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UNCOMPETITIVE ENZYME INHIBITION [1 record]
Record 1 - internal organization data 2011-01-11
Record 1, English
Record 1, Subject field(s)
- Biological Sciences
Record 1, Main entry term, English
- uncompetitive enzyme inhibition
1, record 1, English, uncompetitive%20enzyme%20inhibition
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- uncompetitive inhibition 2, record 1, English, uncompetitive%20inhibition
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
The prevention of an enzymic process as a result of the interaction of an inhibitor with the enzyme-substrate complex or a subsequent intermediate form of the enzyme, but not with the free enzyme. 1, record 1, English, - uncompetitive%20enzyme%20inhibition
Record number: 1, Textual support number: 1 CONT
In uncompetitive inhibition which is not very aptly named, the inhibitor does not combine with the free enzyme or affect its reaction with its normal substrate; however, it does combine with the enzyme-substrate complex to give an inactive enzyme-substrate-inhibitor complex, which cannot undergo further reaction to yield the normal product ... Uncompetitive inhibition is rare in one-substrate reactions. 3, record 1, English, - uncompetitive%20enzyme%20inhibition
Record 1, French
Record 1, Domaine(s)
- Sciences biologiques
Record 1, Main entry term, French
- inhibition incompétitive
1, record 1, French, inhibition%20incomp%C3%A9titive
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- inhibition par blocage du complexe intermédiaire 2, record 1, French, inhibition%20par%20blocage%20du%20complexe%20interm%C3%A9diaire
correct, feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Inhibition par blocage du complexe ES enzyme-substrat. On suppose l'existence sur l'enzyme de deux sites de fixation, l'un réservé au substrat, l'autre à l'inhibiteur, mais ce dernier ne peut se fixer de façon réversible que sur le complexe intermédiaire ES. [...] L'inhibiteur ne permet pas au complexe ternaire ESI, d'évoluer vers l'élaboration du produit. 1, record 1, French, - inhibition%20incomp%C3%A9titive
Record number: 1, Textual support number: 1 CONT
Dans l'inhibition incompétitive, le degré d'inhibition peut s'élever lorsque la concentration en substrat est augmentée, contrairement à l'inhibition non compétitive, où l'inhibiteur n'est pas déplacé lorsqu'on augmente la concentration en substrat. L'inhibition incompétitive est rare dans les réactions à un substrat mais banale dans les réactions à deux substrats. 2, record 1, French, - inhibition%20incomp%C3%A9titive
Record number: 1, Textual support number: 1 OBS
Voir «inhibition compétitive», «inhibition non compétitive». 2, record 1, French, - inhibition%20incomp%C3%A9titive
Record 1, Spanish
Record 1, Textual support, Spanish
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