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PBPK MODEL [1 record]
Record 1 - internal organization data 2026-03-03
Record 1, English
Record 1, Subject field(s)
- Pharmacology
- Toxicology
- Collaboration with Health Canada
Record 1, Main entry term, English
- physiologically based pharmacokinetic model
1, record 1, English, physiologically%20based%20pharmacokinetic%20model
correct, noun
Record 1, Abbreviations, English
Record 1, Synonyms, English
- physiologically-based pharmacokinetic model 2, record 1, English, physiologically%2Dbased%20pharmacokinetic%20model
correct, noun
- PBPK model 2, record 1, English, PBPK%20model
correct, noun
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
A physiologically-based pharmacokinetic (PBPK) model represents the structural components of the body with physiologically relevant compartments connected via blood flow rates described by mathematical equations to determine drug disposition. PBPK models are used in the pharmaceutical sector for drug development, precision medicine, and the chemical industry to predict safe levels of exposure during the registration of chemical substances. 2, record 1, English, - physiologically%20based%20pharmacokinetic%20model
Record 1, French
Record 1, Domaine(s)
- Pharmacologie
- Toxicologie
- Collaboration avec Santé Canada
Record 1, Main entry term, French
- modèle pharmacocinétique fondé sur la physiologie
1, record 1, French, mod%C3%A8le%20pharmacocin%C3%A9tique%20fond%C3%A9%20sur%20la%20physiologie
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- modèle pharmacocinétique basé sur la physiologie 2, record 1, French, mod%C3%A8le%20pharmacocin%C3%A9tique%20bas%C3%A9%20sur%20la%20physiologie
correct, masculine noun
- modèle pharmacocinétique physiologique 3, record 1, French, mod%C3%A8le%20pharmacocin%C3%A9tique%20physiologique
correct, masculine noun
- modèle PBPK 4, record 1, French, mod%C3%A8le%20PBPK
correct, masculine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Un modèle pharmacocinétique physiologique (PBPK) est un modèle mathématique construit pour prédire l'absorption, la distribution, le métabolisme et l'excrétion (ADME) de substances chimiques naturelles ou synthétiques chez l'homme ou l'animal. Ce type de modèle est utilisé dans la recherche et le développement de nouveaux médicaments, pour l'évaluation des risques de toxicité des substances chimiques et en biologie. 3, record 1, French, - mod%C3%A8le%20pharmacocin%C3%A9tique%20fond%C3%A9%20sur%20la%20physiologie
Record 1, Spanish
Record 1, Textual support, Spanish
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