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CYSTOSARCOMA [2 records]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2018-03-29

English

Subject field(s)
  • The Genitals
CONT

Phyllodes tumor. Previously known as "cystosarcoma phyllodes", this neoplasm is a bulky, fibroma-like tumor (i,e,, made up of proliferative ducts and stroma) having on cross section numerous clefts and slits creating leaflike [phyllodes] patterns of intervening tumor. Phyllodes tumors can be very large, causing breast distortion and pressure necrosis of overlying skin. These lesions can be either malignant (uncommon) or benign (common). Changes suggesting malignant potential include increased cellularity, anaplasia, high mitotic activity, and overgrowth of the stromal component.

OBS

The term cystosarcoma phyllodes is a poor one, as both benign and malignant variants of the lesion occur, but it is well established in the medical literature.

Key term(s)
  • cystosarcoma phylloides

French

Domaine(s)
  • Organes génitaux
DEF

Variété de tumeur du sein.

CONT

Tumeur phyllode. Cette lésion, aussi appelée fibro-adénome géant ou cystadénofibrome phyllode, constitue une entité anatomoclinique qu'il faut distinguer des tumeurs bénignes fibroépithéliales. Histologiquement, l'aspect fondamental se rapproche de celui du fibro-adénome intracanaliculaire mais la prolifération épithéliale est plus active, et le stroma beaucoup plus cellulaire. Les noyaux sont actifs, parfois en mitoses, sans atypies cependant. Le tissu conjonctif peut être particulièrement lâche et myxoïde. Macroscopiquement, la tumeur apparaît, à la coupe, parsemée de feuilles arborisées (phyllodes = en forme de feuille), qui limitent des nodules plus ou moins gélatineux qui font saillie.

OBS

Appelées à tort cystosarcomes phyllodes dans la littérature anglo-saxonne, elles correspondent à des fibro-adénomes dans lesquels la composante conjonctive a pris le pas sur la composante épithéliale. Leur architecture arborescente est à l'origine de leur nom.

OBS

Selon l'importance quantitative et qualitative des cellules conjonctives, la présence de remaniements nécrotiques, œdémateux, myxoïdes, diverses classifications ont été proposées allant du simple fibro-adénome «enrichi» en fibroblastes (grade I) à l'authentique sarcome fibroblastique (grade IV).

Key term(s)
  • maladie de Brodie

Spanish

Save record 1

Record 2 2012-05-03

English

Subject field(s)
  • Cancers and Oncology
DEF

A sarcoma with cysts.

French

Domaine(s)
  • Cancers et oncologie
DEF

Sarcome renfermant des cavités kystiques.

Spanish

Save record 2

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