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ANTISENSE OLIGO-NUCLEOTIDE [1 record]
Record 1 - internal organization data 2005-07-20
Record 1, English
Record 1, Subject field(s)
- Genetics
- Molecular Biology
Record 1, Main entry term, English
- antisense oligonucleotide
1, record 1, English, antisense%20oligonucleotide
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
Compound [molecule] which blocks DNA and RNA replication by presenting a string of nucleotides in the wrong direction. 1, record 1, English, - antisense%20oligonucleotide
Record 1, Key term(s)
- anti-sense oligonucleotide
- anti-sense oligo-nucleotide
- antisense oligo-nucleotide
Record 1, French
Record 1, Domaine(s)
- Génétique
- Biologie moléculaire
Record 1, Main entry term, French
- oligonucléotide antisens
1, record 1, French, oligonucl%C3%A9otide%20antisens
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Molécule formée d'une courte chaîne de nucléotides dont les séquences sont disposées dans le sens contraire de celles de l'ADN ou de l'ARN pour lequel elle inhibe la réplication. 2, record 1, French, - oligonucl%C3%A9otide%20antisens
Record number: 1, Textual support number: 1 CONT
Les oligonucléotides antisens sont des segments d'ADN complémentaires d'une portion de l'ARN message du VIH (L'ARN messager est «direct», car il code directement les protéines devant être synthétisées par le ribosome). On pense qu'ils se fixent à l'ARN message viral et empêchent ainsi les ribosomes de traduire l'ARN messager en protéines virales. 1, record 1, French, - oligonucl%C3%A9otide%20antisens
Record 1, Key term(s)
- oligo-nucléotide anti-sens
- oligonucléotide anti-sens
- oligo-nucléotide antisens
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Genética
- Biología molecular
Record 1, Main entry term, Spanish
- oligonucleótido antisentido
1, record 1, Spanish, oligonucle%C3%B3tido%20antisentido
correct, masculine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 CONT
El oligonucleótido antisentido no sólo actúa sobre el ADN, sino que además interfiere con la traducción del ARN, y al unirse a la proteína, impide que ésta lleve a cabo su función. 2, record 1, Spanish, - oligonucle%C3%B3tido%20antisentido
Record number: 1, Textual support number: 2 CONT
La unión del oligonucleótido antisentido con el ARNm correspondiente por complementariedad de bases a nivel del ribosoma impide la síntesis de la proteína oncogénica. 3, record 1, Spanish, - oligonucle%C3%B3tido%20antisentido
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