%20antisens
correct, masculine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 DEF
ARN [acide ribonucléique] complémentaire d'un ARN messager synthétisé in vivo ou in vitro. 2, record 3, French, - ARN%20antisens
Record number: 3, Textual support number: 1 OBS
L'association de ces deux brins inhibe la traduction de l'ARNm (ARN messager). 3, record 3, French, - ARN%20antisens
Record 3, Key term(s)
- ARN anti-sens
Record 3, Spanish
Record 3, Campo(s) temático(s)
- Genética
- Biología molecular
Record 3, Main entry term, Spanish
- ARN antisentido
1, record 3, Spanish, ARN%20antisentido
correct, masculine noun
Record 3, Abbreviations, Spanish
Record 3, Synonyms, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 2012-08-20
Record 4, English
Record 4, Subject field(s)
- Genetics
Record 4, Main entry term, English
- non-coding strand
1, record 4, English, non%2Dcoding%20strand
correct
Record 4, Abbreviations, English
Record 4, Synonyms, English
- antisense strand 2, record 4, English, antisense%20strand
correct
Record 4, Textual support, English
Record number: 4, Textual support number: 1 DEF
A strand of double stranded DNA which is complementary to the coding strand, but which itself is not used as a source of information for synthesizing a molecule of protein. 1, record 4, English, - non%2Dcoding%20strand
Record 4, Key term(s)
- anti-sense strand
- non coding strand
Record 4, French
Record 4, Domaine(s)
- Génétique
Record 4, Main entry term, French
- brin non codant
1, record 4, French, brin%20non%20codant
correct, masculine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
- brin antisens 1, record 4, French, brin%20antisens
correct, masculine noun
Record 4, Textual support, French
Record number: 4, Textual support number: 1 CONT
Dans l'exemple précédent, le brin codant ou brin sens correspond au brin orienté 5' à 3', le brin antisens ou non codant correspond au brin orienté 3' à 5'. Dans l'exemple suivant, le sens de la progression de l'ARN polymérase est inversé. Dans ces conditions, le brin codant correspond au brin orienté 3' à 5' et le brin non codant correspond au brin opposé. 1, record 4, French, - brin%20non%20codant
Record 4, Key term(s)
- brin anti-sens
- brin non-codant
Record 4, Spanish
Record 4, Campo(s) temático(s)
- Genética
Record 4, Main entry term, Spanish
- cadena no codificante
1, record 4, Spanish, cadena%20no%20codificante
correct, feminine noun
Record 4, Abbreviations, Spanish
Record 4, Synonyms, Spanish
- cadena antisentido 1, record 4, Spanish, cadena%20antisentido
correct, feminine noun
Record 4, Textual support, Spanish
Record 5 - internal organization data 2009-02-09
Record 5, English
Record 5, Subject field(s)
- Medication
Record 5, Main entry term, English
- antisense drug
1, record 5, English, antisense%20drug
correct
Record 5, Abbreviations, English
Record 5, Synonyms, English
- anti-sense drug 2, record 5, English, anti%2Dsense%20drug
correct
Record 5, Textual support, English
Record number: 5, Textual support number: 1 DEF
[A drug] designed to block viral genetic instructions, marking them for destruction by cellular enzymes, in order to prevent the building of new virus or the infection of new cells. 1, record 5, English, - antisense%20drug
Record 5, French
Record 5, Domaine(s)
- Médicaments
Record 5, Main entry term, French
- médicament antisens
1, record 5, French, m%C3%A9dicament%20antisens
correct, masculine noun
Record 5, Abbreviations, French
Record 5, Synonyms, French
Record 5, Textual support, French
Record number: 5, Textual support number: 1 DEF
Médicament constitué par un enchaînement de bases choisies pour bloquer électivement les éléments d'un gène spécifique (ADN) ou de l'ARN messager correspondant. 1, record 5, French, - m%C3%A9dicament%20antisens
Record 5, Spanish
Record 5, Campo(s) temático(s)
- Medicamentos
Record 5, Main entry term, Spanish
- compuesto antisentido
1, record 5, Spanish, compuesto%20antisentido
masculine noun
Record 5, Abbreviations, Spanish
Record 5, Synonyms, Spanish
- antisentido 1, record 5, Spanish, antisentido
masculine noun
Record 5, Textual support, Spanish
Record number: 5, Textual support number: 1 DEF
