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CYTOTOXICITY [8 records]
Record 1 - internal organization data 2023-03-22
Record 1, English
Record 1, Subject field(s)
- Immunology
Record 1, Main entry term, English
- antibody dependent cellular cytotoxicity
1, record 1, English, antibody%20dependent%20cellular%20cytotoxicity
correct
Record 1, Abbreviations, English
- ADCC 2, record 1, English, ADCC
correct, see observation
Record 1, Synonyms, English
- antibody-dependent cell toxicity 3, record 1, English, antibody%2Ddependent%20cell%20toxicity
correct, see observation
- antibody-dependent cell-mediated cytotoxicity 1, record 1, English, antibody%2Ddependent%20cell%2Dmediated%20cytotoxicity
correct, see observation
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
A cytotoxic reaction in which Fc receptor-bearing killer cells recognize target cells via antibodies. 4, record 1, English, - antibody%20dependent%20cellular%20cytotoxicity
Record number: 1, Textual support number: 1 OBS
Related term: antibody-mediated cytotoxicity. 4, record 1, English, - antibody%20dependent%20cellular%20cytotoxicity
Record number: 1, Textual support number: 2 OBS
The term "dependent," when used as an adjective as is the case here, is more frequently written with an "e." "Dependant with an "a" represents the noun form. 5, record 1, English, - antibody%20dependent%20cellular%20cytotoxicity
Record 1, Key term(s)
- antibody dependent cell toxicity
- antibody dependent cellular cytotoxicity
- antibody dependent cell-mediated cytotoxicity
- antibody-dependant cell toxicity
Record 1, French
Record 1, Domaine(s)
- Immunologie
Record 1, Main entry term, French
- cytotoxicité cellulaire dépendant des anticorps
1, record 1, French, cytotoxicit%C3%A9%20cellulaire%20d%C3%A9pendant%20des%20anticorps
correct, feminine noun
Record 1, Abbreviations, French
- ADCC 2, record 1, French, ADCC
correct
Record 1, Synonyms, French
- cytotoxicité dépendante de la présence d'anticorps 3, record 1, French, cytotoxicit%C3%A9%20d%C3%A9pendante%20de%20la%20pr%C3%A9sence%20d%27anticorps
correct, feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Mécanisme de destruction d'une cellule (cible) par une cellule tueuse (K ou killer) dans laquelle la machinerie lytique est déclenchée par l'interaction de récepteurs membranaires, FcR, avec des anticorps fixés sur des antigènes présents sur la cellule cible. 1, record 1, French, - cytotoxicit%C3%A9%20cellulaire%20d%C3%A9pendant%20des%20anticorps
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Inmunología
Record 1, Main entry term, Spanish
- citotoxicidad celular dependiente de anticuerpos
1, record 1, Spanish, citotoxicidad%20celular%20dependiente%20de%20anticuerpos
correct, feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
- citotoxicidad mediada por células dependientes de anticuerpos 1, record 1, Spanish, citotoxicidad%20mediada%20por%20c%C3%A9lulas%20dependientes%20de%20anticuerpos
correct, feminine noun
- ADCC 1, record 1, Spanish, ADCC
correct, feminine noun
- ADCC 1, record 1, Spanish, ADCC
Record 1, Textual support, Spanish
Record 2 - internal organization data 2014-07-21
Record 2, English
Record 2, Subject field(s)
- Immunology
Record 2, Main entry term, English
- complement-dependent cytotoxicity
1, record 2, English, complement%2Ddependent%20cytotoxicity
correct
Record 2, Abbreviations, English
- CDC 2, record 2, English, CDC
correct
Record 2, Synonyms, English
- complement dependent cytotoxicity 3, record 2, English, complement%20dependent%20cytotoxicity
correct
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
