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CD8 [4 records]
Record 1 - internal organization data 2004-10-05
Record 1, English
Record 1, Subject field(s)
- Immunology
Record 1, Main entry term, English
- helper/suppressor ratio
1, record 1, English, helper%2Fsuppressor%20ratio
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- CD4/CD8 1, record 1, English, CD4%2FCD8
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Abnormalities in numbers of CD4+ and CD8+ T-cell subsets and the helper/suppressor ratio (CD4/CD8) were used very early in the AIDS epidemic to help define persons affected with AIDS before a screening test for HIV-1 was available. A low number of CD4+ lymphocytes alone or in combination with a decreased CD4:CD8 ratio and total lymphocyte count can be useful as a predictor of HIV-1 seropositivity and progression of disease. 1, record 1, English, - helper%2Fsuppressor%20ratio
Record 1, Key term(s)
- T8/T4 ratio
Record 1, French
Record 1, Domaine(s)
- Immunologie
Record 1, Main entry term, French
- rapport CD4/CD8
1, record 1, French, rapport%20CD4%2FCD8
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Les CD4 ou T4 sont une sorte de globules blancs, des lymphocytes qui jouent un rôle capital dans le déclenchement d'une réaction immunitaire (de défense du corps) face à un "envahisseur". Ils sont aussi la cible privilégiée des VIH. [...] On utilise parfois [...] comme indicateur le rapport CD4/CD8, ces derniers étant les éléments qui assurent la clôture d'une réaction immunitaire. 1, record 1, French, - rapport%20CD4%2FCD8
Record 1, Key term(s)
- rapport T4/T8
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Inmunología
Record 1, Main entry term, Spanish
- relación CD4/CD8
1, record 1, Spanish, relaci%C3%B3n%20CD4%2FCD8
feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
Correspondencia cuantitativa que se establece entre las células CD4 cooperadoras y las CD8 supresoras. 1, record 1, Spanish, - relaci%C3%B3n%20CD4%2FCD8
Record number: 1, Textual support number: 1 OBS
En condiciones normales, [la relación CD4/CD8] debe ser por arriba de uno, aproximadamente 2:1. En la mayoría de los casos de VIH, esta relación se encuentra invertida y es menor de uno. 1, record 1, Spanish, - relaci%C3%B3n%20CD4%2FCD8
Record 2 - internal organization data 2004-10-05
Record 2, English
Record 2, Subject field(s)
- Immunology
Record 2, Main entry term, English
- CD8
1, record 2, English, CD8
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 DEF
One type of function-determining membrane glycoprotein exists in two forms called T4 or T8 (CD4 or CD8 in another system of nomenclature); T4 molecules are on helper T cells, T8 molecules are on suppressor and cytotoxic T cells. 1, record 2, English, - CD8
Record 2, French
Record 2, Domaine(s)
- Immunologie
Record 2, Main entry term, French
- CD8
1, record 2, French, CD8
correct, see observation, masculine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
- T8 1, record 2, French, T8
masculine noun
Record 2, Textual support, French
Record number: 2, Textual support number: 1 DEF
Protéine de surface caractéristique des lymphocytes T8. 1, record 2, French, - CD8
Record number: 2, Textual support number: 1 OBS
On emploie souvent ce terme pour désigner les lymphocytes T8. 1, record 2, French, - CD8
Record 2, Spanish
Record 2, Campo(s) temático(s)
- Inmunología
Record 2, Main entry term, Spanish
- célula CD8
1, record 2, Spanish, c%C3%A9lula%20CD8
feminine noun
Record 2, Abbreviations, Spanish
Record 2, Synonyms, Spanish
- T8 citotóxica 1, record 2, Spanish, T8%20citot%C3%B3xica
feminine noun
- célula T8 supresora 1, record 2, Spanish, c%C3%A9lula%20T8%20supresora
feminine noun
Record 2, Textual support, Spanish
Record number: 2, Textual support number: 1 OBS
Célula [que] tiene la molécula CD8 en su membrana externa y que tiene por función inhibir la respuesta inmune. 1, record 2, Spanish, - c%C3%A9lula%20CD8
Record 3 - internal organization data 1993-03-24
Record 3, English
Record 3, Subject field(s)
- Lymphatic System
Record 3, Main entry term, English
- CD8 molecule 1, record 3, English, CD8%20molecule
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 CONT
Recent studies have shown that the CD4 molecule does indeed have a weak affinity for MHC class II molecules. These observations support the idea that antigen recognition by T cells involves the formation of a complex of T cell antigen receptor and CD4 or CD8 on the T cell which recognizes antigen plus MHC on another cell. 1, record 3, English, - CD8%20molecule
Record 3, French
Record 3, Domaine(s)
- Système lymphatique
Record 3, Main entry term, French
- molécule CD8
1, record 3, French, mol%C3%A9cule%20CD8
feminine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 CONT
CD4 et CD8. Les cellules T matures des organes lymphoïdes périphériques expriment l'une ou l'autre de ces deux glycoprotéines, qui déterminent la classe de molécules de CMH reconnue en association avec l'antigène : classe II pour CD4 et classe I pour CD8. De poids moléculaires respectifs de 55 kDA et 32 kDA, elles appartiennent à la superfamille des immunoglobulines. Leur rôle est incertain : augmentation de l'avidité des récepteurs [alpha][bêta] ayant une faible avidité initiale, interaction avec les molécules de CMH, activation cellulaire? 1, record 3, French, - mol%C3%A9cule%20CD8
Record 3, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 1993-03-22
Record 4, English
Record 4, Subject field(s)
- Immunology
Record 4, Main entry term, English
- T8 cell surface marker 1, record 4, English, T8%20cell%20surface%20marker
Record 4, Abbreviations, English
Record 4, Synonyms, English
- CD8 T cell surface marker 1, record 4, English, CD8%20T%20cell%20surface%20marker
Record 4, Textual support, English
Record number: 4, Textual support number: 1 CONT
T (OKT) antigens are human T cell surface markers. ... T8 (CD8) is present on cytotoxic and suppressor T cells and is involved in MHC class 1 restricted interactions. 1, record 4, English, - T8%20cell%20surface%20marker
Record 4, French
Record 4, Domaine(s)
- Immunologie
Record 4, Main entry term, French
- récepteur T8
1, record 4, French, r%C3%A9cepteur%20T8
masculine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
- récepteur CD8 1, record 4, French, r%C3%A9cepteur%20CD8
masculine noun
Record 4, Textual support, French
Record number: 4, Textual support number: 1 DEF
Récepteur des molécules de la classe I du complexe majeur d'histocompatibilité (présent à la surface des lymphocytes T). 1, record 4, French, - r%C3%A9cepteur%20T8
Record 4, Spanish
Record 4, Textual support, Spanish
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