Compuesto que interfiere tanto en el acoplamiento como en el desacoplamiento del ARN viral en el ADN de la célula. 1, record 5, Spanish, - compuesto%20antisentido
Record number: 5, Textual support number: 1 OBS
Actúan en macrófagos y linfocitos. 1, record 5, Spanish, - compuesto%20antisentido
Record 6 - internal organization data 2005-07-20
Record 6, English
Record 6, Subject field(s)
- Genetics
- Molecular Biology
Record 6, Main entry term, English
- antisense oligonucleotide
1, record 6, English, antisense%20oligonucleotide
correct
Record 6, Abbreviations, English
Record 6, Synonyms, English
Record 6, Textual support, English
Record number: 6, Textual support number: 1 DEF
Compound [molecule] which blocks DNA and RNA replication by presenting a string of nucleotides in the wrong direction. 1, record 6, English, - antisense%20oligonucleotide
Record 6, Key term(s)
- anti-sense oligonucleotide
- anti-sense oligo-nucleotide
- antisense oligo-nucleotide
Record 6, French
Record 6, Domaine(s)
- Génétique
- Biologie moléculaire
Record 6, Main entry term, French
- oligonucléotide antisens
1, record 6, French, oligonucl%C3%A9otide%20antisens
correct, masculine noun
Record 6, Abbreviations, French
Record 6, Synonyms, French
Record 6, Textual support, French
Record number: 6, Textual support number: 1 DEF
Molécule formée d'une courte chaîne de nucléotides dont les séquences sont disposées dans le sens contraire de celles de l'ADN ou de l'ARN pour lequel elle inhibe la réplication. 2, record 6, French, - oligonucl%C3%A9otide%20antisens
Record number: 6, Textual support number: 1 CONT
Les oligonucléotides antisens sont des segments d'ADN complémentaires d'une portion de l'ARN message du VIH (L'ARN messager est «direct», car il code directement les protéines devant être synthétisées par le ribosome). On pense qu'ils se fixent à l'ARN message viral et empêchent ainsi les ribosomes de traduire l'ARN messager en protéines virales. 1, record 6, French, - oligonucl%C3%A9otide%20antisens
Record 6, Key term(s)
- oligo-nucléotide anti-sens
- oligonucléotide anti-sens
- oligo-nucléotide antisens
Record 6, Spanish
Record 6, Campo(s) temático(s)
- Genética
- Biología molecular
Record 6, Main entry term, Spanish
- oligonucleótido antisentido
1, record 6, Spanish, oligonucle%C3%B3tido%20antisentido
correct, masculine noun
Record 6, Abbreviations, Spanish
Record 6, Synonyms, Spanish
Record 6, Textual support, Spanish
Record number: 6, Textual support number: 1 CONT
El oligonucleótido antisentido no sólo actúa sobre el ADN, sino que además interfiere con la traducción del ARN, y al unirse a la proteína, impide que ésta lleve a cabo su función. 2, record 6, Spanish, - oligonucle%C3%B3tido%20antisentido
Record number: 6, Textual support number: 2 CONT
La unión del oligonucleótido antisentido con el ARNm correspondiente por complementariedad de bases a nivel del ribosoma impide la síntesis de la proteína oncogénica. 3, record 6, Spanish, - oligonucle%C3%B3tido%20antisentido
Record 7 - internal organization data 2001-09-14
Record 7, English
Record 7, Subject field(s)
- Genetics
Record 7, Main entry term, English
- antisense strand
1, record 7, English, antisense%20strand
correct
Record 7, Abbreviations, English
Record 7, Synonyms, English
Record 7, Textual support, English
Record number: 7, Textual support number: 1 DEF
DNA strands that are not ordinarily copied by RNA in vivo but can be introduced through genetic technology; some strengthen resistance in crops. 2, record 7, English, - antisense%20strand
Record 7, French
Record 7, Domaine(s)
- Génétique
Record 7, Main entry term, French
- brin d'ADN antisens
1, record 7, French, brin%20d%27ADN%20antisens
correct, masculine noun
Record 7, Abbreviations, French
Record 7, Synonyms, French
Record 7, Textual support, French
Record number: 7, Textual support number: 1 DEF
Brin d'acide nucléique qui sert de matrice à une ARN polymérase pour la synthèse d'un ARN dont la séquence est complémentaire de celle de l'ARN portant l'information génétique. 2, record 7, French, - brin%20d%27ADN%20antisens
Record number: 7, Textual support number: 1 OBS
