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THYMUS-DEPENDENT [3 records]

Record 1 2023-03-22

English

Subject field(s)
  • Immunology
DEF

An antigen which requires an immune response from thymus-derived lymphocytes (T lymphocytes) in order to elicit an immune response in B lymphocytes which then mature into antibody-forming cells.

DEF

One that requires the presence of helper T cells to stimulate antibody production by B cells; most antigens are T-dependent.

CONT

T-dependent antigens require immune recognition by both T and B cells to produce an immune response.

OBS

The term "dependent," when used as an adjective as is the case here, is more frequently written with an "e." "Dependant with an "a" represents the noun form.

Key term(s)
  • thymus-dependant antigen
  • T-dependant antigen

French

Domaine(s)
  • Immunologie
DEF

Antigène vis-à-vis duquel la production des anticorps (des IgG et à un moindre degré des IgM) nécessite l'intervention des cellules T.

CONT

Antigènes thymodépendants : protéines sériques xénogéniques, polypeptides synthétiques de L-acides aminés, hématies xénogéniques, flagelline monomérique. (J.-F. Bach, P. Lesavre. Op. cit., p.43).

CONT

Les antigènes T-dépendants doivent être reconnus à la fois par les cellules T et B pour qu'il se produise une réponse immunitaire.

Spanish

Campo(s) temático(s)
  • Inmunología
Save record 1

Record 2 1993-01-08

English

Subject field(s)
  • Immunology
DEF

Those portions of the peripheral lymphoid organs which are characterized by a population of thymus-dependent lymphocytes (T lymphocytes), as the paracortical areas of lymph nodes, internodular zone of Peyer's patches, and the centers of the malpighian corpuscule of the spleen.

French

Domaine(s)
  • Immunologie
DEF

Région des organes lymphoïde périphériques où migrent sélectivement les cellules T.

CONT

L'étude morphologique comparée du système lymphoide des animaux normaux et thymoprives et l'analyse des modifications morphologiques respectivement associées aux réactions d'immunité cellulaire et humorale ont permis d'individualiser des zones thymodépendantes (aire paracorticale des ganglions, manchon lymphoïde périartériel de la pulpe blanche de la rate) et des zones thymo-indépendantes [...].

Spanish

Save record 2

Record 3 1979-04-30

English

Subject field(s)
  • Immunology
CONT

Our data show that mice with a genetic absence of the thymus and thymus-dependent immune functions do not show an inordinate incidence of spontaneous or chemically induced malignancies. This is true even when the athymic animals are kept under conditions that permit their observation during useful periods of time ...

French

Domaine(s)
  • Immunologie
DEF

Dépendant du thymus ou des cellules T.

CONT

Il a été montré dernièrement que l'injection d'EBP à des souris augmente leur résistance à des infections bactériennes. (...) Afin de rechercher si cette immunostimulation nécessite l'intervention de lymphocytes thymodépendants, nous avons utilisé des souris thymoprives TP et non thymoprives NTP provenant de la même fratrie.

Spanish

Save record 3

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