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TYPE I HYPERSENSITIVITY REACTION [2 records]

Record 1 2010-03-24

English

Subject field(s)
  • Immunology
DEF

(Gell and Coombs classification) : Type I reactions are initiated by antigens reacting with cell-bound antibody, usually IgE. Release of mediators, mainly from basophils and mast cells, provide the pathogenic mechanism.

French

Domaine(s)
  • Immunologie
DEF

Réaction d'immunité humorale. La combinaison antigène-anticorps provoque la libération par les cellules basophiles ou les mastocytes d'histamine et de substances vaso-actives. Les anticorps sont des IgE. La réaction est précoce. En clinique, l'asthme franc, la pollinose, le choc anaphylactique, certaines urticaires sont dues à la réaction de type I.

Spanish

Campo(s) temático(s)
  • Inmunología
Save record 1

Record 2 1993-03-22

English

Subject field(s)
  • Immunology
DEF

A rapidly occurring (within 30 min) antibody-mediated reaction arising from the release of histamine and other vasoactive substances. The antibody (an immunoglobulin, usually of IgE type) fixes to cells, especially mast cells. On contact with antigen, the cell is disrupted and vasoactive substances are released and produce anaphylaxis.

French

Domaine(s)
  • Immunologie
CONT

Classification des réactions allergiques selon le délai d'apparition [...] deux catégories : 1) les réactions d'hypersensibilité de type immédiat qui surviennent très rapidement après le contact avec l'allergène. L'anaphylaxie cutanée survient en quelques minutes. La réaction d'Arthus, [...] atteint son maximum en 3 à 6 heures après le contact avec l'allergène [...]; 2) les réactions d'hypersensibilité du type retardé [...]

Spanish

Save record 2

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