TERMIUM Plus®
The Government of Canada’s terminology and linguistic data bank.
DISULFIRAM [3 records]
Record 1 - internal organization data 2011-03-28
Record 1, English
Record 1, Subject field(s)
- Biochemistry
Record 1, Main entry term, English
- aldehyde dehydrogenase
1, record 1, English, aldehyde%20dehydrogenase
correct
Record 1, Abbreviations, English
- ALDH 2, record 1, English, ALDH
correct
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Aldehyde dehydrogenases are a group of enzymes that catalyse the oxidation (dehydrogenation) of aldehydes. Multiple forms exist in mammals in the cytosol, mitochondria and endoplasmic reticulum. They have been classified as Class 1 (cytosolic), Class 2 (mitochondrial) and Class 3 (tumour and other isozymes). 3, record 1, English, - aldehyde%20dehydrogenase
Record number: 1, Textual support number: 2 CONT
[Aldehyde dehydrogenases are] isoenzymes important in cell defence against both exogenous and endogenous aldehydes. 4, record 1, English, - aldehyde%20dehydrogenase
Record number: 1, Textual support number: 1 PHR
Fatty, liver mitochondrial, long-chain, mammalian aldehyde dehydrogenase. 5, record 1, English, - aldehyde%20dehydrogenase
Record 1, French
Record 1, Domaine(s)
- Biochimie
Record 1, Main entry term, French
- aldéhyde déshydrogénase
1, record 1, French, ald%C3%A9hyde%20d%C3%A9shydrog%C3%A9nase
correct, masculine noun
Record 1, Abbreviations, French
- ALDH 2, record 1, French, ALDH
correct, masculine noun
Record 1, Synonyms, French
- aldéhyde-déshydrogénase 3, record 1, French, ald%C3%A9hyde%2Dd%C3%A9shydrog%C3%A9nase
correct, masculine noun, less frequent
- déshydrogénase aldéhydique 4, record 1, French, d%C3%A9shydrog%C3%A9nase%20ald%C3%A9hydique
feminine noun, rare
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Les aldéhydes déshydrogénases sont des flavoprotéines hépatiques qui captent les aldéhydes et les oxydent en acides. Il existe plusieurs isoenzymes catalysant ces réactions, dans le cytoplasme ou les mitochondries de nombreuses cellules : foie, rein, cerveau, globules rouges. Au cours de l'oxydation de l'acétaldéhyde, un coenzyme NAD+ est encore réduit, et l'acide acétique produit est lié au coenzyme A par une liaison riche en énergie. L'acétyl-CoA issu de ce métabolisme pénètre dans la mitochondrie devient un substrat du cycle de Krebs. 5, record 1, French, - ald%C3%A9hyde%20d%C3%A9shydrog%C3%A9nase
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Bioquímica
Record 1, Main entry term, Spanish
- deshidrogenasa aldehídica
1, record 1, Spanish, deshidrogenasa%20aldeh%C3%ADdica
correct, feminine noun
Record 1, Abbreviations, Spanish
- ALDH 2, record 1, Spanish, ALDH
correct, feminine noun
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 CONT
El fármaco más usado en Chile para el tratamiento del alcoholismo es el disulfiram, cuyo efecto se basa en inactivar covalentemente la deshidrogenasa aldehídica(ALDH), enzima que elimina el acetaldehído producido en el metabolismo del etanol. 2, record 1, Spanish, - deshidrogenasa%20aldeh%C3%ADdica
Record 2 - internal organization data 2011-02-18
Record 2, English
Record 2, Subject field(s)
- Chemical Elements and Compounds
- Medication
- Agricultural Chemicals
Universal entry(ies) Record 2
Record 2, Main entry term, English
- disulfiram
1, record 2, English, disulfiram
correct
Record 2, Abbreviations, English
Record 2, Synonyms, English
- tetraethylthiuram disulfide 2, record 2, English, tetraethylthiuram%20disulfide
correct
Record 2, Textual support, English
Record number: 2, Textual support number: 1 OBS
An antioxidant used therapeutically to create an aversion to alcohol. 3, record 2, English, - disulfiram
Record number: 2, Textual support number: 2 OBS
Acaricide and fungicide. 4, record 2, English, - disulfiram
Record number: 2, Textual support number: 3 OBS
Chemical formula: C[ubscript 10]H20N2S4 4, record 2, English, - disulfiram
Record 2, French
Record 2, Domaine(s)
- Éléments et composés chimiques
- Médicaments
- Agents chimiques (Agriculture)
Entrée(s) universelle(s) Record 2
Record 2, Main entry term, French
- disulfirame
1, record 2, French, disulfirame
correct, masculine noun