The number of anti-cancer antibodies in therapy and in clinical trials is increasing gradually while their curative efficacy remains rather limited due to the resistance of tumor cells to complement-dependent cytotoxicity (CDC). 1, record 2, English, - complement%2Ddependent%20cytotoxicity
Record 2, Key term(s)
- complement-dependant cytotoxicity
Record 2, French
Record 2, Domaine(s)
- Immunologie
Record 2, Main entry term, French
- cytotoxicité dépendant du complément
1, record 2, French, cytotoxicit%C3%A9%20d%C3%A9pendant%20du%20compl%C3%A9ment
correct, feminine noun
Record 2, Abbreviations, French
- CDC 2, record 2, French, CDC
correct, feminine noun
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
Le mode exact par lequel les anticorps neutralisent et détruisent les cellules cancéreuses est encore imparfaitement compris. Il est cependant clair que trois mécanismes entrent en jeu : l'induction de la mort cellulaire (apoptose), la cytotoxicité dépendant des anticorps (CDA) et la cytotoxicité dépendant du complément (CDC), appelées collectivement les fonctions effectrices. 3, record 2, French, - cytotoxicit%C3%A9%20d%C3%A9pendant%20du%20compl%C3%A9ment
Record 2, Spanish
Record 2, Textual support, Spanish
Record 3 - internal organization data 2013-05-30
Record 3, English
Record 3, Subject field(s)
- Cytology
- Environmental Studies and Analyses
Record 3, Main entry term, English
- cytotoxicity
1, record 3, English, cytotoxicity
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 DEF
The quality of being capable of producing a specific toxic action upon cells of special organs. 2, record 3, English, - cytotoxicity
Record 3, French
Record 3, Domaine(s)
- Cytologie
- Études et analyses environnementales
Record 3, Main entry term, French
- cytotoxicité
1, record 3, French, cytotoxicit%C3%A9
correct, feminine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 DEF
Activité toxique contre certaines cellules. 2, record 3, French, - cytotoxicit%C3%A9
Record number: 3, Textual support number: 1 OBS
La cytotoxicité peut résulter de l'activité d'anticorps dirigés contre les antigènes dont la cellule est porteuse, en présence de complément. Mais la cytotoxicité peut être aussi le fait de cellules agressives, [...] si bien qu'on est amené à des formulations [...] de la cytotoxicité cellulaire [...] où le préfixe cyto désigne la cellule cible et l'adjectif cellulaire la cellule agressive; par exemple lymphocytoxicité, où lympho- concerne le lymphocyte cytotoxique, et cyto- la cellule victime de cette cytotoxité. 2, record 3, French, - cytotoxicit%C3%A9
Record 3, Spanish
Record 3, Campo(s) temático(s)
- Citología
- Estudios y análisis del medio ambiente
Record 3, Main entry term, Spanish
- citotoxicidad
1, record 3, Spanish, citotoxicidad
correct, feminine noun
Record 3, Abbreviations, Spanish
Record 3, Synonyms, Spanish
Record 3, Textual support, Spanish
Record number: 3, Textual support number: 1 DEF
Capacidad o tendencia a producir una acción tóxica sobre células específicas. 1, record 3, Spanish, - citotoxicidad
Record 4 - internal organization data 2012-01-05
Record 4, English
Record 4, Subject field(s)
- Microbiology and Parasitology
Record 4, Main entry term, English
- macrophage-mediated cytotoxicity
1, record 4, English, macrophage%2Dmediated%20cytotoxicity
correct
Record 4, Abbreviations, English
Record 4, Synonyms, English
Record 4, Textual support, English
Record number: 4, Textual support number: 1 CONT
Daily intraperitoneal injections of Aldicarb for 7 days caused a 64% suppression in macrophage-mediated cytotoxicity to LSA tumor cells in C3H mice. 1, record 4, English, - macrophage%2Dmediated%20cytotoxicity
Record number: 4, Textual support number: 2 CONT
