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CETOACIDOSIS [3 records]

Record 1 2011-09-09

English

Subject field(s)
  • Human Diseases - Various
  • Endocrine System and Metabolism
DEF

The diminished ability of cells to respond to the action of insulin in transporting glucose (sugar) from the bloodstream into muscle and other tissues.

CONT

Insulin resistance typically develops with obesity and heralds the onset of type 2 diabetes. It is as if insulin is "knocking" on the door of muscle. The muscle hears the knock, opens up, and lets glucose in. But with insulin resistance, the muscle cannot hear the knocking of the insulin (the muscle is "resistant"). The pancreas makes more insulin, which increases insulin levels in the blood and causes a louder "knock." Eventually, the pancreas produces far more insulin than normal and the muscles continue to be resistant to the knock. As long as one can produce enough insulin to overcome this resistance, blood glucose levels remain normal. Once the pancreas is no longer able to keep up, blood glucose starts to rise, initially after meals, eventually even in the fasting state. Type 2 diabetes is now overt.

Key term(s)
  • insulin-resistance

French

Domaine(s)
  • Maladies humaines diverses
  • Systèmes endocrinien et métabolique
DEF

[...] diminution de la réponse biologique à l'action de l'insuline.

CONT

L'insulinorésistance se définit comme un état de diminution de la réponse cellulaire et tissulaire à l'insuline. Associée à la diminution de la capacité sécrétoire de l'insuline, elle conduit au développement du diabète de type 2.

CONT

L'insulinorésistance est liée à un risque métabolique et cardiovasculaire accru dans le contexte du «syndrome d'insulinorésistance» (ou «syndrome plurimétabolique») [...]

Key term(s)
  • insulino-résistance

Spanish

Campo(s) temático(s)
  • Enfermedades humanas varias
  • Sistemas endocrino y metabólico
DEF

Disminución de la efectividad de la insulina para reducir los niveles de azúcar en la sangre.

OBS

Se define arbitrariamente por el requerimiento de 200 unidades o más de insulina por día para evitar la hiperglucemia o la cetosis; usualmente se debe a la fijación de la insulina a anticuerpos pero también se producen anormalidades de los receptores para insulina situados en la superficie celular; está asociada con obesidad, cetoacidosis, infección y ciertas afecciones poco frecuentes.

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Record 2 2011-08-19

English

Subject field(s)
  • Human Diseases - Various
  • The Pancreas
DEF

A chronic condition in which the pancreas makes little or no insulin because the beta cells have been destroyed and in which the body is then not able to use the glucose (blood sugar) for energy.

CONT

IDDM [insulin-dependent diabetes mellitus] usually comes on abruptly, although the damage to the beta cells may begin much earlier. The signs of IDDM are a great thirst, hunger, a need to urinate often, and loss of weight. To treat the disease, the person must inject insulin, follow a diet plan, exercise daily, and test blood glucose several times a day. IDDM usually occurs in children and adults who are under age 30.

OBS

Diabetes mellitus can be divided into two types: (1) type I, or insulin-dependent diabetes mellitus; (2) type II, or non-insulin-dependent diabetes mellitus ...

French

Domaine(s)
  • Maladies humaines diverses
  • Pancréas
CONT

On distingue classiquement deux types de diabète : le diabète insulino-dépendant (DID) (type 1) également appelé diabète maigre ou diabète de l'enfant [...]. Il résulte d'une incapacité du pancréas à sécréter une quantité suffisante d'insuline. Il s'agit d'une maladie auto-immune. Le diabète non insulino dépendant (DNID) (type 2), autrefois baptisé diabète gras, survient souvent après la quarantaine chez des personnes en surpoids.

Spanish

Campo(s) temático(s)
  • Enfermedades humanas varias
  • Páncreas
DEF

Subtipo de diabetes mellitus caracterizado por deficiencia de insulina.

CONT

La diabetes mellitus tipo 1 (DM1) se caracteriza por [la] destrucción de las células beta pancreáticas, que se traduce en un déficit absoluto de insulina y dependencia vital a la insulina exógena.

CONT

La diabetes tipo 1 se presenta cuando el cuerpo elabora poca insulina o no produce ninguna. Por esta razón, las personas con diabetes tipo 1 deben recibir inyecciones de insulina para vivir. Esta es la razón por la que a este tipo de diabetes se le denomina también "diabetes insulinodependiente".

OBS

Se manifiesta por el inicio repentino de hiperglucemia severa, progresión rápida hacia cetoacidosis diabética y la muerte a menos que sea tratada con insulina.

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Record 3 2003-06-12

English

Subject field(s)
  • Symptoms (Medicine)
DEF

A condition characterized by an abnormally elevated concentration of ketone bodies in the body tissues and fluids; it occurs when fatty acids are incompletely metabolized, a complication of diabetes mellitus, starvation, and alcoholism.

French

Domaine(s)
  • Symptômes (Médecine)
DEF

Trouble du métabolisme caractérisé par l'accumulation dans l'organisme de corps cétoniques.

Spanish

Campo(s) temático(s)
  • Síntomas (Medicina)
DEF

Presencia de cuerpos cetónicos en los tejidos y líquidos orgánicos. Síntomas de la cetosis son náuseas, vómitos y dolor de estómago. La cetosis puede conducir a la cetoacidosis.

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