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DOSIS MAXIMA TOLERADA [3 records]
Record 1 - internal organization data 2019-02-15
Record 1, English
Record 1, Subject field(s)
- Pharmacology
Record 1, Main entry term, English
- drug tolerance
1, record 1, English, drug%20tolerance
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- medication tolerance 2, record 1, English, medication%20tolerance
correct
- tolerance 3, record 1, English, tolerance
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
An adaptive state characterized by diminished responses to the same quantity of a drug. 4, record 1, English, - drug%20tolerance
Record 1, Key term(s)
- tolerance to a drug
- tolerance to a medication
Record 1, French
Record 1, Domaine(s)
- Pharmacologie
Record 1, Main entry term, French
- tolérance au médicament
1, record 1, French, tol%C3%A9rance%20au%20m%C3%A9dicament
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- tolérance 2, record 1, French, tol%C3%A9rance
correct, feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
La tolérance au médicament est le besoin de prendre de plus fortes doses du médicament pour obtenir le même effet. Par exemple, avec le temps, une personne peut avoir besoin de plus fortes doses de morphine pour soulager la même douleur. Ce n'est pas la même chose que l'accoutumance. 3, record 1, French, - tol%C3%A9rance%20au%20m%C3%A9dicament
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Farmacología
Record 1, Main entry term, Spanish
- tolerancia a medicamentos
1, record 1, Spanish, tolerancia%20a%20medicamentos
correct, feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
- tolerancia a fármacos 2, record 1, Spanish, tolerancia%20a%20f%C3%A1rmacos
correct, feminine noun
- tolerancia medicamentosa 1, record 1, Spanish, tolerancia%20medicamentosa
correct, feminine noun
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
Proceso de adaptación celular a una determinada sustancia farmacológica, de forma que son necesarias dosis cada vez mayores para producir los mismos efectos fisiológicos o psicológicos que se obtenían antes con dosis menores. 3, record 1, Spanish, - tolerancia%20a%20medicamentos
Record number: 1, Textual support number: 1 CONT
La tolerancia a medicamentos [es la] disminución progresiva de la sensibilidad de los seres humanos o los animales a los efectos de un fármaco, debido a su administración continuada. 1, record 1, Spanish, - tolerancia%20a%20medicamentos
Record number: 1, Textual support number: 1 OBS
Se debe diferenciar de fármacorresistencia, en la que el organismo, la enfermedad o un tejido no responden en la adecuada medida a la sustancia química o al fármaco. Debe diferenciarse también de la dosis máxima tolerada y del nivel sin efectos adversos observados. 1, record 1, Spanish, - tolerancia%20a%20medicamentos
Record 2 - internal organization data 2012-07-24
Record 2, English
Record 2, Subject field(s)
- Pharmacodynamics
Record 2, Main entry term, English
- therapeutic index
1, record 2, English, therapeutic%20index
correct
Record 2, Abbreviations, English
- T.I. 2, record 2, English, T%2EI%2E
correct
- TI 3, record 2, English, TI
correct
Record 2, Synonyms, English
- therapeutic ratio 4, record 2, English, therapeutic%20ratio
correct
Record 2, Textual support, English
Record number: 2, Textual support number: 1 DEF
The ratio of the LD 50 [lethal dose 50] to the ED 50 [effective dose 50]. 5, record 2, English, - therapeutic%20index
Record 2, French
Record 2, Domaine(s)
- Pharmacodynamie
Record 2, Main entry term, French
- index thérapeutique
1, record 2, French, index%20th%C3%A9rapeutique
correct, masculine noun
Record 2, Abbreviations, French
- IT 1, record 2, French, IT
correct, masculine noun
Record 2, Synonyms, French
- coefficient thérapeutique 2, record 2, French, coefficient%20th%C3%A9rapeutique
correct, masculine noun
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
[...] l'index thérapeutique [...] s'exprime par: IT = DL 50/DE 50 [dose létale 50/dose efficace 50]. 3, record 2, French, - index%20th%C3%A9rapeutique
Record 2, Key term(s)
- indice thérapeutique
- indice C/T
Record 2, Spanish
Record 2, Campo(s) temático(s)
- Farmacodinámica
Record 2, Main entry term, Spanish
- índice terapéutico
1, record 2, Spanish, %C3%ADndice%20terap%C3%A9utico
correct, masculine noun
Record 2, Abbreviations, Spanish
Record 2, Synonyms, Spanish
Record 2, Textual support, Spanish
Record number: 2, Textual support number: 1 DEF
Relación de la dosis máxima tolerada de un medicamento a la dosis mínima efectiva. 1, record 2, Spanish, - %C3%ADndice%20terap%C3%A9utico
Record 3 - internal organization data 2011-06-13
Record 3, English
Record 3, Subject field(s)
- Pharmacology
- Toxicology
Record 3, Main entry term, English
- therapeutic range
1, record 3, English, therapeutic%20range
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
Record 3, Textual support, English
Record number: 3, Textual support number: 1 CONT
Blood concentrations of drugs are usually within therapeutic range. 1, record 3, English, - therapeutic%20range
Record 3, French
Record 3, Domaine(s)
- Pharmacologie
- Toxicologie
Record 3, Main entry term, French
- marge thérapeutique
1, record 3, French, marge%20th%C3%A9rapeutique
correct, feminine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
Record 3, Textual support, French
Record number: 3, Textual support number: 1 DEF
Différence entre le taux toxique et le taux thérapeutique. 1, record 3, French, - marge%20th%C3%A9rapeutique
Record 3, Spanish
Record 3, Campo(s) temático(s)
- Farmacología
- Toxicología
Record 3, Main entry term, Spanish
- margen terapéutico
1, record 3, Spanish, margen%20terap%C3%A9utico
correct, masculine noun
Record 3, Abbreviations, Spanish
Record 3, Synonyms, Spanish
Record 3, Textual support, Spanish
Record number: 3, Textual support number: 1 DEF
Relación entre la máxima dosis tolerada, o también tóxica, y la dosis terapéutica(dosis tóxica/dosis terapéutica). 2, record 3, Spanish, - margen%20terap%C3%A9utico
Record number: 3, Textual support number: 1 OBS
En farmacología clínica se emplea como equivalente de Índice. 2, record 3, Spanish, - margen%20terap%C3%A9utico
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