Il est préférable d'éviter l'emploi des termes brin codant et brin non codant qui peuvent prêter à confusion. 2, record 7, French, - brin%20d%27ADN%20antisens
Record 7, Key term(s)
- brin anti-sens
Record 7, Spanish
Record 7, Campo(s) temático(s)
- Genética
Record 7, Main entry term, Spanish
- filamento de sentido inverso
1, record 7, Spanish, filamento%20de%20sentido%20inverso
masculine noun
Record 7, Abbreviations, Spanish
Record 7, Synonyms, Spanish
Record 7, Textual support, Spanish
Record 8 - internal organization data 2001-09-14
Record 8, English
Record 8, Subject field(s)
- Genetics
Record 8, Main entry term, English
- antisense
1, record 8, English, antisense
correct, adjective
Record 8, Abbreviations, English
Record 8, Synonyms, English
Record 8, Textual support, English
Record number: 8, Textual support number: 1 DEF
In molecular genetics, referring to the strand of a double-stranded DNA that is complementary to the sense strand. 2, record 8, English, - antisense
Record number: 8, Textual support number: 1 CONT
antisense technology. 3, record 8, English, - antisense
Record number: 8, Textual support number: 1 OBS
See Conrad Lichtenstein's book "Antisense Technology: A Practical Approach". 3, record 8, English, - antisense
Record 8, French
Record 8, Domaine(s)
- Génétique
Record 8, Main entry term, French
- anti-sens
1, record 8, French, anti%2Dsens
correct, adjective
Record 8, Abbreviations, French
Record 8, Synonyms, French
Record 8, Textual support, French
Record number: 8, Textual support number: 1 CONT
Les oligonucléotides anti-sens sont des segments d'ADN complémentaires d'une portion de l'ARN messager du VIH (L'ARN messager est «direct», car il code directement les protéines devant être synthétisées par le ribosome). On pense qu'ils se fixent à l'ARN messager viral et empêchent ainsi les ribosomes de traduire l'ARN messager en protéines virales. Cependant les oligonucléotides sont rapidement dégradés par les enzymes cellulaires. Pour protéger les oligonucléotides anti-sens, on peut les renforcer en substituant un atome d'oxygène par un atome de soufre sur les liaisons phosphate entre les nucléotides. Le composé formé s'appelle phosphorothioate, résiste à la dégradation enzymatique et inhibe l'expression du VIH in vitro. 2, record 8, French, - anti%2Dsens
Record 8, Spanish
Record 8, Campo(s) temático(s)
- Genética
Record 8, Main entry term, Spanish
- de sentido inverso
1, record 8, Spanish, de%20sentido%20inverso
adjective phrase
Record 8, Abbreviations, Spanish
Record 8, Synonyms, Spanish
Record 8, Textual support, Spanish
Record 9 - internal organization data 1999-02-03
Record 9, English
Record 9, Subject field(s)
- Genetics
Record 9, Main entry term, English
- antisense sequence
1, record 9, English, antisense%20sequence
correct
Record 9, Abbreviations, English
Record 9, Synonyms, English
Record 9, Textual support, English
Record number: 9, Textual support number: 1 CONT
Probes must contain the antisense sequence (complementary to the mRNA sequence). Double-stranded probes will of course always contain the antisense sequence. When designing single-stranded probes or probe templates, be sure that the antisense strand will be synthesized. Promoters or primers used to generate single-stranded antisense probes must be located at the more 3/ end of the coding sequence. 1, record 9, English, - antisense%20sequence
Record 9, French
Record 9, Domaine(s)
- Génétique
Record 9, Main entry term, French
- séquence antisens
1, record 9, French, s%C3%A9quence%20antisens
correct, feminine noun
Record 9, Abbreviations, French
Record 9, Synonyms, French
Record 9, Textual support, French
Record number: 9, Textual support number: 1 CONT
Une autre approche développée par l'équipe de Jacques Hartzfeld de l'hôpital Paul-Brousse (Villejuif) consiste dans l'inactivation par des séquences antisens de gènes codant des facteurs maintenant les cellules souches dans un état quiescent, tels que le TGF (transforming growth factor)-ß1. 1, record 9, French, - s%C3%A9quence%20antisens
Record 9, Spanish
Record 9, Textual support, Spanish
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