Dr. Robson's laboratory is studying some of the important house-keeping genes of P. falciparum which cause severe malaria in man. Her team has recently isolated and sequenced the parasite's calmodulin gene; discovered a new gene encoding a protein called thrombospondin-related anonymous protein which has many sequence motifs of particular interest, particularly those homologous to human properdin and thrombospondin; and has defined a family of ATPase-like genes in P. falciparum. 3, record 1, English, - thrombospondin%20related%20anonymous%20protein
[...] les LTC (lymphocytes T cytotoxiques) pourraient intervenir dans la résistance au paludisme en détruisant les cellules infectées avant que les manifestations cliniques apparaissent. Pour tester cette hypothèse, les chercheurs ont synthétisé 70 peptides longs de 8 à 10 acides aminés et correspondant à des fragments de quatre antigènes plasmodiaux: LSA-1 (liver stage antigen 1), TRAP (thrombospondin related anonymous protein) et STARP (sporozoite threonine and asparagine rich protein). 1, record 1, French, - TRAP
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