Decreased macrophage-mediated cytotoxicity in mammary-tumor bearing mice is related to alteration of nitric-oxide production and/or release. 2, record 4, English, - macrophage%2Dmediated%20cytotoxicity
Record 4, French
Record 4, Domaine(s)
- Microbiologie et parasitologie
Record 4, Main entry term, French
- cytotoxicité à médiation macrophagique
1, record 4, French, cytotoxicit%C3%A9%20%C3%A0%20m%C3%A9diation%20macrophagique
proposal, feminine noun
Record 4, Abbreviations, French
Record 4, Synonyms, French
Record 4, Textual support, French
Record 4, Spanish
Record 4, Textual support, Spanish
Record 5 - internal organization data 2011-07-25
Record 5, English
Record 5, Subject field(s)
- Medical and Surgical Equipment
- Bioengineering
- Blood
Record 5, Main entry term, English
- cytotoxicity assay
1, record 5, English, cytotoxicity%20assay
correct
Record 5, Abbreviations, English
Record 5, Synonyms, English
Record 5, Textual support, English
Record number: 5, Textual support number: 1 OBS
Term(s) taken from a Canadian laboratory-equipment company's catalogue. 1, record 5, English, - cytotoxicity%20assay
Record 5, French
Record 5, Domaine(s)
- Équipement médico-chirurgical
- Technique biologique
- Sang
Record 5, Main entry term, French
- épreuve de cytotoxicité
1, record 5, French, %C3%A9preuve%20de%20cytotoxicit%C3%A9
feminine noun
Record 5, Abbreviations, French
Record 5, Synonyms, French
Record 5, Textual support, French
Record number: 5, Textual support number: 1 OBS
Terme(s) tiré(s) du catalogue d'une compagnie canadienne d'équipement de laboratoire. 1, record 5, French, - %C3%A9preuve%20de%20cytotoxicit%C3%A9
Record 5, Spanish
Record 5, Textual support, Spanish
Record 6 - internal organization data 2011-07-19
Record 6, English
Record 6, Subject field(s)
- Medical and Surgical Equipment
- Bioengineering
- Blood
Record 6, Main entry term, English
- Clostridium difficile cytotoxicity assay
1, record 6, English, Clostridium%20difficile%20cytotoxicity%20assay
correct
Record 6, Abbreviations, English
Record 6, Synonyms, English
Record 6, Textual support, English
Record number: 6, Textual support number: 1 OBS
Term(s) taken from a Canadian laboratory-equipment company's catalogue. 1, record 6, English, - Clostridium%20difficile%20cytotoxicity%20assay
Record 6, French
Record 6, Domaine(s)
- Équipement médico-chirurgical
- Technique biologique
- Sang
Record 6, Main entry term, French
- épreuve de cytotoxicité pour Clostridium difficile
1, record 6, French, %C3%A9preuve%20de%20cytotoxicit%C3%A9%20pour%20Clostridium%20difficile
feminine noun
Record 6, Abbreviations, French
Record 6, Synonyms, French
Record 6, Textual support, French
Record number: 6, Textual support number: 1 OBS
Terme(s) tiré(s) du catalogue d'une compagnie canadienne d'équipement de laboratoire. 1, record 6, French, - %C3%A9preuve%20de%20cytotoxicit%C3%A9%20pour%20Clostridium%20difficile
Record 6, Spanish
Record 6, Textual support, Spanish
Record 7 - internal organization data 2006-05-08
Record 7, English
Record 7, Subject field(s)
- Environmental Studies and Analyses
- Cytology
Record 7, Main entry term, English
- cytotoxicity test 1, record 7, English, cytotoxicity%20test
Record 7, Abbreviations, English
Record 7, Synonyms, English
Record 7, Textual support, English
Record number: 7, Textual support number: 1 OBS
cytotoxicity: the quality of being capable of producing a specific toxic action upon cells of special organs. 2, record 7, English, - cytotoxicity%20test
Record 7, French
Record 7, Domaine(s)
- Études et analyses environnementales
- Cytologie
Record 7, Main entry term, French
- test de cytotoxicité
1, record 7, French, test%20de%20cytotoxicit%C3%A9
