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NUCLEOTIDE BINDING FOLD [1 record]

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Record 1 1991-07-18

English

Subject field(s)
  • Biochemistry
CONT

A cluster of cystic fibrosis mutations in the first nucleotide-binding fold of the cystic fibrosis conductance regulator protein.

OBS

Tiré du périodique "nature", London, 1990, 346 (6282), pp. 366-369.

French

Domaine(s)
  • Biochimie
CONT

L'analyse génétique a attiré l'attention sur l'une des deux régions potentielles de liaison de l'ATP située à proximité de l'extrémité N-terminale du CFTR (NBF1, nucleotide binding fold). En effet, celle-ci renferme en position 508 un résidu de phénylalanine dont la délétion est retrouvée chez 68% des patients ou des transmetteurs.

Spanish

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