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DIRTY DRUG [3 records]

Record 1 2024-11-27

English

Subject field(s)
  • Drugs and Drug Addiction
CONT

Syringe access programs operate with the primary goal of providing injection drug users with new, sterile injection equipment as a means of reducing the spread of blood-borne viruses and other injection-related infections. In addition, there has traditionally been an emphasis placed on simultaneously removing used injection equipment from circulation through a process of exchanging old syringes for new ones.

Key term(s)
  • used drug injecting paraphernalia
  • used drug injecting equipment
  • used injecting paraphernalia
  • used injecting equipment
  • dirty drug injecting paraphernalia
  • dirty drug injecting equipment
  • dirty injecting paraphernalia
  • dirty injecting equipment

French

Domaine(s)
  • Drogues et toxicomanie
CONT

[...] certaines situations qui surviennent dans la trajectoire de consommation peuvent provoquer l'utilisation de matériel d'injection usagé.

OBS

Le matériel d'injection comprend les seringues et les aiguilles, ainsi que les filtres, de l'eau stérile et les contenants pour dissoudre et chauffer la drogue.

Spanish

Save record 1

Record 2 2024-04-19

English

Subject field(s)
  • Drugs and Drug Addiction
CONT

Understanding a positive drug test result. A positive result on a drug test simply means that the person had a detectable amount of a substance present during a certain window of time. A positive result doesn't necessarily mean that the person is currently intoxicated or experiencing the effects of the substance. A positive result also doesn't necessarily mean that the person has a substance use disorder.

Key term(s)
  • positive result to a drug test

French

Domaine(s)
  • Drogues et toxicomanie

Spanish

Save record 2

Record 3 2011-12-14

English

Subject field(s)
  • Medication
CONT

Sutent (SU11248) is a relatively "dirty" drug (in that it hits multiple targets) and has some affinity for 74 different kinases. PTK787 was one of the "cleanest" drugs tested in this study ... Being a "dirty" drug is not necessarily a bad thing. … The trick is that most cancers have more than one target. They might have five or six targets and you have to knock out three to stop the cancer ...

CONT

The rationale for multi-target drugs has been strengthened both on theoretical and empirical grounds. Serious diseases that are intractable to treatment were found to have multiple pathogenic factors and examples of successful drugs were shown to affect multiple disease targets. The salient features of multiple-target drugs, low target affinity and rapid binding kinetics, have been responsible for their late discovery and slow development.

French

Domaine(s)
  • Médicaments
CONT

La première activité décrite du sorafénib était celle d'inhibiteur de sérine/thréonine kinase de la protéine Raf-1. Par la suite, les autres cibles ont été successivement identifiées. En bloquant plusieurs voies de transduction différentes, ces médicaments multicibles présentent donc l'intérêt d'avoir une action prédominante sur l'angiogenèse mais aussi sur la prolifération cellulaire et l'apoptose.

Spanish

Save record 3

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