Record 2, Abbreviations, French
Record 2, Synonyms, French
Record 2, Textual support, French
Record number: 2, Textual support number: 1 CONT
Dérivé aliphatique dont l'absorption entraîne une réaction d'allergie à l'alcool qui dure plusieurs jours. Pour cette raison, le disulfirame s'administre comme ajout dans le traitement d'un état de dépendance physique vis-à-vis de l'alcool. 2, record 2, French, - disulfirame
Record number: 2, Textual support number: 1 OBS
Acaricide et fongicide. 3, record 2, French, - disulfirame
Record number: 2, Textual support number: 2 OBS
Formule chimique : C10H20N2S4 3, record 2, French, - disulfirame
Record 2, Spanish
Record 2, Campo(s) temático(s)
- Elementos y compuestos químicos
- Medicamentos
- Agentes químicos (Agricultura)
Entrada(s) universal(es) Record 2
Record 2, Main entry term, Spanish
- disulfiram
1, record 2, Spanish, disulfiram
correct, masculine noun
Record 2, Abbreviations, Spanish
Record 2, Synonyms, Spanish
Record 2, Textual support, Spanish
Record number: 2, Textual support number: 1 CONT
El disulfiram [es], una droga que origina una reacción física adversa cuando se ingiere alcohol, es un elemento accesorio benéfico en el tratamiento de la dependencia del alcohol en determinados pacientes. 1, record 2, Spanish, - disulfiram
Record number: 2, Textual support number: 2 CONT
Fórmula química: C10H20N2S4 2, record 2, Spanish, - disulfiram
Record 3 - internal organization data 2010-02-09
Record 3, English
Record 3, Subject field(s)
- Pharmacodynamics
Record 3, Main entry term, English
- disulfiram-like reaction
1, record 3, English, disulfiram%2Dlike%20reaction
correct
Record 3, Abbreviations, English
Record 3, Synonyms, English
- disulfiram-like effect 2, record 3, English, disulfiram%2Dlike%20effect
correct
- disulfiram like reaction 2, record 3, English, disulfiram%20like%20reaction
- antabuse reaction 2, record 3, English, antabuse%20reaction
correct
- antabuse effect 2, record 3, English, antabuse%20effect
correct
Record 3, Textual support, English
Record number: 3, Textual support number: 1 CONT
Several pharmaceutical agents produce ethanol intolerance, which is often depicted as disulfiram-like reaction. 3, record 3, English, - disulfiram%2Dlike%20reaction
Record 3, French
Record 3, Domaine(s)
- Pharmacodynamie
Record 3, Main entry term, French
- effet disulfiram
1, record 3, French, effet%20disulfiram
correct, masculine noun
Record 3, Abbreviations, French
Record 3, Synonyms, French
- effet antabuse 1, record 3, French, effet%20antabuse
correct, masculine noun
Record 3, Textual support, French
Record 3, Spanish
Record 3, Campo(s) temático(s)
- Farmacodinámica
Record 3, Main entry term, Spanish
- efecto disulfiram
1, record 3, Spanish, efecto%20disulfiram
correct, masculine noun
Record 3, Abbreviations, Spanish
Record 3, Synonyms, Spanish
- efecto antabus 2, record 3, Spanish, efecto%20antabus
correct, masculine noun
- efecto antabús 3, record 3, Spanish, efecto%20antab%C3%BAs
correct, masculine noun
Record 3, Textual support, Spanish
Record number: 3, Textual support number: 1 CONT
[...] el disulfiram inhibe la aldehído deshidrogenasa que es una enzima que cataliza la reacción de oxidación del acetaldehído, que es el primer producto de metabolización del alcohol, e impide su transformación en ácido acético. La acumulación de aldehído da lugar a un cuadro clínico muy típico y muy molesto para el paciente con : náuseas, vómitos, sudoración profusa, taquicardia, etc. Es el llamado efecto antabús. 3, record 3, Spanish, - efecto%20disulfiram
Copyright notice for the TERMIUM Plus® data bank
© Public Services and Procurement Canada, 2025
TERMIUM Plus®, the Government of Canada's terminology and linguistic data bank
A product of the Translation Bureau
Features
Language Portal of Canada
Access a collection of Canadian resources on all aspects of English and French, including quizzes.
Writing tools
The Language Portal’s writing tools have a new look! Easy to consult, they give you access to a wealth of information that will help you write better in English and French.
Glossaries and vocabularies
Access Translation Bureau glossaries and vocabularies.
- Date Modified: