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CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR [2 records]
Record 1 - internal organization data 1997-04-23
Record 1, English
Record 1, Subject field(s)
- Genetics
Record 1, Main entry term, English
- cystic fibrosis transmembrane conductance regulator
1, record 1, English, cystic%20fibrosis%20transmembrane%20conductance%20regulator
correct
Record 1, Abbreviations, English
- CFTR 2, record 1, English, CFTR
correct
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Cystic fibrosis (CF) is a common lethal genetic disease that manifests itself in airway and other epithelial cells as defective chloride ion absorption and secretion. The gene responsible for CF has been identified and predicted to encode a membrane protein termed the CF transmembrane conductance regulator (CFTR). Here we demonstrate that CFTR is a membrane-associated glycoprotein that can be phosphorylated in vitro by cAMP-dependent protein kinase. 2, record 1, English, - cystic%20fibrosis%20transmembrane%20conductance%20regulator
Record number: 1, Textual support number: 1 OBS
Tiré du périodique "Nature", 1990, 347 (6291), 382-386. 2, record 1, English, - cystic%20fibrosis%20transmembrane%20conductance%20regulator
Record 1, French
Record 1, Domaine(s)
- Génétique
Record 1, Main entry term, French
- régulateur de la perméabilité transmembranaire de la fibrose kystique 1, record 1, French, r%C3%A9gulateur%20de%20la%20perm%C3%A9abilit%C3%A9%20transmembranaire%20de%20la%20fibrose%20kystique
Record 1, Abbreviations, French
Record 1, Synonyms, French
- CFTR 2, record 1, French, CFTR
correct, masculine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 OBS
Protéine transmembranaire intervenant dans la perméabilité de la membrane plasmique au chlore (canal chlore) 1, record 1, French, - r%C3%A9gulateur%20de%20la%20perm%C3%A9abilit%C3%A9%20transmembranaire%20de%20la%20fibrose%20kystique
Record 1, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 1996-09-10
Record 2, English
Record 2, Subject field(s)
- Genetics
Record 2, Main entry term, English
- cystic fibrosis transmembrane conductance regulator gene
1, record 2, English, cystic%20fibrosis%20transmembrane%20conductance%20regulator%20gene
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
- CFTR gene 1, record 2, English, CFTR%20gene
correct
Record 2, Textual support, English
Record 2, French
Record 2, Domaine(s)
- Génétique
Record 2, Main entry term, French
- gène CFTR
1, record 2, French, g%C3%A8ne%20CFTR
correct, masculine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
Du fait de sa fréquence et de sa gravité, la muscovidose a été une des premières maladies héréditaires pour laquelle on ait envisagé la thérapie génique. Elle est caractérisée par l'inactivation de la protéine «cystic fibrosis transmembrane conductance regulator» (CFTR). 1, record 2, French, - g%C3%A8ne%20CFTR
Record 2, Spanish
Record 2, Textual support, Spanish
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