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WISKOTT-ALDRICH SYNDROME [2 records]
Record 1 - internal organization data 2006-05-08
Record 1, English
Record 1, Subject field(s)
- Immunology
Record 1, Main entry term, English
- Wiskott-Aldrich syndrome
1, record 1, English, Wiskott%2DAldrich%20syndrome
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- Aldrich syndrome 2, record 1, English, Aldrich%20syndrome
correct
- immunodeficiency with thrombocytopenia and eczema 1, record 1, English, immunodeficiency%20with%20thrombocytopenia%20and%20eczema
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
[An] X-linked recessive syndrome is characterized clinically by the triad of eczema, thrombocytopenic purpura, and undue susceptibility to infection. 3, record 1, English, - Wiskott%2DAldrich%20syndrome
Record number: 1, Textual support number: 1 OBS
Often there is prolonged oozing from the circumcision site or bloody diarrhea during infancy. Atopic dermatitis and recurrent infections usually develop during the first year of life. Infections are caused by pneumococci and other bacteria with polysaccharide capsules, resulting in episodes of otitis media, pneumonia, meningitis, and sepsis. Later, infections with Pneumocystis carinii and the herpesviruses become more frequent. 3, record 1, English, - Wiskott%2DAldrich%20syndrome
Record 1, French
Record 1, Domaine(s)
- Immunologie
Record 1, Main entry term, French
- syndrome de Wiskott-Aldrich
1, record 1, French, syndrome%20de%20Wiskott%2DAldrich
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- eczéma-thrombocytopénie-immunodéficience 1, record 1, French, ecz%C3%A9ma%2Dthrombocytop%C3%A9nie%2Dimmunod%C3%A9ficience
correct, masculine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Déficit immunitaire, héréditaire, de transmission récessive liée au chromosome X [...] caractérisé par l'association d'une thrombopénie, d'un eczéma, d'infections à répétition et éventuellement de manifestations auto-immunes et de lymphomes. 1, record 1, French, - syndrome%20de%20Wiskott%2DAldrich
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Inmunología
Record 1, Main entry term, Spanish
- síndrome de Wiskott-Aldrich
1, record 1, Spanish, s%C3%ADndrome%20de%20Wiskott%2DAldrich
correct, masculine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record 2 - internal organization data 1996-10-17
Record 2, English
Record 2, Subject field(s)
- Biochemistry
Record 2, Main entry term, English
- Wiskott-Aldrich syndrome protein
1, record 2, English, Wiskott%2DAldrich%20syndrome%20protein
correct
Record 2, Abbreviations, English
- WASP 2, record 2, English, WASP
correct
Record 2, Synonyms, English
- WAS protein 3, record 2, English, WAS%20protein
correct
Record 2, Textual support, English
Record number: 2, Textual support number: 1 CONT
Egr-1 expression WAS protein kinase C (PKC)-dependent because staurosporine and calphostin C abrogated the urea effect, and down-regulation of PKC through chronic TPA treatment inhibited both urea-inducible Egr-1 protein expression and gene transcription. 4, record 2, English, - Wiskott%2DAldrich%20syndrome%20protein
Record number: 2, Textual support number: 1 OBS
The Journal of Clinical Investigation. April 15, 1996, Volume 97, Number 8 - abstracts. Categories. Molecular Medicine / Genetic Disorders. Infection /... 5, record 2, English, - Wiskott%2DAldrich%20syndrome%20protein
Record 2, French
Record 2, Domaine(s)
- Biochimie
Record 2, Main entry term, French
- protéine WAS
1, record 2, French, prot%C3%A9ine%20WAS
correct, feminine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
Par une analyse moléculaire approfondie, l'équipe de Uta Francke du Howard Hughes Medical Institute a cloné un gène directement impliqué [dans le syndrome de Wiskott-Aldrich (WAS) codant la protéine WASP (WAS protein). Des mutations ponctuelles sont observées chez trois familles atteintes de ce syndrome. 1, record 2, French, - prot%C3%A9ine%20WAS
Record 2, Spanish
Record 2, Textual support, Spanish
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