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The Government of Canada’s terminology and linguistic data bank.
CHROMOGRANIN [4 records]
Record 1 - internal organization data 1999-03-05
Record 1, English
Record 1, Subject field(s)
- Morphology and General Physiology
- Cytology
Record 1, Main entry term, English
- chromogranin C
1, record 1, English, chromogranin%20C
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Secretoneurin: a neuropeptide generated in brain, adrenal medulla and other endocrine tissues by proteolytic processing of secretogranin II (chromogranin C) ... 2, record 1, English, - chromogranin%20C
Record 1, French
Record 1, Domaine(s)
- Morphologie et physiologie générale
- Cytologie
Record 1, Main entry term, French
- chromogranine C
1, record 1, French, chromogranine%20C
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
[...] la sécrétoneurine, un court fragment de la chromogranine C, inhibe la libération de la dopamine des neurones centraux. 1, record 1, French, - chromogranine%20C
Record number: 1, Textual support number: 1 OBS
La famille des chromogranines se compose, aujourd'hui, de six membres : les chromogranines A, B, et C, et les sécrétogranines III, IV et V (dont on n'a pas encore décodé entièrement les séquences). 1, record 1, French, - chromogranine%20C
Record 1, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 1999-03-05
Record 2, English
Record 2, Subject field(s)
- Cytology
Record 2, Main entry term, English
- chromogranin A
1, record 2, English, chromogranin%20A
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
Chromogranin A (CgA) is the prevalent member of the family of large acidic polypeptides which are stored in secretory granules of many endocrine cells. These proteins, termed the granins, are co-stored and co-released with specific hormones and neurotransmitters of a variety of endocrine cells. The intra-and extracellular functions of the granins are largely unknown, but cellular activities in which they may participate include: (I) prohormone functioning: the proteolytic processing of CgA to bioactive subproteins; (II) osmotic gradient regulation within the secretory organelles, and (III) protein sorting due to the initiated osmotic gradients and CgA's own ability to bind to other hormones. 2, record 2, English, - chromogranin%20A
Record 2, French
Record 2, Domaine(s)
- Cytologie
Record 2, Main entry term, French
- chromogranine A
1, record 2, French, chromogranine%20A
correct, feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 OBS
Nous avons découvert les propriétés bactéricides des chromogranines A : en essayant de faire produire à des bactéries génétiquement modifiées la chromogranine A humaine, nous avons constaté que toutes les bactéries disparaissaient au bout de quelques heures; la protéine produite (ou un de ses sous-produits) avait une activité antibactérienne. 2, record 2, French, - chromogranine%20A
Record number: 2, Textual support number: 2 OBS
La famille des chromogranines se compose, aujourd'hui, de six membres : les chromogranines A, B et C, et les sécrétogranines III, IV et V (dont on n'a pas encore décodé entièrement les séquences). 2, record 2, French, - chromogranine%20A
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 1999-03-05
Record 3, English
Record 3, Subject field(s)
- Morphology and General Physiology
- Cytology
Record 3, Main entry term, English
- chromogranin B
1, record 3, English, chromogranin%20B
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 CONT
Chromogranin B (secretogranin I or Scg-1) is a tyrosine-sulfated secretory protein found in a wide variety of peptidergic endocrine cells. Benedum et al. (1987) isolated a 2.5-kb cDNA clone from a cDNA library of human pheochromocytoma. Chromogranin B is a 657 amino acid long polypeptide of 76 kilodaltons and is preceded by a cleaved end-terminal signal peptide of 20 residues. Chromogranin B was assigned to chromosome 20 by Craig et al. (1986). Craig et al. (1987) showed by in situ hybridization that the CHGB locus is on 20pter-p12. Jenkins et al. (1991) mapped the murine gene, symbolized Scg-1, to chromosome 2 by in situ hybridization and by interspecific backcross analysis. 2, record 3, English, - chromogranin%20B
Record 3, French
Record 3, Domaine(s)
- Morphologie et physiologie générale
- Cytologie
Record 3, Main entry term, French
- chromogranine B
1, record 3, French, chromogranine%20B
correct, feminine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 CONT
Le peptide correspondant à la séquence C-terminale de la chromogranine B a une activité lytique sélective contre la bactérie Micrococcus luteus à des concentrations infimes [...] 2, record 3, French, - chromogranine%20B
Record 3, Spanish
Record 3, Textual support, Spanish
Record 4 - internal organization data 1999-03-05
Record 4, English
Record 4, Subject field(s)
- Morphology and General Physiology
- Cytology
Record 4, Main entry term, English
- chromogranin
1, record 4, English, chromogranin
correct
Record 4, Abbreviations, English
Record 4, Synonyms, English
Record 4, Textual support, English
Record 4, French
Record 4, Domaine(s)
- Morphologie et physiologie générale
- Cytologie
Record 4, Main entry term, French
- chromogranine
1, record 4, French, chromogranine
correct, feminine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
Record 4, Textual support, French
Record number: 4, Textual support number: 1 CONT
Les chromogranines sont synthétisées par les cellules chromaffines des glandes surrénales; elles sont libérées en même temps que les catécholamines (l'adrénaline et la noradrénaline). Ces chromagranines sont dégradées en peptides, et certains d'entre eux, telle la sécrétolytine, ont des propriétés antibactériennes. [...] La famille des chromogranines se compose, aujourd'hui, de six membres: les chromogranines A, B et C, et les sécrétogranines III, IV et V [...] 1, record 4, French, - chromogranine
Record number: 4, Textual support number: 1 OBS
[Les chromogranines] sont anormalement abondantes dans le sang des patients atteints de cancer du côlon et de la prostate : elles pourraient être utilisées comme marqueurs tumoraux (une augmentation de leur concentration sanguine avertirait les cliniciens de l'installation éventuelle d'un mécanisme tumoral). De surcroît, [...] certains peptides issus de la dégradation des chromogranines ont des propriétés antibactériennes. 1, record 4, French, - chromogranine
Record 4, Spanish
Record 4, Textual support, Spanish
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