correct, masculine noun
Record 7, Abbreviations, French
Record 7, Synonyms, French
Record 7, Textual support, French
Record number: 7, Textual support number: 1 CONT
La notion d'action cytotoxique d'un polluant [...] exprime l'action métabolique sur les cellules de l'appareil respiratoire. Cette notion de cytotoxicité oppose certaines poussières comme la silice à d'autres comme le charbon [...]. Le meilleur test de cytotoxicité est représenté par la mort de la cellule, et peut-être, à un stade prélétal, par la libération d'enzymes cytoplasmiques dans le milieu extérieur ou par la pénétration de colorants vitaux à l'intérieur de la cellule indiquant une perméabilité anormale de la membrane plasmique. 1, record 7, French, - test%20de%20cytotoxicit%C3%A9
Record 7, Spanish
Record 7, Campo(s) temático(s)
- Estudios y análisis del medio ambiente
- Citología
Record 7, Main entry term, Spanish
- ensayo de citotoxicidad
1, record 7, Spanish, ensayo%20de%20citotoxicidad
correct, masculine noun
Record 7, Abbreviations, Spanish
Record 7, Synonyms, Spanish
- prueba de citotoxicidad 1, record 7, Spanish, prueba%20de%20citotoxicidad
correct, feminine noun
Record 7, Textual support, Spanish
Record 8 - internal organization data 1993-03-05
Record 8, English
Record 8, Subject field(s)
- Immunology
Record 8, Main entry term, English
- cell-mediated lympholysis 1, record 8, English, cell%2Dmediated%20lympholysis
Record 8, Abbreviations, English
Record 8, Synonyms, English
- lymphocyte-mediated cytotoxicity 2, record 8, English, lymphocyte%2Dmediated%20cytotoxicity
- CTL-mediated lysis 2, record 8, English, CTL%2Dmediated%20lysis
Record 8, Textual support, English
Record number: 8, Textual support number: 1 DEF
A variation of the mixed lymphocyte culture (MLC) techniques that is a functional test of the ability of cytotoxic lymphocytes (CTL) to kill target cells. Lymphocytes from two individuals are cultured together for several days, one population having been prevented from proliferating by treatment with radiation or mitomycin (a "one-way" MLC); they are then cultured for several hours with 51CR-labeled target cells that are HLA-identical to the stimulator cells. Cytotoxicity is measured as percentage of 51CR released from specific target cells compared to percentage of 51CR released from control (nonspecific target) cells. 1, record 8, English, - cell%2Dmediated%20lympholysis
Record 8, French
Record 8, Domaine(s)
- Immunologie
Record 8, Main entry term, French
- cytotoxicité à médiation lymphocytaire
1, record 8, French, cytotoxicit%C3%A9%20%C3%A0%20m%C3%A9diation%20lymphocytaire
feminine noun
Record 8, Abbreviations, French
Record 8, Synonyms, French
- lymphocytotoxicité à médiation cellulaire 2, record 8, French, lymphocytotoxicit%C3%A9%20%C3%A0%20m%C3%A9diation%20cellulaire
feminine noun
- lympholyse à médiation cellulaire 3, record 8, French, lympholyse%20%C3%A0%20m%C3%A9diation%20cellulaire
feminine noun
Record 8, Textual support, French
Record number: 8, Textual support number: 1 CONT
Test de cytotoxicité à médiation lymphocytaire. Lorsque des lymphocytes provenant de deux populations allogéniques différentes sont mis en présence dans un tube, on assiste à l'apparition de lymphoblastes (ce qui définit la réaction lymphocytaire mixte), mais aussi à celle d'une génération de cellules T cytotoxiques spécifiques. C'est la réaction de lymphocytotoxicité à médiation cellulaire appelée en anglais "cell mediated lympholysis". 1, record 8, French, - cytotoxicit%C3%A9%20%C3%A0%20m%C3%A9diation%20lymphocytaire
Record 8, Spanish
Record 8, Textual support, Spanish
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